Fluticasone propionate

Generic Name
Fluticasone propionate
Brand Names
Advair, Airduo, Airduo Respiclick, Aller-flo, Armonair, Beser, Cutivate, Dymista, Flonase, Flovent, Fluticare, Ticanase, Wixela, Xhance
Drug Type
Small Molecule
Chemical Formula
C25H31F3O5S
CAS Number
80474-14-2
Unique Ingredient Identifier
O2GMZ0LF5W
Background

Fluticasone propionate is a synthetic glucocorticoid. These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications. Fluticasone propionate was first approved in 1990.

Indication

Fluticasone propionate is indicated as an inhaler for the treatment and management of asthma by prophylaxisas well as inflammatory and pruritic dermatoses. Fluticasone propionate nasal spray is indicated for managing allergic and nonallergic rhinitis.

Associated Conditions
Allergic Rhinitis (AR), Allergy to Animal Dander, Allergy to Mold, Allergy to Tree Pollen, Asthma, Bacterial Sinusitis, Chronic Bronchitis, Chronic Obstructive Pulmonary Disease (COPD), Chronic Sinusitis, Dermatitis, Emphysema, Eosinophilic Esophagitis, House Dust Mite Allergy, House dust allergy, Itching of the nose, Nasal Congestion, Non-Allergic Rhinitis, Rhinitis, Rhinitis Perennial, Rhinorrhoea, Seasonal Allergic Rhinitis, Sneezing, Moderate, severe Perennial Allergic Rhinitis (PAR), Moderate, severe Seasonal Allergic Rhinitis
Associated Therapies
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A Study to Evaluate the Safety and Effectiveness of a Nasal Spray to Treat Seasonal Allergies

First Posted Date
2008-04-17
Last Posted Date
2012-07-27
Lead Sponsor
Meda Pharmaceuticals
Target Recruit Count
607
Registration Number
NCT00660517
Locations
🇺🇸

Southwest Allergy and Asthma Center, P.A., San Antonio, Texas, United States

🇺🇸

Allergy and Asthma Care, Waco, Texas, United States

🇺🇸

Sylvana Research Associates, San Antonio, Texas, United States

and more 4 locations

Inhaled Corticosteroids Versus Observation for Patients With Decreased Lung Function Status

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2008-04-11
Last Posted Date
2012-04-23
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
1
Registration Number
NCT00656916
Locations
🇺🇸

UT MD Anderson Cancer Center, Houston, Texas, United States

A Comparison of Olopatadine and Fluticasone in Patients With Allergic Conjunctivitis

First Posted Date
2008-04-09
Last Posted Date
2008-04-09
Lead Sponsor
Greiner, Jack V., OD DO PhD
Target Recruit Count
60
Registration Number
NCT00655109
Locations
🇺🇸

Ophthalmic Research Associates, Inc, North Andover, Massachusetts, United States

A Study to Evaluate the Safety and Effectiveness of a Nasal Spray to Treat Seasonal Allergies

First Posted Date
2008-04-02
Last Posted Date
2012-09-26
Lead Sponsor
Meda Pharmaceuticals
Target Recruit Count
832
Registration Number
NCT00651118
Locations
🇺🇸

Jane Lee, MD, PA Research Center, Dallas, Texas, United States

🇺🇸

Allergy Research Foundation, Los Angeles, California, United States

🇺🇸

Asthma, Inc., Seattle, Washington, United States

and more 36 locations

Rhinocort Aqua Versus Placebo and Fluticasone Propionate

First Posted Date
2008-03-24
Last Posted Date
2011-01-24
Lead Sponsor
AstraZeneca
Target Recruit Count
750
Registration Number
NCT00641680

A Phase II Study Evaluating Intranasal GSK256066 and Fluticasone Propionate in Subjects With Seasonal Allergic Rhinitis (SAR)

Phase 2
Completed
Conditions
First Posted Date
2008-02-12
Last Posted Date
2016-11-03
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
55
Registration Number
NCT00612820
Locations
🇦🇹

GSK Investigational Site, Vienna, Austria

Dose Response Effects of Inhaled Fluticasone on Airway Effects of Hypertonic-saline in Asthma

Phase 4
Completed
Conditions
Interventions
First Posted Date
2008-02-01
Last Posted Date
2014-03-10
Lead Sponsor
University of California, San Francisco
Target Recruit Count
44
Registration Number
NCT00606242
Locations
🇺🇸

University of California, San Francisco, San Francisco, California, United States

Leukotriene Receptor Antagonists or Steroids in Pre-School Asthma

Phase 2
Completed
Conditions
Interventions
First Posted Date
2007-10-15
Last Posted Date
2009-02-04
Lead Sponsor
Johann Wolfgang Goethe University Hospital
Target Recruit Count
100
Registration Number
NCT00543686
Locations
🇩🇪

Goethe University, Department of Pulmonology, Frankfurt, Hessen, Germany

Efficacy and Safety Comparison of Steroid or Placebo in Combination With Salmeterol and Tiotropium in COPD

First Posted Date
2007-09-26
Last Posted Date
2014-05-30
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
103
Registration Number
NCT00535366
Locations
🇧🇪

1249.1.32002 Boehringer Ingelheim Investigational Site, Hasselt, Belgium

🇧🇪

1249.1.32001 Boehringer Ingelheim Investigational Site, Gent, Belgium

🇳🇱

1249.1.31003 Boehringer Ingelheim Investigational Site, Harderwijk, Netherlands

and more 9 locations
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