Hyaluronic acid
- Generic Name
- Hyaluronic acid
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C28H44N2O23
- CAS Number
- 9004-61-9
- Unique Ingredient Identifier
- S270N0TRQY
- Background
Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and neural tissues; it was first isolated in 1934. Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “hyaluronic acid”. HA is involved in many important physiological processes, including but not limited to woun...
- Indication
The intra-articular preparations of hyaluronic acid are indicated for knee pain associated with osteoarthritis. Hyaluronic acid is used in cosmetic applications to prevent and reduce the appearance of wrinkles on the face, and as a dermal filler to correct facial imperfections or other imperfections on other parts of the body. It is frequently an ingredient ...
- Associated Conditions
- Actinic Keratosis (AK), Burns, Chronic Skin Ulcers, Conjunctivitis, Dehydration, Dermabrasion, Dermatosis, Dry Eyes, Facial Defect, Interstitial Cystitis, Keratoconjunctivitis, Ocular Irritation, Osteoarthritis (OA), Pain of the knee, Seasonal Allergic Conjunctivitis, Skin Burn, Skin Irritation, Skin fissures, Tissue Adhesions, Varicose Ulcers, Wound, Eye discomfort, Facial fine wrinkling, Sensation of burning in the eyes, Superficial Wounds
- Associated Therapies
- Dermal Filler, Promotion of wound healing, Synovial Fluid Lubrication
Effect of Ultrasound-guided Hyaluronic or Corticosteroid Injections in Patients With Chronic Subacromial Bursitis
- Conditions
- Interventions
- First Posted Date
- 2016-03-08
- Last Posted Date
- 2020-12-23
- Lead Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
- Target Recruit Count
- 207
- Registration Number
- NCT02702206
- Locations
- 🇨🇳
Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan
Safety Study of Filler Agent Composed of Umbilical Cord Mesenchymal Stem Cells and Hyaluronic Acid
- First Posted Date
- 2016-03-04
- Last Posted Date
- 2016-03-04
- Target Recruit Count
- 30
- Registration Number
- NCT02698813
A Study to Assess Safety and Efficacy of Umbilical Cord-derived Mesenchymal Stromal Cells in Knee Osteoarthritis
- Conditions
- Interventions
- First Posted Date
- 2015-10-20
- Last Posted Date
- 2018-12-26
- Lead Sponsor
- Francisco Espinoza, MD
- Target Recruit Count
- 30
- Registration Number
- NCT02580695
- Locations
- 🇨🇱
Clinica Universidad de los Andes, Santiago, Chile
Minimally Invasive Volume Augmentation of Papillae Around Implant Restorations With Hyaluronic Acid Injection
- First Posted Date
- 2015-09-01
- Last Posted Date
- 2016-09-20
- Lead Sponsor
- Malmö University
- Target Recruit Count
- 22
- Registration Number
- NCT02536807
- Locations
- 🇸🇪
School of Dentistry, Malmö University, Malmö, Sweden
Hemiplegic Shoulder Pain and Rotator Cuff Injuries
- Conditions
- Interventions
- First Posted Date
- 2015-06-09
- Last Posted Date
- 2018-02-26
- Lead Sponsor
- Chang Gung Memorial Hospital
- Target Recruit Count
- 42
- Registration Number
- NCT02465853
- Locations
- 🇨🇳
ChangGungMH, Kaohsiung, Taiwan
EuroPainClinics® Study II (Prospective Trial)
- Conditions
- Interventions
- First Posted Date
- 2015-06-02
- Last Posted Date
- 2022-01-03
- Lead Sponsor
- Europainclinics z.ú.
- Target Recruit Count
- 300
- Registration Number
- NCT02459392
- Locations
- 🇨🇿
Czech republic, Praha, Czechia
Intraarticular Injections of Platelet-rich Plasma in Pain's Treatment of the Osteoarthritic Knee
- Conditions
- Interventions
- First Posted Date
- 2015-05-19
- Last Posted Date
- 2015-05-19
- Target Recruit Count
- 52
- Registration Number
- NCT02448407
Role of Hyaluronic Acid in Bone Healing After Dental Extraction
- First Posted Date
- 2015-01-05
- Last Posted Date
- 2015-09-29
- Lead Sponsor
- Damascus University
- Target Recruit Count
- 20
- Registration Number
- NCT02330822
- Locations
- 🇸🇾
Department of Oral and Maxillofacial Surgery, University of Damascus Dental School, Damascus, Damscus, Syrian Arab Republic
Hylenex-Assisted Resuscitation in Kenya (HARK) Trial for the Management of Dehydration
- First Posted Date
- 2014-10-16
- Last Posted Date
- 2019-03-07
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 51
- Registration Number
- NCT02265575
- Locations
- 🇰🇪
Sagam Community Hospital, Luanda, Kenya
Comparison of Autologous Platelet-rich Plasma With Hyaluronic Acid for the Treatment of Osteoarthritis of the Knee Joint
- First Posted Date
- 2014-08-07
- Last Posted Date
- 2015-12-10
- Lead Sponsor
- Samsung Medical Center
- Target Recruit Count
- 110
- Registration Number
- NCT02211521
- Locations
- 🇰🇷
Samsung Medical Center, Seoul, Korea, Republic of
Drug Development Updates
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