Calcipotriol
- Generic Name
- Calcipotriol
- Brand Names
- Calcitrene, Dovobet, Dovonex, Enstilar, Sorilux, Taclonex, Wynzora
- Drug Type
- Small Molecule
- Chemical Formula
- C27H40O3
- CAS Number
- 112965-21-6
- Unique Ingredient Identifier
- 143NQ3779B
- Background
Calcipotriol (INN) or calcipotriene (USAN) is a sythetic derivative of calcitriol or Vitamin D.
- Indication
For the treatment of moderate plaque psoriasis in adults.
- Associated Conditions
- Plaque psoriasis of the scalp, Psoriasis Vulgaris (Plaque Psoriasis)
LEO 80185 in the Treatment of Psoriasis Vulgaris on the Non-scalp Regions of the Body (Trunk and/or Limbs)
- Conditions
- Psoriasis Vulgaris
- Interventions
- Drug: Topical suspension vehicleDrug: Betamethasone-17,21-dipropionate
- First Posted Date
- 2010-08-26
- Last Posted Date
- 2025-03-10
- Lead Sponsor
- LEO Pharma
- Target Recruit Count
- 1152
- Registration Number
- NCT01188928
- Locations
- 🇺🇸
Horizon Research Group, Inc, Mobile, Alabama, United States
🇺🇸Burke Pharmaceutical Research, Hot Springs, Arkansas, United States
🇺🇸Advanced Clinical Research Institute, Anaheim, California, United States
The Purpose of This Study is to Demonstrate the Safety and Effectiveness of Calcipotriene Foam in Subjects With Scalp and Body Psoriasis
- First Posted Date
- 2010-06-08
- Last Posted Date
- 2017-01-18
- Lead Sponsor
- Stiefel, a GSK Company
- Target Recruit Count
- 363
- Registration Number
- NCT01139580
- Locations
- 🇺🇸
Miami Dermatology Research Institute LLC, North Miami Beach, Florida, United States
🇺🇸MedaPhase, Inc., Newnan, Georgia, United States
🇺🇸Gwinnett Clinical Research Center, Inc., Snellville, Georgia, United States
Taclonex Ointment With Hydrogel Patch Occlusion for the Treatment of Psoriasis
- Conditions
- Plaque PsoriasisPsoriasis Vulgaris
- Interventions
- First Posted Date
- 2009-06-19
- Last Posted Date
- 2019-04-18
- Lead Sponsor
- University of California, San Francisco
- Target Recruit Count
- 35
- Registration Number
- NCT00924950
- Locations
- 🇺🇸
UCSF Psoriasis Skin and Treatment Center, San Francisco, California, United States
A Study of Ruxolitinib Phosphate Cream When Applied to Patients With Plaque Psoriasis
- Conditions
- Psoriasis
- Interventions
- First Posted Date
- 2009-01-12
- Last Posted Date
- 2022-02-08
- Lead Sponsor
- Incyte Corporation
- Target Recruit Count
- 29
- Registration Number
- NCT00820950
Safety and Efficacy of TACLONEX Ointment in Adolescent Patients (Aged 12 to 17 Years) With Psoriasis Vulgaris
- Conditions
- Psoriasis Vulgaris
- Interventions
- First Posted Date
- 2009-01-06
- Last Posted Date
- 2025-03-12
- Lead Sponsor
- LEO Pharma
- Target Recruit Count
- 33
- Registration Number
- NCT00817219
- Locations
- 🇺🇸
Center for Dermatology Clinical Research, Fremont, California, United States
🇺🇸University of California at San Diego/Rady Children's Hospital, San Diego, California, United States
🇺🇸Northwestern University's Feinberg School of Medicine, Chicago, Illinois, United States
A Single-Center Exploratory Study to Assess the Activity of CRx-197-002 in Plaque Psoriasis
- Conditions
- Plaque Psoriasis
- Interventions
- First Posted Date
- 2008-11-24
- Last Posted Date
- 2009-01-15
- Lead Sponsor
- Zalicus
- Target Recruit Count
- 20
- Registration Number
- NCT00796211
- Locations
- 🇩🇪
ProInnovera, Muenster, Germany
Efficacy and Safety of LEO 19123 Cream in the Treatment of Psoriasis Vulgaris
- Conditions
- Psoriasis Vulgaris
- Interventions
- First Posted Date
- 2008-10-02
- Last Posted Date
- 2025-03-07
- Lead Sponsor
- LEO Pharma
- Target Recruit Count
- 51
- Registration Number
- NCT00764751
- Locations
- 🇨🇦
UltraNova Skincare, Barrie, Ontario, Canada
LCD Solution Versus Calcipotriol Cream in the Treatment of Moderate Plaque Psoriasis
- First Posted Date
- 2008-06-27
- Last Posted Date
- 2008-11-19
- Lead Sponsor
- NeoStrata Company, Inc.
- Target Recruit Count
- 60
- Registration Number
- NCT00705900
- Locations
- 🇺🇸
Mass General Hospital: Clinical Unit for Research Trials in Skin, Boston, Massachusetts, United States
Effect of Calcipotriol Plus Hydrocortisone Ointment on the Adrenal Hormone Balance and Calcium Metabolism in Patients With Psoriasis Vulgaris on the Face and Skin Folds
- Conditions
- Psoriasis Vulgaris
- Interventions
- First Posted Date
- 2008-06-24
- Last Posted Date
- 2025-03-25
- Lead Sponsor
- LEO Pharma
- Target Recruit Count
- 33
- Registration Number
- NCT00704262
- Locations
- 🇺🇸
Burke Pharmaceuticals, Hot Springs, Arkansas, United States
🇺🇸Dermatology Research of Arkansas, Little Rock, Arkansas, United States
🇺🇸Ameriderm Research, Ormond Beach, Florida, United States
Efficacy and Safety of Calcipotriol Plus Hydrocortisone Ointment in Psoriasis Vulgaris on the Face and Skin Folds
- Conditions
- Psoriasis Vulgaris
- Interventions
- Drug: LEO 80190 Vehicle
- First Posted Date
- 2008-06-05
- Last Posted Date
- 2025-03-10
- Lead Sponsor
- LEO Pharma
- Target Recruit Count
- 1245
- Registration Number
- NCT00691002
- Locations
- 🇵🇱
Latvia - managed by CRO, Warszawa, Poland
🇷🇸Serbia - managed by CRO, New Belgrade, Serbia
🇵🇱Hungary - managed by CRO, Warszawa, Poland
Drug Development Updates
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