Modafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy. Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by modafinil. The prexin neuron activation is associated with psychoactiva...
To improve wakefulness in patients with excessive daytime sleepiness (EDS) associated with narcolepsy.
University of Chicago Medical Center, Chicago, Illinois, United States
Parexel Early Phase Unit at Glendale, Glendale, California, United States
Michael Debakey VA Medical Center, Houston, Texas, United States
Penn State Hershey Medical Center, Hershey, Pennsylvania, United States
Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea, Republic of
Wake Forest School of Medicine, Winston-Salem, North Carolina, United States
Department of Psychiatry, Cambridge School of Clinical Medicine, Cambridge, Cambridgeshire, United Kingdom
Brigham & Women's Hospital, Boston, Massachusetts, United States
Brigham and Women's Hospital, Boston, Massachusetts, United States
Vanderbilt University, Nashville, Tennessee, United States
Icahn School of Medicine at Mount Sinai, New York, New York, United States
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