Morphine
- Generic Name
- Morphine
- Brand Names
- Arymo, Avinza, Doloral, Duramorph, Embeda, Infumorph, Kadian, M-ediat, M-eslon, MSIR, Mitigo, Ms Contin, Statex
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19NO3
- CAS Number
- 57-27-2
- Unique Ingredient Identifier
- 76I7G6D29C
- Background
Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as codeine, fentanyl, methadone, hydrocodone, hydromorphone, meperidine, and oxycodone.
Morphine was granted FDA approval in 1941.
- Indication
Morphine is used for the management of chronic, moderate to severe pain.
Opiods, including morphine, are effective for the short term management of pain. Patients taking opioids long term may need to be monitored for the development of physical dependence, addiction disorder, and drug abuse.
- Associated Conditions
- Chronic Pain, Severe Pain
- Associated Therapies
- -
Is Analgesic Effect of Low Dose Ketamine-midazolam the Same as Morphine
- Conditions
- Interventions
- First Posted Date
- 2013-03-08
- Last Posted Date
- 2013-03-08
- Lead Sponsor
- Isfahan University of Medical Sciences
- Target Recruit Count
- 236
- Registration Number
- NCT01807429
Comparison Between Methadone and Morphine for Neonatal Opiate Withdrawal
- First Posted Date
- 2013-03-05
- Last Posted Date
- 2017-09-28
- Lead Sponsor
- Eastern Maine Medical Center
- Target Recruit Count
- 31
- Registration Number
- NCT01804075
Mechanisms of Sleep Disruption Hyperalgesia
- Conditions
- Interventions
- First Posted Date
- 2013-02-20
- Last Posted Date
- 2019-08-02
- Lead Sponsor
- Johns Hopkins University
- Target Recruit Count
- 100
- Registration Number
- NCT01794689
- Locations
- 🇺🇸
Johns Hopkins University Bayview Medical Center, Baltimore, Maryland, United States
Altered Drug Disposition and Biomarkers for Diagnosis of Chronic Inflammatory Liver Disease
- First Posted Date
- 2013-01-11
- Last Posted Date
- 2016-03-03
- Lead Sponsor
- University of North Carolina, Chapel Hill
- Target Recruit Count
- 22
- Registration Number
- NCT01766960
- Locations
- 🇺🇸
North Carolina Clinical and Translational Research Center, Chapel Hill, North Carolina, United States
Inflammatory Responses to Acute and Chronic Opioid Exposure in Humans
- First Posted Date
- 2012-12-17
- Last Posted Date
- 2019-01-30
- Lead Sponsor
- Stanford University
- Target Recruit Count
- 20
- Registration Number
- NCT01749826
- Locations
- 🇺🇸
Stanford University School of Medicine, Stanford, California, United States
Ticagrelor and Intracoronary Morphine in Patients Undergoing Primary Percutaneous Coronary Intervention
- Conditions
- Interventions
- First Posted Date
- 2012-11-30
- Last Posted Date
- 2016-07-06
- Lead Sponsor
- Hyeon-Cheol Gwon
- Target Recruit Count
- 100
- Registration Number
- NCT01738100
- Locations
- 🇰🇷
Samsung Medical Center, Seoul, Gang nam-Gu, Ilwon-Dong, Korea, Republic of
NAS Treatment - Opiate Versus Non-Opiate
- First Posted Date
- 2012-11-27
- Last Posted Date
- 2017-09-12
- Lead Sponsor
- Henrietta Bada
- Target Recruit Count
- 31
- Registration Number
- NCT01734551
- Locations
- 🇺🇸
University of Kentucky Medical Center, Lexington, Kentucky, United States
Morphine, Dyspnea, Exercise and COPD
- First Posted Date
- 2012-10-31
- Last Posted Date
- 2015-09-24
- Lead Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
- Target Recruit Count
- 20
- Registration Number
- NCT01718496
- Locations
- 🇨🇦
Montreal Chest Institute, Montreal, Quebec, Canada
Comparison of Buprenorphine to Morphine in Treatment of Neonatal Abstinence Syndrome (NAS)
- Conditions
- Interventions
- First Posted Date
- 2012-10-17
- Last Posted Date
- 2018-08-15
- Lead Sponsor
- Pediatrix
- Target Recruit Count
- 29
- Registration Number
- NCT01708707
- Locations
- 🇺🇸
Banner - University Medical Center Phoenix, Phoenix, Arizona, United States
Analgesic Effect of IV Acetaminophen in Tonsillectomies
- First Posted Date
- 2012-09-25
- Last Posted Date
- 2017-04-06
- Lead Sponsor
- Nationwide Children's Hospital
- Target Recruit Count
- 250
- Registration Number
- NCT01691690
- Locations
- 🇺🇸
Nationwide Children's Hospital, Columbus, Ohio, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.