Vindesine

Generic Name
Vindesine
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C43H55N5O7
CAS Number
53643-48-4
Unique Ingredient Identifier
RSA8KO39WH
Background

Vinblastine derivative with antineoplastic activity against cancer. Major side effects are myelosuppression and neurotoxicity. Vindesine is used extensively in chemotherapy protocols (antineoplastic combined chemotherapy protocols).

Indication

For the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia and acute panmyelosis

Associated Conditions
Acute Lymphoblastic Leukemia (ALL), Blast crisis in myelogenous leukaemia, Malignant Melanoma
Associated Therapies
-

Trial of R-GemOx Versus R-miniCHOP Regimen in First-line Treatment of Elderly Diffuse Large B Cell Lymphoma

First Posted Date
2016-05-10
Last Posted Date
2019-01-03
Lead Sponsor
The First Affiliated Hospital with Nanjing Medical University
Target Recruit Count
258
Registration Number
NCT02767674
Locations
๐Ÿ‡จ๐Ÿ‡ณ

Shandong Province Hospital, Jinan, Shandong, China

๐Ÿ‡จ๐Ÿ‡ณ

Tongji Medical College of HUST, Wuhan, Hubei, China

๐Ÿ‡จ๐Ÿ‡ณ

The first Affiliated Hospital Of Nanjing Medical University(JiangSu Province Hospital), NanJing, Jiangsu, China

and more 3 locations

Combination Chemotherapy in Treating Young Adult Patients With Acute Lymphoblastic Leukemia

Not Applicable
Completed
Conditions
First Posted Date
2010-07-05
Last Posted Date
2021-09-13
Lead Sponsor
Gruppo Italiano Malattie EMatologiche dell'Adulto
Target Recruit Count
76
Registration Number
NCT01156883
Locations
๐Ÿ‡ฎ๐Ÿ‡น

Azienda Ospedaliera - Nuovo Ospedale "Torrette", Ancona, Italy

๐Ÿ‡ฎ๐Ÿ‡น

USL 8 - Ospedale S.Donato, Arezzo, Italy

๐Ÿ‡ฎ๐Ÿ‡น

UO Ematologia con trapianto- AOU Policlinico Consorziale di Bari, Bari, Italy

and more 40 locations

International Collaborative Treatment Protocol For Children And Adolescents With Acute Lymphoblastic Leukemia

First Posted Date
2010-05-05
Last Posted Date
2022-05-24
Lead Sponsor
University Hospital Schleswig-Holstein
Target Recruit Count
6136
Registration Number
NCT01117441
Locations
๐Ÿ‡ฆ๐Ÿ‡น

A.oe. Landeskrankenhaus Klagenfurt, Abt. fรผr Kinder- und Jugendheilkunde, Klagenfurt, Austria

๐Ÿ‡จ๐Ÿ‡ฟ

University Hospital Brno, Department of Pediatric Oncology, Brno, Czechia

๐Ÿ‡ฉ๐Ÿ‡ช

Klinikum Berlin-Buch II. Kinderklinik, Bereich Onkologie/Allg. Pรคdiatrie, Berlin, Germany

and more 134 locations

Combination Chemotherapy and Rituximab in Treating Patients With Primary Mediastinal Diffuse Large B-Cell Lymphoma

First Posted Date
2008-06-04
Last Posted Date
2009-07-08
Lead Sponsor
University Hospital Southampton NHS Foundation Trust
Target Recruit Count
120
Registration Number
NCT00689845
Locations
๐Ÿ‡ฌ๐Ÿ‡ง

Leeds Cancer Centre at St. James's University Hospital, Leeds, England, United Kingdom

๐Ÿ‡ฌ๐Ÿ‡ง

Christie Hospital, Manchester, England, United Kingdom

๐Ÿ‡ฌ๐Ÿ‡ง

Southampton General Hospital, Southampton, England, United Kingdom

and more 5 locations

Combination Chemotherapy Followed by Stem Cell Transplant and Isotretinoin in Treating Young Patients With High-Risk Neuroblastoma

Not Applicable
Conditions
First Posted Date
2007-09-10
Last Posted Date
2015-07-16
Lead Sponsor
German Society for Pediatric Oncology and Hematology GPOH gGmbH
Target Recruit Count
360
Registration Number
NCT00526318
Locations
๐Ÿ‡ฉ๐Ÿ‡ช

Klinikum Augsburg, Augsburg, Germany

๐Ÿ‡ฉ๐Ÿ‡ช

Evangelisches Krankenhauus Bielfeld, Biefeld, Germany

๐Ÿ‡ฉ๐Ÿ‡ช

Klinikum Duisburg, Duisburg, Germany

and more 64 locations

Combination Chemotherapy Based on Risk of Relapse in Treating Young Patients With Acute Lymphoblastic Leukemia

First Posted Date
2007-02-01
Last Posted Date
2013-05-29
Lead Sponsor
University Hospital Schleswig-Holstein
Target Recruit Count
4559
Registration Number
NCT00430118
Locations
๐Ÿ‡ฆ๐Ÿ‡น

LKH Leoben, Leoben, Austria

๐Ÿ‡ฆ๐Ÿ‡น

Landeskrankenhaus Feldkirch, Feldkirch-Tisis, Austria

๐Ÿ‡ฆ๐Ÿ‡น

Universitaet Kinderklinik, Graz, Austria

and more 72 locations

Observation, Combination Chemotherapy, Radiation Therapy, and/or Autologous Stem Cell Transplant in Treating Young Patients With Neuroblastoma

Phase 3
Conditions
First Posted Date
2006-12-13
Last Posted Date
2013-08-07
Lead Sponsor
German Society for Pediatric Oncology and Hematology GPOH gGmbH
Target Recruit Count
642
Registration Number
NCT00410631
Locations
๐Ÿ‡ฉ๐Ÿ‡ช

Kinderklinik - Universitaetsklinikum Aachen, Aachen, Germany

๐Ÿ‡ฉ๐Ÿ‡ช

Klinikum Dortmund, Dortmund, Germany

๐Ÿ‡ฉ๐Ÿ‡ช

Kliniken der Stadt Koeln gGmbH - Kinderkrankenhaus Riehl, Cologne, Germany

and more 74 locations
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