Calcipotriol
- Generic Name
- Calcipotriol
- Brand Names
- Calcitrene, Dovobet, Dovonex, Enstilar, Sorilux, Taclonex, Wynzora
- Drug Type
- Small Molecule
- Chemical Formula
- C27H40O3
- CAS Number
- 112965-21-6
- Unique Ingredient Identifier
- 143NQ3779B
- Background
Calcipotriol (INN) or calcipotriene (USAN) is a sythetic derivative of calcitriol or Vitamin D.
- Indication
For the treatment of moderate plaque psoriasis in adults.
- Associated Conditions
- Plaque psoriasis of the scalp, Psoriasis Vulgaris (Plaque Psoriasis)
Study to Compare U0267 Against Vehicle in Subjects With Plaque-type Psoriasis One of Two Phase 3 Studies
- First Posted Date
- 2008-06-03
- Last Posted Date
- 2017-01-02
- Lead Sponsor
- Stiefel, a GSK Company
- Target Recruit Count
- 336
- Registration Number
- NCT00688519
- Locations
- 🇺🇸
Minnesota Clinical Study Center, Fridley, Minnesota, United States
🇺🇸Mount Sinai School of Medicine, Department of Dermatology, New York, New York, United States
🇺🇸Dermatology Consulting Services, High Point, North Carolina, United States
Efficacy and Safety of Calcipotriol Plus Betamethasone Dipropionate Gel Compared With Tacalcitol Ointment and the Gel Vehicle Alone in Patients With Psoriasis Vulgaris
- Conditions
- Psoriasis Vulgaris
- Interventions
- Drug: LEO 80185 vehicle
- First Posted Date
- 2008-05-01
- Last Posted Date
- 2025-03-10
- Lead Sponsor
- LEO Pharma
- Target Recruit Count
- 458
- Registration Number
- NCT00670241
- Locations
- 🇨🇦
Eastern Canada Cutaneous Research Associates Ltd., Halifax, Nova Scotia, Canada
Efficacy and Safety of Calcipotriol Plus Hydrocortisone Ointment Compared With Tacalcitol Ointment in Patients With Psoriasis on the Face and Skin Folds
- Conditions
- Psoriasis Vulgaris
- Interventions
- First Posted Date
- 2008-03-21
- Last Posted Date
- 2025-03-07
- Lead Sponsor
- LEO Pharma
- Target Recruit Count
- 782
- Registration Number
- NCT00640822
- Locations
- 🇨🇦
Probity Medical Research, Waterloo, Ontario, Canada
🇫🇷Hôpital de l'Archet, Nice, France
🇬🇧Ninewells Hospital & Medical School, Dundee, United Kingdom
Study of Dose-Effect of COL-121 Ointment in Patients With Plaque-Type Psoriasis
- Conditions
- Plaque-type Psoriasis
- Interventions
- First Posted Date
- 2008-02-28
- Last Posted Date
- 2011-04-27
- Lead Sponsor
- Deltanoid Pharmaceuticals
- Target Recruit Count
- 321
- Registration Number
- NCT00625326
- Locations
- 🇺🇸
East Bay Dermatology Medical Group, Fremont, California, United States
🇺🇸Michigan Center for Skin Care Research, Clinton Township, Michigan, United States
🇺🇸The Education & Research Foundation, Inc., Lynchburg, Virginia, United States
Efficacy and Tolerability Study of Topical Ciclosporin in a Psoriasis Plaque Test
- Conditions
- Psoriasis
- Interventions
- First Posted Date
- 2007-12-21
- Last Posted Date
- 2008-11-05
- Lead Sponsor
- ISDIN
- Target Recruit Count
- 25
- Registration Number
- NCT00578370
- Locations
- 🇩🇪
Bioskin, Hamburg, Germany
The Role of Calcipotriol as Radioprotector of Skin
- Conditions
- Radiodermatitis
- First Posted Date
- 2007-03-08
- Last Posted Date
- 2007-03-08
- Lead Sponsor
- Rabin Medical Center
- Target Recruit Count
- 50
- Registration Number
- NCT00445250
- Locations
- 🇮🇱
Rabin Medical Center, Petach Tiqva, Israel
A Study of Sequential Treatment With Daivobet (Betamethasone Dipropionate Plus Calcipotriol) and Daivonex (Calcipotriol) in Patients With Psoriasis.
- First Posted Date
- 2007-02-21
- Last Posted Date
- 2015-12-02
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 200
- Registration Number
- NCT00437619
Efficacy, Safety, Preference and Response Duration of Clobex® Spray and Taclonex® Ointment in Psoriasis
- Conditions
- Plaque Psoriasis
- Interventions
- First Posted Date
- 2007-02-19
- Last Posted Date
- 2022-07-29
- Lead Sponsor
- Galderma R&D
- Target Recruit Count
- 122
- Registration Number
- NCT00437255
- Locations
- 🇺🇸
Minnesota Clinical Study Center, Fridley, Minnesota, United States
🇺🇸J & S Studies, Inc., Bryan, Texas, United States
🇺🇸Baylor Research Institute, Dallas, Texas, United States
LEO19123 Cream in the Treatment of Hand Eczema
- Conditions
- Hand Eczema
- First Posted Date
- 2006-11-28
- Last Posted Date
- 2025-02-24
- Lead Sponsor
- LEO Pharma
- Target Recruit Count
- 75
- Registration Number
- NCT00404196
- Locations
- 🇬🇧
Queen's Medical Centre, Nottingham, United Kingdom
LEO19123 Cream in the Treatment of Atopic Dermatitis
- Conditions
- Atopic Dermatitis
- First Posted Date
- 2006-10-25
- Last Posted Date
- 2025-02-24
- Lead Sponsor
- LEO Pharma
- Target Recruit Count
- 75
- Registration Number
- NCT00392067
- Locations
- 🇬🇧
Manchester Royal Infirmary, Manchester, United Kingdom
🇨🇦Clinique Dermatologique Maizerets, Quebec City, Quebec, Canada
🇫🇮Helsinki University Central Hospital, Helsinki, Finland
Drug Development Updates
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