Hyaluronic acid
- Generic Name
- Hyaluronic acid
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C28H44N2O23
- CAS Number
- 9004-61-9
- Unique Ingredient Identifier
- S270N0TRQY
- Background
Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and neural tissues; it was first isolated in 1934. Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “hyaluronic acid”. HA is involved in many important physiological processes, including but not limited to woun...
- Indication
The intra-articular preparations of hyaluronic acid are indicated for knee pain associated with osteoarthritis. Hyaluronic acid is used in cosmetic applications to prevent and reduce the appearance of wrinkles on the face, and as a dermal filler to correct facial imperfections or other imperfections on other parts of the body. It is frequently an ingredient ...
- Associated Conditions
- Actinic Keratosis (AK), Burns, Chronic Skin Ulcers, Conjunctivitis, Dehydration, Dermabrasion, Dermatosis, Dry Eyes, Facial Defect, Interstitial Cystitis, Keratoconjunctivitis, Ocular Irritation, Osteoarthritis (OA), Pain of the knee, Seasonal Allergic Conjunctivitis, Skin Burn, Skin Irritation, Skin fissures, Tissue Adhesions, Varicose Ulcers, Wound, Eye discomfort, Facial fine wrinkling, Sensation of burning in the eyes, Superficial Wounds
- Associated Therapies
- Dermal Filler, Promotion of wound healing, Synovial Fluid Lubrication
A Double Blind Study Comparing Hyaluronic Acid, Corticosteroid and Placebo During Arthrocentesis for Temporomandibular Joint (TMJ) Dysfunction
- Conditions
- Interventions
- First Posted Date
- 2012-02-02
- Last Posted Date
- 2017-05-05
- Lead Sponsor
- Emory University
- Target Recruit Count
- 102
- Registration Number
- NCT01524913
- Locations
- 🇺🇸
University of Cinncinati, Cinncinati, Ohio, United States
🇺🇸University California Los Angeles, Los Angeles, California, United States
🇺🇸Emory University, Atlanta, Georgia, United States
Efficacy and Safety Study in Patients Suffering From Knee Osteoarthritis
- Conditions
- Interventions
- First Posted Date
- 2011-11-10
- Last Posted Date
- 2013-02-21
- Lead Sponsor
- Pierre Fabre Medicament
- Registration Number
- NCT01469507
Safety Study of Use of Hyaluronic Acid Gel To Prevent Intrauterine Adhesions In Hysteroscopic Surgery
- First Posted Date
- 2011-11-03
- Last Posted Date
- 2011-11-03
- Lead Sponsor
- Hadassah Medical Organization
- Target Recruit Count
- 10
- Registration Number
- NCT01464528
Intra-Articular Autologous Bone Marrow Mesenchymal Stem Cells Transplantation to Treat Mild to Moderate Osteoarthritis
- Conditions
- Interventions
- First Posted Date
- 2011-10-25
- Last Posted Date
- 2011-10-25
- Lead Sponsor
- National University of Malaysia
- Target Recruit Count
- 50
- Registration Number
- NCT01459640
- Locations
- 🇲🇾
UKM Medical Centre, Kuala Lumpur, Malaysia
Hydroxypropylmethylcellulose 0.3% and Sodium Hyaluronate 0.18% for Ocular Surface Disease in Glaucoma
- Conditions
- Interventions
- First Posted Date
- 2011-01-27
- Last Posted Date
- 2011-01-27
- Lead Sponsor
- Mahidol University
- Target Recruit Count
- 120
- Registration Number
- NCT01284439
- Locations
- 🇹🇭
Department of Ophthalmology , Siriraj Hospital, Bangkok, Thailand
Platelet Rich Plasma (PRP) as a Treatment for Knee Osteoarthritis PRP as a Treatment for Knee Osteoarthritis
- Conditions
- Interventions
- First Posted Date
- 2011-01-05
- Last Posted Date
- 2011-07-19
- Lead Sponsor
- Meir Medical Center
- Target Recruit Count
- 100
- Registration Number
- NCT01270412
- Locations
- 🇮🇱
Meir Medical Center, Kfar-Saba, Israel
Intra-articular Hyaluronic Acid in Mild to Moderate Knee Osteoarthritis
- First Posted Date
- 2010-11-11
- Last Posted Date
- 2010-12-09
- Lead Sponsor
- Technical University of Munich
- Target Recruit Count
- 34
- Registration Number
- NCT01239810
A Phase II, Dose Ranging Study Of CP-690,550 Eye Drops In Patients With Dry Eye Disease
- Conditions
- Interventions
- First Posted Date
- 2010-06-02
- Last Posted Date
- 2013-05-07
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 285
- Registration Number
- NCT01135511
- Locations
- 🇰🇷
Pfizer Investigational Site, Seoul, Korea, Republic of
Safety and Efficacy Study of MSB-CAR001 in Subjects 6 Weeks Post an Anterior Cruciate Ligament Reconstruction
- Conditions
- Interventions
- First Posted Date
- 2010-03-17
- Last Posted Date
- 2018-08-15
- Lead Sponsor
- Mesoblast, Ltd.
- Target Recruit Count
- 17
- Registration Number
- NCT01088191
- Locations
- 🇦🇺
Emeritus Research, Malvern East, Victoria, Australia
Effect of Autologous Peripheral Blood Stem Cell Treatment on Articular Cartilage Regeneration
- Conditions
- Interventions
- First Posted Date
- 2010-02-26
- Last Posted Date
- 2015-03-17
- Lead Sponsor
- Kuala Lumpur Sports Medicine Centre
- Target Recruit Count
- 50
- Registration Number
- NCT01076673
- Locations
- 🇲🇾
Kuala Lumpur Sports Medicine Centre, Kuala Lumpur, Malaysia
Drug Development Updates
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