MedPath

Trehalose

Generic Name
Trehalose
Drug Type
Small Molecule
Chemical Formula
C12H22O11
CAS Number
99-20-7
Unique Ingredient Identifier
B8WCK70T7I
Background

Cabaletta has been used in trials studying the treatment of Oculopharyngeal Muscular Dystrophy.

Inflammation Reduction by TREhalose AdminisTration

Phase 2
Conditions
Acute Coronary Syndrome
Interventions
Drug: Normal saline
First Posted Date
2018-10-09
Last Posted Date
2020-09-21
Lead Sponsor
Mashhad University of Medical Sciences
Target Recruit Count
15
Registration Number
NCT03700424
Locations
🇮🇷

Ghaem Educational, Research and Treatment Center, Mashhad, Razavi Khorasan, Iran, Islamic Republic of

Trehalose as add-on Therapy in Bipolar Depression

Phase 3
Completed
Conditions
Bipolar Depression
Bipolar Disorder
Interventions
First Posted Date
2016-06-15
Last Posted Date
2023-02-08
Lead Sponsor
Consorcio Centro de Investigación Biomédica en Red (CIBER)
Target Recruit Count
60
Registration Number
NCT02800161
Locations
🇪🇸

Hospital Clinic of Barcelona, Barcelona, Spain

A Study to Establish Safety and Maximum Tolerated Dose of IV Trehalose in Healthy Subjects

Phase 1
Completed
Conditions
Healthy Volunteer Subjects
Interventions
First Posted Date
2016-04-01
Last Posted Date
2016-11-22
Lead Sponsor
Bioblast Pharma Ltd.
Target Recruit Count
24
Registration Number
NCT02725957
Locations
🇺🇸

PAREXEL Baltimore Early Phase Clinical Unit; Harbor Hospital, Baltimore, Maryland, United States

Study To Assess Safety, Tolerability and Efficacy of Intravenous Cabaletta in Patients With Machado-Joseph Disease

Phase 2
Completed
Conditions
Machado-Joseph Disease / Spinocerebellar Ataxia 3
Interventions
First Posted Date
2014-05-28
Last Posted Date
2016-11-22
Lead Sponsor
Bioblast Pharma Ltd.
Target Recruit Count
15
Registration Number
NCT02147886
Locations
🇮🇱

Meir Medical Center, Kfar Saba, Israel

Safety Tolerability and Efficacy Study of Cabaletta to Treat Oculopharyngeal Muscular Dystrophy (OPMD) Patients

Phase 2
Completed
Conditions
Oculopharyngeal Muscular Dystrophy
Interventions
First Posted Date
2013-12-19
Last Posted Date
2017-10-17
Lead Sponsor
Bioblast Pharma Ltd.
Target Recruit Count
25
Registration Number
NCT02015481
Locations
🇨🇦

Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada

🇺🇸

UCLA, Los Angeles, California, United States

🇮🇱

Hadassah medical center, Jerusalem, Israel

and more 1 locations

Oral Trehalose Therapy to Reverse Arterial Aging in Middle-Aged and Older Adults

Not Applicable
Completed
Conditions
Vascular Aging
Interventions
First Posted Date
2012-04-11
Last Posted Date
2015-12-11
Lead Sponsor
University of Colorado, Boulder
Target Recruit Count
110
Registration Number
NCT01575288
Locations
🇺🇸

University of Colorado, Boulder Clinical Translational Research Center, Boulder, Colorado, United States

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