Fluconazole
- Generic Name
- Fluconazole
- Brand Names
- Diflucan
- Drug Type
- Small Molecule
- Chemical Formula
- C13H12F2N6O
- CAS Number
- 86386-73-4
- Unique Ingredient Identifier
- 8VZV102JFY
- Background
Fluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole has many advantages over the other antifungal dr...
- Indication
Fluconazole can be administered in the treatment of the following fungal infections:
1) Vaginal yeast infections caused by Candida
2) Systemic Candida infections
3) Both esophageal and oropharyngeal candidiasis
4) Cryptococcal meningitis
5) UTI (urinary tract infection) by Candida
6) Peritonitis (inflammation of the peritoneum) caused by Candida
...
- Associated Conditions
- Candida intertrigo, Candida pneumonia, Candida urinary tract infection, Candidemia, Candidiasis, Coccidioidomycosis, Esophageal Candidiasis, Fungal Infections, Fungal peritonitis caused by Candida, Meningitis, Cryptococcal, Oropharyngeal Candidiasis, Peritoneal candidiasis, Pneumonia cryptococcal, Pruritus, Skin Irritation, Systemic Candida Infections caused by Candida, Vaginal Candidiasis, Disseminated Candidiasis
- Associated Therapies
- -
Comparing the Effectiveness of Fluconazole and a New Medicine (FK463) in Preventing Fungal Infections in Bone Marrow Transplant Patients
- Conditions
- First Posted Date
- 2002-12-10
- Last Posted Date
- 2008-03-04
- Lead Sponsor
- National Cancer Institute (NCI)
- Target Recruit Count
- 800
- Registration Number
- NCT00001937
- Locations
- 🇺🇸
National Cancer Institute (NCI), Bethesda, Maryland, United States
Fluconazole Prophylaxis of Thrush in AIDS
- Conditions
- First Posted Date
- 2002-05-22
- Last Posted Date
- 2008-03-04
- Target Recruit Count
- 80
- Registration Number
- NCT00001542
- Locations
- 🇺🇸
National Institute of Allergy and Infectious Diseases (NIAID), Bethesda, Maryland, United States
Blood and Marrow Transplant Clinical Research Network
- Locations
- 🇺🇸
City of Hope National Medical Center, Duarte, California, United States
🇺🇸University of California at San Diego, La Jolla, California, United States
🇺🇸Stanford University, Palo Alto, California, United States
A Study to Compare the Use of Fluconazole as Continuous Therapy Versus Periodic Therapy in HIV-Positive Patients With Recurrent Thrush
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-10-29
- Target Recruit Count
- 948
- Registration Number
- NCT00000951
- Locations
- 🇺🇸
State of MD Div of Corrections / Johns Hopkins Univ Hosp, Baltimore, Maryland, United States
🇺🇸Boston Med Ctr, Boston, Massachusetts, United States
🇺🇸MetroHealth Med Ctr, Cleveland, Ohio, United States
A Randomized Double Blind Protocol Comparing Amphotericin B With Flucytosine to Amphotericin B Alone Followed by a Comparison of Fluconazole and Itraconazole in the Treatment of Acute Cryptococcal Meningitis
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-02
- Target Recruit Count
- 400
- Registration Number
- NCT00000639
- Locations
- 🇺🇸
Ucsf Aids Crs, San Francisco, California, United States
🇺🇸USC CRS, Los Angeles, California, United States
🇺🇸Northwestern University CRS, Chicago, Illinois, United States
Pilot Study to Determine the Feasibility of Fluconazole for Induction Treatment and Suppression of Relapse of Histoplasmosis in Patients With the Acquired Immunodeficiency Syndrome
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-02
- Target Recruit Count
- 90
- Registration Number
- NCT00000627
- Locations
- 🇺🇸
Methodist Hosp of Indiana / Life Care Clinic, Indianapolis, Indiana, United States
🇺🇸San Francisco Veterans Administration Med Ctr, San Francisco, California, United States
🇺🇸Montefiore Med Ctr / Bronx Municipal Hosp, Bronx, New York, United States
Randomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis.
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Janssen Pharmaceuticals
- Registration Number
- NCT00002132
- Locations
- 🇺🇸
Rush Presbyterian - Saint Luke's Med Ctr, Chicago, Illinois, United States
🇺🇸Univ of Missouri at Kansas City School of Medicine, Kansas City, Missouri, United States
🇺🇸Dr Eskild A Petersen, Tucson, Arizona, United States
A Study of Fluconazole in the Treatment of Fungal Infections of the Throat in Patients With Weakened Immune Systems
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 100
- Registration Number
- NCT00002339
- Locations
- 🇺🇸
Houston Veterans Administration Med Ctr, Houston, Texas, United States
🇺🇸Los Angeles County - USC Med Ctr, Los Angeles, California, United States
A Pilot Study of Fluconazole Plus Flucytosine for the Treatment of AIDS Patients With Acute Cryptococcal Meningitis.
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 64
- Registration Number
- NCT00002113
- Locations
- 🇺🇸
UCSD Med Ctr - Owen Clinic, San Diego, California, United States
🇺🇸Los Angeles County - USC Med Ctr, Los Angeles, California, United States
🇺🇸UCI Med Ctr, Orange, California, United States
A Study of Fluconazole in the Treatment of Cryptococcal Meningitis in Patients Who Have Not Had Success With Amphotericin B
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Pfizer
- Registration Number
- NCT00002306
- Locations
- 🇺🇸
Med College of Georgia, Augusta, Georgia, United States
🇺🇸Washington Univ School of Medicine, St. Louis, Missouri, United States
🇺🇸Univ of South Florida, Tampa, Florida, United States
Drug Development Updates
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