Atenolol

Generic Name: Atenolol

Brand Names: Tenoretic, Tenormin

Drug Type: Small Molecule

Chemical Formula: C_₁₄H_₂₂N_₂O_₃

CAS Number: 29122-68-7

Unique Ingredient Identifier: 50VV3VW0TI

Background: Atenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions.
...

Indication: Indicated for:

1) Management of hypertension alone and in combination with other antihypertensives.

2) Management of angina pectoris associated with coronary atherosclerosis.

3) Management of acute myocardial infarction in hemodynamically stable patients with a heart rate greater than 50 beats per minutes and a systolic blood pressure above 100 mmHg.
...

Associated Conditions: Alcohol Withdrawal Syndrome, Angina Pectoris, Atrial Fibrillation, Heart Failure, Hypertension, Migraine, Myocardial Infarction, Refractory Hypertension, Secondary prevention Myocardial infarction, Supra-ventricular Tachyarrhythmias, Thyrotoxicosis, Ventricular Tachyarrhythmias

Associated Therapies: -

Clinical Trials

Genetically Determined Response to Atenolol in Patients With Persistent Atrial Fibrillation

Not Applicable

Completed

Conditions: Atrial Fibrillation

Interventions: Drug: Atenolol

First Posted Date: 2012-11-01

Last Posted Date: 2019-06-17

Lead Sponsor: Vanderbilt University Medical Center

Target Recruit Count: 38

Registration Number: NCT01719367

Locations: 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States

Comparison of Aliskiren vs Negative Controls on Aortic Stiffness in Patients With MFS

Phase 3

Completed

Conditions: Marfan Syndrome

Interventions: Drug: Aliskiren
Drug: Atenolol

First Posted Date: 2012-10-26

Last Posted Date: 2017-06-05

Lead Sponsor: Samsung Medical Center

Target Recruit Count: 30

Registration Number: NCT01715207

Locations: 🇰🇷
Samsung Medical Center, Seoul, Korea, Republic of

A Study Examining the Effects of Nebivolol Compared to Atenolol on Endothelial Function

Phase 2

Completed

Conditions: Hypertension

Interventions: Drug: placebo
Drug: Nebivolol
Drug: atenolol

First Posted Date: 2012-02-01

Last Posted Date: 2020-07-17

Lead Sponsor: University of Minnesota

Target Recruit Count: 76

Registration Number: NCT01522950

Locations: 🇺🇸
University of Minnesota, Minneapolis, Minnesota, United States

Effect of SLCO2B1 Genotype and Apple Juice on Pharmacokinetics of Atenolol After Oral Administration in Healthy Male Korean

Phase 4

Completed

Conditions: Healthy

Interventions: Drug: Atenolol
Drug: Atenolol with apple juice 1200 mL
Drug: Atenolol with apple juice 600 mL

First Posted Date: 2011-10-04

Last Posted Date: 2012-01-23

Lead Sponsor: Seoul National University Hospital

Target Recruit Count: 12

Registration Number: NCT01445964

Locations: 🇰🇷
Seoul National University Hospital, Seoul, Korea, Republic of

Study to Assess Efficacy of Nicorandil+Atenolol vs Atenolol in Treatment of Chronic Stable Angina.

Phase 4

Conditions: Chronic Stable Angina

Interventions: Drug: Nicorandil
Drug: Atenolol

First Posted Date: 2011-07-20

Last Posted Date: 2011-12-08

Lead Sponsor: Ferozsons Laboratories Ltd.

Target Recruit Count: 40

Registration Number: NCT01397994

Locations: 🇵🇰
National Institute of Cardiovascular Diseases, Karachi, Sind, Pakistan

Comparison of Medical Therapies in Marfan Syndrome.

Phase 4

Completed

Conditions: Marfan Syndrome

Interventions: Drug: VERAPAMIL
Drug: Atenolol
Drug: Perindopril

First Posted Date: 2011-02-14

Last Posted Date: 2011-02-14

Lead Sponsor: Cardiff University

Target Recruit Count: 18

Registration Number: NCT01295047

Locations: 🇬🇧
Wales Heart Research Institute, Cardiff University, Cardiff, United Kingdom

A Randomized Controlled Study to Assess the Effects of Bisoprolol and Atenolol on Resting Heart Rate and Sympathetic Nervous System's Activity in Subjects With Essential Hypertension

Phase 4

Completed

Conditions: Hypertension

Interventions: Drug: Bisoprolol
Drug: Atenolol

First Posted Date: 2010-12-01

Last Posted Date: 2017-03-08

Lead Sponsor: Merck KGaA, Darmstadt, Germany

Target Recruit Count: 177

Registration Number: NCT01251146

Locations: 🇨🇳
Beijing Shi Jingshan Hospital, Beijing, China
🇨🇳
Shanghai Institute of Hypertension, Shanghai, China

Evaluation of The Effects of Nebivolol in Comparison to Atenolol on Wall Shear Stress and Rupture Prone Coronary Plaques

Phase 4

Completed

Conditions: Atherosclerosis
Endothelial Function

Interventions: Drug: Nebivolol
Drug: Atenolol

First Posted Date: 2010-10-29

Last Posted Date: 2015-02-27

Lead Sponsor: Emory University

Target Recruit Count: 29

Registration Number: NCT01230892

Locations: 🇺🇸
Emory University Hospital, Atlanta, Georgia, United States

Beta Blockers and Angiotensin Receptor Blockers in Bicuspid Aortic Valve Disease Aortopathy (BAV Study)

Phase 3

Terminated

Conditions: Cardiac Disease

Interventions: Drug: Telmisartan
Drug: Atenolol

First Posted Date: 2010-09-16

Last Posted Date: 2019-09-18

Lead Sponsor: Hamilton Health Sciences Corporation

Target Recruit Count: 85

Registration Number: NCT01202721

Locations: 🇨🇦
Hamilton Health Sciences-General, Hamilton, Ontario, Canada
🇨🇦
St. Michael's Hospital, Toronto, Ontario, Canada
🇨🇦
Cité de la Santé de Laval, Laval, Quebec, Canada

and more 10 locations

Atenolol Versus Losartan in the Prevention of Progressive Dilation of the Aorta in Marfan Syndrome

Phase 3

Conditions: Marfan Syndrome

Interventions: Drug: Losartan
Drug: Atenolol

First Posted Date: 2010-06-16

Last Posted Date: 2010-08-12

Lead Sponsor: Forteza, Albert, M.D.

Target Recruit Count: 140

Registration Number: NCT01145612

Locations: 🇪🇸
Hospital 12 de Octubre, Madrid, Spain
🇪🇸
Hospital Vall d'Hebron, Barcelona, Spain

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