Histamine
- Generic Name
- Histamine
- Brand Names
- Activon Arthritis, Ceplene, Rematex
- Drug Type
- Small Molecule
- Chemical Formula
- C5H9N3
- CAS Number
- 51-45-6
- Unique Ingredient Identifier
- 820484N8I3
- Background
A depressor amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
- Indication
Histamine phosphate is indicated as a diagnostic aid for the evaluation of gastric acid secretory function.
- Associated Conditions
- Migraine
- Associated Therapies
- -
Evaluation of Peripheral Itch Mechanisms Following Injection of Morphine (Second Sub-Project)
- Conditions
- Interventions
- First Posted Date
- 2021-01-07
- Last Posted Date
- 2022-01-27
- Lead Sponsor
- Aalborg University
- Target Recruit Count
- 26
- Registration Number
- NCT04700007
- Locations
- 🇩🇰
Mech-Sense, Medicinsk Gastroenterologisk ambulatorium, Medicineshus, Aalborn Universitethospitalet, AAlborg, Nordjylland, Denmark
Substance P Challenge in Healthy Participants
- Conditions
- Interventions
- First Posted Date
- 2020-12-21
- Last Posted Date
- 2024-02-08
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 32
- Registration Number
- NCT04676763
- Locations
- 🇳🇱
GSK Investigational Site, Leiden, Netherlands
Characterization of BAM8-22 as a New Surrogate Model of Non-histaminergic Itch
- Conditions
- Interventions
- First Posted Date
- 2020-10-19
- Last Posted Date
- 2021-07-21
- Lead Sponsor
- Aalborg University
- Target Recruit Count
- 24
- Registration Number
- NCT04588532
- Locations
- 🇩🇰
Aalborg University, Aalborg, Denmark
Characterization of New Human Models of Non-histaminergic Itch and Their Interaction With the TRPM8 Receptor
- Conditions
- Interventions
- First Posted Date
- 2020-09-18
- Last Posted Date
- 2022-07-20
- Lead Sponsor
- Aalborg University
- Target Recruit Count
- 20
- Registration Number
- NCT04554888
- Locations
- 🇩🇰
Aalborg University, Aalborg, Nordjylland, Denmark
A Relation of Morphine-induced Itch and Pain Processing
- Conditions
- Interventions
- First Posted Date
- 2019-10-04
- Last Posted Date
- 2020-07-08
- Lead Sponsor
- Aalborg University
- Target Recruit Count
- 24
- Registration Number
- NCT04115462
- Locations
- 🇩🇰
Mech-Sense, Medicinsk Gastroenterologisk ambulatorium, Medicineshus, Aalborg Universitetshospitalet,, AAlborg, Nordjylland, Denmark
Skin Prick Test of KeraStat® Cream
- Conditions
- Interventions
- First Posted Date
- 2019-08-15
- Last Posted Date
- 2022-11-15
- Lead Sponsor
- KeraNetics, LLC
- Target Recruit Count
- 22
- Registration Number
- NCT04058054
- Locations
- 🇺🇸
PMG Research, Inc., Winston-Salem, North Carolina, United States
Leukotriene D4 Nasal Provocation Test in Allergic Rhinitis
- Conditions
- Interventions
- First Posted Date
- 2013-10-16
- Last Posted Date
- 2015-07-09
- Lead Sponsor
- Guangzhou Institute of Respiratory Disease
- Target Recruit Count
- 60
- Registration Number
- NCT01963741
- Locations
- 🇨🇳
Guangzhou institute of respiratory disease, Guangzhou, Guangdong, China
Skin Prick Tests With AllerT in Subjects Allergic to Birch Pollen
- First Posted Date
- 2012-11-01
- Last Posted Date
- 2012-11-01
- Lead Sponsor
- Anergis
- Target Recruit Count
- 20
- Registration Number
- NCT01719133
- Locations
- 🇨🇭
Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
Evaluation of the Allergenicity of AMPHADASE INJECTION (Hyaluronidase Injection USP)
- Conditions
- Interventions
- First Posted Date
- 2012-09-21
- Last Posted Date
- 2017-01-20
- Lead Sponsor
- Amphastar Pharmaceuticals, Inc.
- Target Recruit Count
- 253
- Registration Number
- NCT01689363
- Locations
- 🇺🇸
Amphastar Site 0026, Portland, Oregon, United States
🇺🇸Amphastar Site 0038, Renton, Washington, United States
🇺🇸Amphastar Site 0022, Eugene, Oregon, United States
An Evaluation of the Efficacy and Safety of TOLAMBA™ for Ragweed-Allergic Rhinitis in an Environmental Exposure Chamber
- Conditions
- Interventions
- First Posted Date
- 2007-10-01
- Last Posted Date
- 2019-04-16
- Lead Sponsor
- Dynavax Technologies Corporation
- Target Recruit Count
- 271
- Registration Number
- NCT00537355
- Locations
- 🇨🇦
Allied Research International Inc., Mississauga, Ontario, Canada
🇨🇦Allergy & Asthma Research Centre, Ottawa, Ontario, Canada
🇨🇦Alpha Medical Research Inc., Mississauga, Ontario, Canada
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.