Lidocaine

Generic Name: Lidocaine

Brand Names: Agoneaze, Akten, Alivio, Anestacon, Anodyne Lpt, Astero, Band-aid Hurt-free, Cathejell, Curacaine, Depo-medrol With Lidocaine, Dermacinrx Lido V Pak, Dermacinrx Phn Pak, Dermacinrx Prikaan, Diphen, Emla, Fortacin, Glydo, Instillagel, Kenalog, Lido Bdk, Lido-prilo Caine Pack, Lidocan, Lidodan, Lidoderm, Lidopac, Lidopril, Lidopro, Lidosol, Lidothol, Lidotral, Lignospan, Marcaine, Max-freeze, Medi-derm With Lidocaine, Neo-bex, Octocaine, Octocaine With Epinephrine, Oraqix, P-care, P-care X, Pliaglis, Prilolid, Prizotral, Procomycin, Readysharp Anesthetics Plus Ketorolac, Readysharp-A, Readysharp-p40, Readysharp-p80, Relador, Synera, Triple Antibiotic, Venipuncture Px1, Viadur, Xylocaine, Xylocaine With Epinephrine, Xylocard, Xylonor, Zingo, Ztlido

Drug Type: Small Molecule

Chemical Formula: C_₁₄H_₂₂N_₂O

CAS Number: 137-58-6

Unique Ingredient Identifier: 98PI200987

Background: Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication . In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local anesthesia for a large variety of surgical p...

Indication: Lidocaine is an anesthetic of the amide group indicated for production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks .

Associated Conditions: Acute Otitis Media (AOM), Anorectal discomfort, Arrhythmia, Back Pain Lower Back, Bacterial Vaginosis (BV), Burns, Cervical Syndrome, Earache, Fissure;Anal, Haemorrhoids, Infection, Inflammatory Reaction caused by ear infection-not otherwise specified, Insect Bites, Joint Pain, Mixed Vaginal Infections, Multiple Myeloma (MM), Myringitis, Neuritis, Osteolysis caused by Bone Tumors, Osteoporosis, Otitis Externa, Pain caused by ear infection-not otherwise specified, Pain, Inflammatory, Postherpetic Neuralgia, Primary Hyperparathyroidism (PHPT), Rheumatic Diseases, Rheumatic Joint Disease, Sciatica, Skin Irritation, Soft Tissue Inflammation, Sore Throat, Sunburn, Susceptible infections, Trichomonas Vaginitis, Ulcers, Leg, Urethral Strictures, Ventricular Arrhythmia, Vulvovaginal Candidiasis, Abrasions, Anal discomfort, Cutaneous lesions, Gum pain, Minor burns, Superficial Wounds, Susceptible Bacterial Infections, Ulceration of the mouth, Viral infections of the external ear canal

Associated Therapies: Local Anaesthesia therapy, Post Myocardial Infarction Treatment, Regional Anesthesia therapy

Clinical Trials

The Effect of Intravenous Lidocaine on Normal Sensation and Pain in Healthy Volunteers

Not Applicable

Completed

Conditions: Pain

Interventions: Drug: Lidocaine

First Posted Date: 2008-04-14

Last Posted Date: 2017-05-17

Lead Sponsor: University of Alabama at Birmingham

Target Recruit Count: 22

Registration Number: NCT00657358

Locations: 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States

Preemptive Analgesia for Postlaminectomy

Phase 4

Completed

Conditions: Laminectomy

Interventions: Drug: Lidocaine, perineural injection, intraoperatively
Drug: Lidocaine

First Posted Date: 2008-04-11

Last Posted Date: 2008-04-11

Lead Sponsor: Harran University

Target Recruit Count: 40

Registration Number: NCT00656526

Locations: 🇹🇷
harran University Education, Research and application hospital, Sanliurfa, Turkey

Efficacy and Safety Study of Lidocaine Vaginal Gel for Recurrent Dysmenorrhea (Painful Periods)

Phase 2

Completed

Conditions: Dysmenorrhea

Interventions: Drug: Placebo
Drug: Lidocaine

First Posted Date: 2008-04-02

Last Posted Date: 2012-02-17

Lead Sponsor: Juniper Pharmaceuticals, Inc.

Target Recruit Count: 81

Registration Number: NCT00651313

Locations: 🇺🇸
Lyndhurst Gynecologic Associates, Winston-Salem, North Carolina, United States
🇺🇸
SCIREX Research Center, Austin, Texas, United States
🇺🇸
Jean Brown Research, Salt Lake City, Utah, United States

Lidocaine Injection and Ischemic Compression on Chronic Pelvic Pain Treatment

Phase 4

Terminated

Conditions: Pelvic Pain

Interventions: Procedure: Ischemic compression
Drug: lidocaine

First Posted Date: 2008-03-05

Last Posted Date: 2014-06-06

Lead Sponsor: University of Sao Paulo

Target Recruit Count: 30

Registration Number: NCT00628355

Locations: 🇧🇷
Center of Chronic Pelvic Pain and Gynecologic Endoscopy of Ribeirao Preto Medical School, University of Sao Paulo, Ribeirão Preto, Sao Paulo, Brazil

Treatment of Postoperative Pain After Total Knee Arthroplasy Using Intravenous Lidocaine Infusion

Not Applicable

Withdrawn

Conditions: Total Knee Arthroplasty

Interventions: Drug: Lidocaine
Other: Preservative free normal saline
Procedure: Continuous femoral catheter block

First Posted Date: 2008-02-15

Last Posted Date: 2014-05-22

Lead Sponsor: Loma Linda University

Registration Number: NCT00616850

Locations: 🇺🇸
Loma Linda University Medical Center, Loma Linda, California, United States

Paracervical Block in First Trimester Surgical Abortions

Phase 2

Completed

Conditions: Pain
Surgical Abortion

Interventions: Drug: ketorolac and lidocaine
Drug: lidocaine

First Posted Date: 2008-02-15

Last Posted Date: 2017-09-15

Lead Sponsor: Johns Hopkins University

Target Recruit Count: 50

Registration Number: NCT00617097

Locations: 🇺🇸
Planned Parenthood Columbia-Willamette, Portland, Oregon, United States

Lidocaine and Pain Management in First Trimester Abortions

Not Applicable

Completed

Conditions: Pain

Interventions: Drug: Lidocaine

First Posted Date: 2008-02-13

Last Posted Date: 2017-07-31

Lead Sponsor: Oregon Health and Science University

Target Recruit Count: 80

Registration Number: NCT00613821

Locations: 🇺🇸
Planned Parenthood of the Columbia Willamette, Portland, Oregon, United States
🇺🇸
Oregon Health and Science University, Portland, Oregon, United States

Intrauterine Lidocaine Infusion for Essure Sterilization Procedures

Phase 4

Completed

Conditions: Pain

Interventions: Drug: Lidocaine
Drug: Sterile Saline

First Posted Date: 2008-02-13

Last Posted Date: 2019-12-19

Lead Sponsor: Oregon Health and Science University

Target Recruit Count: 58

Registration Number: NCT00613834

Locations: 🇺🇸
Planned Parenthood of the Columbia Willamette, Portland, Oregon, United States
🇺🇸
Oregon Health & Science University, Portland, Oregon, United States