Hyaluronic acid
- Generic Name
- Hyaluronic acid
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C28H44N2O23
- CAS Number
- 9004-61-9
- Unique Ingredient Identifier
- S270N0TRQY
- Background
Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and neural tissues; it was first isolated in 1934. Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “hyaluronic acid”. HA is involved in many important physiological processes, including but not limited to woun...
- Indication
The intra-articular preparations of hyaluronic acid are indicated for knee pain associated with osteoarthritis. Hyaluronic acid is used in cosmetic applications to prevent and reduce the appearance of wrinkles on the face, and as a dermal filler to correct facial imperfections or other imperfections on other parts of the body. It is frequently an ingredient ...
- Associated Conditions
- Actinic Keratosis (AK), Burns, Chronic Skin Ulcers, Conjunctivitis, Dehydration, Dermabrasion, Dermatosis, Dry Eyes, Facial Defect, Interstitial Cystitis, Keratoconjunctivitis, Ocular Irritation, Osteoarthritis (OA), Pain of the knee, Seasonal Allergic Conjunctivitis, Skin Burn, Skin Irritation, Skin fissures, Tissue Adhesions, Varicose Ulcers, Wound, Eye discomfort, Facial fine wrinkling, Sensation of burning in the eyes, Superficial Wounds
- Associated Therapies
- Dermal Filler, Promotion of wound healing, Synovial Fluid Lubrication
Functional Improvement and UTC of the Achilles Tendon After Sodium Hyaluronate Injection for Plantaris Syndrome
- Conditions
- Interventions
- First Posted Date
- 2017-03-10
- Last Posted Date
- 2017-03-10
- Lead Sponsor
- Fortius Clinic
- Target Recruit Count
- 33
- Registration Number
- NCT03077009
- Locations
- 🇬🇧
Fortius Clinic, London, United Kingdom
Intra-Articular, Single-shot Injection of Hyaluronic Acid and Corticosteroids in Knee Osteoarthritis
- Conditions
- Interventions
- First Posted Date
- 2017-02-08
- Last Posted Date
- 2017-02-10
- Lead Sponsor
- Zhongda Hospital
- Target Recruit Count
- 120
- Registration Number
- NCT03047096
- Locations
- 🇨🇳
Zhongda Hospital, Nanjing, Jiangsu, China
Intra-articular Injection of MSCs in Treatment of Knee OA
- Conditions
- Interventions
- First Posted Date
- 2017-01-23
- Last Posted Date
- 2018-01-30
- Lead Sponsor
- Affiliated Hospital of Jiangsu University
- Target Recruit Count
- 1
- Registration Number
- NCT03028428
Platelet-rich Plasma vs. Hyaluronic Acid for Glenohumeral Osteoarthritis
- Conditions
- Interventions
- First Posted Date
- 2016-12-06
- Last Posted Date
- 2022-08-08
- Lead Sponsor
- Hospital for Special Surgery, New York
- Target Recruit Count
- 70
- Registration Number
- NCT02984228
- Locations
- 🇺🇸
Hospital for Special Surgery, New York, New York, United States
Autologous Adipose-Derived Stromal Vascular Fraction Cells for Osteoarthritis Treatment
- First Posted Date
- 2016-11-18
- Last Posted Date
- 2019-09-13
- Lead Sponsor
- Russian Academy of Medical Sciences
- Target Recruit Count
- 27
- Registration Number
- NCT02967874
- Locations
- 🇷🇺
Institute of Fundamental and Clinical Immunology, Novosibirsk, Russian Federation
Treatment of Knee Arthrosis With Platelet-derived Growth Factors vs. Hyaluronic Acid.
- Conditions
- Interventions
- First Posted Date
- 2016-11-08
- Last Posted Date
- 2016-11-09
- Lead Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
- Target Recruit Count
- 58
- Registration Number
- NCT02958761
Clinical Trial to Compare ReJoinTM to Sodium Hyaluronate Injection for Knee Osteoarthritis Cartilage Defects
- Conditions
- Interventions
- First Posted Date
- 2016-08-04
- Last Posted Date
- 2018-12-17
- Lead Sponsor
- Shanghai AbelZeta Ltd.
- Target Recruit Count
- 28
- Registration Number
- NCT02855073
- Locations
- 🇨🇳
Shanghai ninth people's hospital, Shanghai, Shanghai, China
Role of Hyaluronic Acid in the Prevention of Post-operative Adhesions: a RCT
- First Posted Date
- 2016-06-03
- Last Posted Date
- 2016-06-03
- Lead Sponsor
- Services Institute of Medical Sciences, Pakistan
- Target Recruit Count
- 150
- Registration Number
- NCT02790177
Evaluation of Efficacy of Aloevera in the Treatment of Oral Submucous Fibrosis- A Clinical Study
- Conditions
- Interventions
- First Posted Date
- 2016-03-21
- Last Posted Date
- 2016-03-21
- Target Recruit Count
- 74
- Registration Number
- NCT02714543
Use of Hyaluronic Acid as a Therapeutic Strategy for Bone Repair in Human
- First Posted Date
- 2016-03-16
- Last Posted Date
- 2016-03-16
- Lead Sponsor
- Federal University of Minas Gerais
- Target Recruit Count
- 16
- Registration Number
- NCT02709525
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