Eszopiclone
- Generic Name
- Eszopiclone
- Brand Names
- Lunesta
- Drug Type
- Small Molecule
- Chemical Formula
- C17H17ClN6O3
- CAS Number
- 138729-47-2
- Unique Ingredient Identifier
- UZX80K71OE
- Background
Eszopiclone, marketed by Sepracor under the brand-name Lunesta, is a nonbenzodiazepine hypnotic drug used to treat insomnia. It is the active stereoisomer of zopiclone, belonging to the class of drugs known as cyclopyrrolones. Cyclopyrrolone drugs demonstrate high efficacy and low toxicity, offering a safer alternative to other drugs used for insomnia.
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- Indication
Eszopiclone is indicated for the treatment of insomnia.
- Associated Conditions
- Insomnia
- Associated Therapies
- -
Do Endotypes Predict Response and Sequelae in OSA Patients
- First Posted Date
- 2021-05-06
- Last Posted Date
- 2024-10-02
- Lead Sponsor
- University of California, San Diego
- Target Recruit Count
- 200
- Registration Number
- NCT04875364
- Locations
- 🇺🇸
Altman Clinical and Translational Research Institute Building, La Jolla, California, United States
Combination Drug-Therapy for Patients With Untreated Obstructive Sleep Apnea
- Conditions
- Interventions
- First Posted Date
- 2020-11-20
- Last Posted Date
- 2024-05-29
- Lead Sponsor
- University of California, San Diego
- Target Recruit Count
- 20
- Registration Number
- NCT04639193
- Locations
- 🇺🇸
Altman Clinical and Translational Research Institute Building, La Jolla, California, United States
🇺🇸UCSD Health - Pulmonary and Sleep Clinic, La Jolla, California, United States
Effectiveness of Combining Behavioral and Pharmacologic Therapy for Complex Insomnia in Veterans With PTSD
- Conditions
- Interventions
- First Posted Date
- 2019-05-06
- Last Posted Date
- 2024-03-22
- Lead Sponsor
- VA Office of Research and Development
- Target Recruit Count
- 52
- Registration Number
- NCT03937713
- Locations
- 🇺🇸
VA Western New York Healthcare System, Buffalo, NY, Buffalo, New York, United States
National Adaptive Trial for PTSD Related Insomnia
- First Posted Date
- 2018-09-12
- Last Posted Date
- 2024-12-19
- Lead Sponsor
- VA Office of Research and Development
- Target Recruit Count
- 774
- Registration Number
- NCT03668041
- Locations
- 🇺🇸
Birmingham VA Medical Center, Birmingham, AL, Birmingham, Alabama, United States
🇺🇸Tuscaloosa VA Medical Center, Tuscaloosa, AL, Tuscaloosa, Alabama, United States
🇺🇸Phoenix VA Health Care System, Phoenix, AZ, Phoenix, Arizona, United States
Safety and Efficacy of Chronic Hypnotic Use 2
- Conditions
- Interventions
- First Posted Date
- 2015-05-28
- Last Posted Date
- 2024-03-29
- Lead Sponsor
- Henry Ford Health System
- Target Recruit Count
- 41
- Registration Number
- NCT02456532
- Locations
- 🇺🇸
HFHS Sleep Disorders Ctr, Detroit, Michigan, United States
Investigation of the Safety and Efficacy of Long Term Administration of Eszopiclone in Insomnia Patients
- First Posted Date
- 2015-05-27
- Last Posted Date
- 2018-09-07
- Lead Sponsor
- Eisai Co., Ltd.
- Target Recruit Count
- 438
- Registration Number
- NCT02455271
Investigation of the Safety and Efficacy of Eszopiclone in Insomnia Patients
- First Posted Date
- 2015-05-25
- Last Posted Date
- 2018-09-07
- Lead Sponsor
- Eisai Co., Ltd.
- Target Recruit Count
- 4876
- Registration Number
- NCT02452684
Auricular Acupuncture for Primary Insomnia
- Conditions
- Interventions
- First Posted Date
- 2014-03-14
- Last Posted Date
- 2020-02-17
- Target Recruit Count
- 288
- Registration Number
- NCT02087488
- Locations
- 🇨🇳
Chengdu university of Traditonal Chinese Medcine, Chengdu, Sichuan, China
Sleep Effectiveness and Insulin and Glucose Homeostasis
- Conditions
- Interventions
- First Posted Date
- 2013-06-27
- Last Posted Date
- 2019-12-19
- Lead Sponsor
- Beth Israel Deaconess Medical Center
- Target Recruit Count
- 20
- Registration Number
- NCT01887691
- Locations
- 🇺🇸
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
Effects of Eszopiclone on Sleep and Memory in Schizophrenia
- First Posted Date
- 2012-07-17
- Last Posted Date
- 2017-06-14
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 59
- Registration Number
- NCT01641900
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.