Amiodarone
- Generic Name
- Amiodarone
- Brand Names
- Nexterone, Pacerone
- Drug Type
- Small Molecule
- Chemical Formula
- C25H29I2NO3
- CAS Number
- 1951-25-3
- Unique Ingredient Identifier
- N3RQ532IUT
- Background
Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. Because of its ability to cause serious toxicity and possibly death, amiodarone use s...
- Indication
The FDA approved indications for amiodarone are recurrent ventricular fibrillation (VF) and recurrent hemodynamically unstable ventricular tachycardia (VT). The FDA emphasizes that this drug should only be given in these conditions when they are clinically documented and have not responded to normal therapeutic doses of other antiarrhythmic agents, or when o...
- Associated Conditions
- Atrial Fibrillation, Supraventricular Tachycardia (SVT), Recurrent Ventricular fibrillation, Recurrent hemodynamically unstable Ventricular tachycardia
- Associated Therapies
- -
Amiodarone Prophylaxis for Atrial Fibrillation in Patients Undergoing Surgery for Lung Cancer
- First Posted Date
- 2008-07-29
- Last Posted Date
- 2008-07-29
- Lead Sponsor
- Aarhus University Hospital
- Target Recruit Count
- 275
- Registration Number
- NCT00724581
- Locations
- 🇩🇰
Aarhus University Hospital, Skejby, Aarhus, Denmark
Effect of Prophylaxy of Amiodarone and Propranolol and Amiodarone With Propranolol in Prevention of Atrial Fibrillation Post Coronary Artery Bypass Graft
- Conditions
- Interventions
- First Posted Date
- 2008-04-07
- Last Posted Date
- 2008-04-07
- Lead Sponsor
- Shiraz University of Medical Sciences
- Target Recruit Count
- 240
- Registration Number
- NCT00654290
- Locations
- 🇮🇷
Shiraz University of Medical Sciences/Cardiac Surgery and Cardiology Ward/Namazi and Shahid Faghihi Hospital, Shiraz, Fars, Iran, Islamic Republic of
Amiodarone for the Prevention of Reperfusion Ventricular Fibrillation
- Conditions
- Interventions
- First Posted Date
- 2008-01-07
- Last Posted Date
- 2011-08-11
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 342
- Registration Number
- NCT00587483
- Locations
- 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States
Efficacy & Safety of Dronedarone Versus Amiodarone for the Maintenance of Sinus Rhythm in Patients With Atrial Fibrillation
- Conditions
- Interventions
- First Posted Date
- 2007-06-21
- Last Posted Date
- 2010-02-18
- Lead Sponsor
- Sanofi
- Target Recruit Count
- 504
- Registration Number
- NCT00489736
- Locations
- 🇹🇷
Sanofi-Aventis Administrative Office, Istanbul, Turkey
Relative Bioavailability of PM101 IV and Cordarone IV
- Conditions
- First Posted Date
- 2007-01-11
- Last Posted Date
- 2017-09-08
- Lead Sponsor
- Prism Pharmaceuticals
- Registration Number
- NCT00420953
- Locations
- 🇨🇦
Anapharm, Montreal, Quebec, Canada
Prevention of Atrial Fibrillation Following Esophagectomy
- Conditions
- Interventions
- First Posted Date
- 2007-01-09
- Last Posted Date
- 2013-09-18
- Lead Sponsor
- Indiana University
- Target Recruit Count
- 80
- Registration Number
- NCT00420017
- Locations
- 🇺🇸
Indiana University Hospital, Indianapolis, Indiana, United States
Continuous Versus Episodic Amiodarone Treatment for the Prevention of Permanent Atrial Fibrillation
- Conditions
- First Posted Date
- 2006-10-26
- Last Posted Date
- 2007-03-22
- Lead Sponsor
- University Medical Center Groningen
- Target Recruit Count
- 220
- Registration Number
- NCT00392431
- Locations
- 🇳🇱
University Medical Center Groningen, Groningen, Netherlands
High Intensity Focused Ultrasound (HIFU) Ablation System Study
- Conditions
- Interventions
- First Posted Date
- 2006-10-25
- Last Posted Date
- 2008-06-17
- Lead Sponsor
- ProRhythm, Inc.
- Target Recruit Count
- 240
- Registration Number
- NCT00392106
- Locations
- 🇺🇸
Piedmont Hospital, Atlanta, Georgia, United States
🇺🇸Lahey Clinic, Burlington, Massachusetts, United States
🇺🇸Stony Brook University Hospital, Stony Brook, New York, United States
Study of Amiodarone Given Before Lung Surgery to Prevent Atrial Fibrillation After Lung Resection
- Conditions
- Interventions
- First Posted Date
- 2006-03-09
- Last Posted Date
- 2017-04-28
- Lead Sponsor
- Beth Israel Deaconess Medical Center
- Target Recruit Count
- 19
- Registration Number
- NCT00300495
- Locations
- 🇺🇸
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
Reduction of Atrial Fibrillation Study in Patients Undergoing Coronary Artery Bypass Grafting. (RASCABG 1 Study)
- Conditions
- First Posted Date
- 2006-02-06
- Last Posted Date
- 2006-02-06
- Lead Sponsor
- University of Aarhus
- Target Recruit Count
- 250
- Registration Number
- NCT00287209
- Locations
- 🇩🇰
Department of Cardiothoracic and Vascular Surgery & Institute of Clinical Medicine, Skejby Sygehus, Aarhus University Hospital, Aarhus N, Denmark
Drug Development Updates
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