MedPath

Tyrosine

Generic Name
Tyrosine
Brand Names
Premasol, Clinimix E 2.75/5, Aminosyn-PF 7%, Primene, Clinimix 2.75/5, Trophamine 10 %, Plenamine, Olimel, Prosol, Clinisol 15, Periolimel, Travasol 10
Drug Type
Small Molecule
Chemical Formula
C9H11NO3
CAS Number
60-18-4
Unique Ingredient Identifier
42HK56048U
Background

Tyrosine is a non-essential amino acid. In animals it is synthesized from phenylalanine. It is also the precursor of epinephrine, thyroid hormones, and melanin.

Indication

Tyrosine is claimed to act as an effective antidepressant, however results are mixed. Tyrosine has also been claimed to reduce stress and combat narcolepsy and chronic fatigue, however these claims have been refuted by some studies.

Associated Conditions
Acute Renal Dysfunction, Renal Failure, Chronic Renal Failure
Associated Therapies
Amino acid supplementation

A Prospective Clinical Trial in Chronic Hepatitis B Patients NAs (Nucleotides or Nucleosides) Experienced (Anchor Study)

Phase 3
Conditions
Hepatitis B, Chronic
Interventions
Drug: Granulocyte-macrophage colony stimulating factor
First Posted Date
2014-12-30
Last Posted Date
2016-08-15
Lead Sponsor
Tongji Hospital
Target Recruit Count
300
Registration Number
NCT02327416
Locations
🇨🇳

Beijing Youan Hospital, Beijing, Beijing, China

🇨🇳

Tongji Hospital, Wuhan, Hubei, China

🇨🇳

Xiangya Hospital, Central South University, Changsha, Hunan, China

and more 1 locations

A Open-label Prospective Cohort Trial of Curcumin Plus Tyrosine Kinase Inhibitors (TKI) for EGFR -Mutant Advanced NSCLC

Phase 1
Conditions
Lung Cancer
Interventions
First Posted Date
2014-12-22
Last Posted Date
2015-09-02
Lead Sponsor
Lady Davis Institute
Target Recruit Count
20
Registration Number
NCT02321293
Locations
🇨🇦

Peter Brojge Lung Cancer Center, Jewish General Hospital, Montreal, Quebec, Canada

Treatment of TNNT1-Myopathy With L-Tyrosine.

Phase 2
Conditions
Nemaline Myopathy
Interventions
Drug: Placebo
First Posted Date
2014-01-14
Last Posted Date
2014-01-14
Lead Sponsor
Hadassah Medical Organization
Target Recruit Count
10
Registration Number
NCT02035501
Locations
🇮🇱

Hadassah Medical Organization, Jerusalem, Israel, Jerusalem, Israel

Y Zevalin and BEAM in Autologous Stem Cell Transplantation (ASCT) for Lymphoma

Phase 1
Completed
Conditions
Lymphoma
Interventions
First Posted Date
2012-02-24
Last Posted Date
2014-09-11
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
40
Registration Number
NCT01538472
Locations
🇺🇸

UT MD Anderson Cancer Center, Houston, Texas, United States

Azacitidine (AZA) in Minimal Residual Disease (MRD) Chronic Myeloid Leukemia (CML)

First Posted Date
2011-10-27
Last Posted Date
2020-03-05
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
3
Registration Number
NCT01460498
Locations
🇺🇸

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

L-Tyrosine Supplementation in Patients With Fibromyalgia

Not Applicable
Terminated
Conditions
Fibromyalgia
Interventions
Drug: Placebo
First Posted Date
2010-10-13
Last Posted Date
2017-04-11
Lead Sponsor
Icahn School of Medicine at Mount Sinai
Target Recruit Count
15
Registration Number
NCT01219049
Locations
🇺🇸

Mount Sinai School of Medicine, New York, New York, United States

Liver Function Test (LFT) Elevations in Cancer Patients and Users of Tyrosine Kinase Inhibitor (TKI) Drugs

Completed
Conditions
Cancer
Interventions
First Posted Date
2010-04-02
Last Posted Date
2017-05-30
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
3800
Registration Number
NCT01098500
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