Quetiapine
- Generic Name
- Quetiapine
- Brand Names
- Seroquel
- Drug Type
- Small Molecule
- Chemical Formula
- C21H25N3O2S
- CAS Number
- 111974-69-7
- Unique Ingredient Identifier
- BGL0JSY5SI
- Background
Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment. It is well-tolerated and a suitable option for some patients with high sensitivi...
- Indication
Quetiapine is used in the symptomatic treatment of schizophrenia. In addition, it may be used for the management of acute manic or mixed episodes in patients with bipolar I disorder, as a monotherapy or combined with other drugs. It may be used to manage depressive episodes in bipolar disorder. In addition to the above indications, quetiapine is used in comb...
- Associated Conditions
- Bipolar 1 Disorder, Depressive Episodes, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Mixed manic depressive episode, Post Traumatic Stress Disorder (PTSD), Psychosis, Schizophrenia, Acute Manic episode
- Associated Therapies
- -
Group Cognitive Behavioral Therapy (CBT I) Vs. Quetiapine for Residual Insomnia Impairing Recovery Among Elderly With Stable Major Affective Disorders
- Conditions
- Interventions
- First Posted Date
- 2007-04-19
- Last Posted Date
- 2013-04-23
- Lead Sponsor
- Michael E. DeBakey VA Medical Center
- Target Recruit Count
- 32
- Registration Number
- NCT00462618
- Locations
- 🇺🇸
Michael Debakey VAMC, Houston, Texas, United States
A Comparison Study of the Efficacy of Quetiapine and Haloperidol in Agitated Adults in Emergency Room
- Conditions
- Interventions
- First Posted Date
- 2007-04-06
- Last Posted Date
- 2019-07-26
- Lead Sponsor
- University of Southern California
- Target Recruit Count
- 72
- Registration Number
- NCT00457366
- Locations
- 🇺🇸
Los Angeles County Hospital, Los Angeles, California, United States
Quetiapine for Bipolar Disorder and Alcohol Dependence
- Conditions
- Interventions
- First Posted Date
- 2007-04-06
- Last Posted Date
- 2016-04-05
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Target Recruit Count
- 90
- Registration Number
- NCT00457197
- Locations
- 🇺🇸
Psychoneuroendocrine Research Program, Dallas, Texas, United States
Comparison of Antipsychotics for Metabolic Problems in Schizophrenia or Schizoaffective Disorder
- Conditions
- Interventions
- First Posted Date
- 2007-01-18
- Last Posted Date
- 2016-11-02
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 215
- Registration Number
- NCT00423878
- Locations
- 🇺🇸
Medical College of Georgia, Augusta, Georgia, United States
🇺🇸John C Corrigan Community Mental Health Center, Fall River, Massachusetts, United States
🇺🇸Emory University, Atlanta, Georgia, United States
Psychotherapy for Bipolar II Depression, Pilot Study, Phase II
- Conditions
- Interventions
- First Posted Date
- 2006-12-14
- Last Posted Date
- 2017-05-30
- Lead Sponsor
- University of Pittsburgh
- Target Recruit Count
- 25
- Registration Number
- NCT00411463
- Locations
- 🇺🇸
University of Pittsburgh /University of Pittsburgh Medical Center (UPMC), Pittsburgh, Pennsylvania, United States
The Use of Quetiapine (Seroquel) in the Treatment of Social Phobia: Public Speaking Environment
- Conditions
- First Posted Date
- 2006-12-04
- Last Posted Date
- 2011-10-27
- Lead Sponsor
- University of Minnesota
- Target Recruit Count
- 20
- Registration Number
- NCT00407199
- Locations
- 🇺🇸
University of Minnesota, Minneapolis, Minnesota, United States
Naturalistic Study, Comparison of Divalproex Extended Release (ER) and Quetiapine for Adults With Acute Mania or Mixed Episodes
- First Posted Date
- 2006-11-08
- Last Posted Date
- 2019-09-11
- Lead Sponsor
- University of California, San Diego
- Target Recruit Count
- 30
- Registration Number
- NCT00397020
- Locations
- 🇺🇸
UCSD Medical Center, San Diego, California, United States
Compare the Effects of Bifeprunox and Quetiapine on Weight Changes in Stable Schizophrenic Patients
- First Posted Date
- 2006-11-06
- Last Posted Date
- 2008-06-04
- Lead Sponsor
- Solvay Pharmaceuticals
- Target Recruit Count
- 83
- Registration Number
- NCT00396214
- Locations
- 🇺🇸
Site 311, Santa Ana, California, United States
🇺🇸Site 330, Atlanta, Georgia, United States
🇺🇸Site 370, Decatur, Georgia, United States
Efficacy and Safety Study of Seroquel SR in the Treatment of Major Depressive Disorder
- Conditions
- First Posted Date
- 2006-10-17
- Last Posted Date
- 2010-04-01
- Lead Sponsor
- AstraZeneca
- Target Recruit Count
- 338
- Registration Number
- NCT00388973
- Locations
- 🇺🇦
Research Site, Vinnitsa, Ukraine
Safety and Efficacy of Divalproex and Quetiapine in Elderly Alzheimer's Dementia Patients
- Conditions
- Interventions
- First Posted Date
- 2006-09-13
- Last Posted Date
- 2015-05-27
- Lead Sponsor
- University of Cincinnati
- Registration Number
- NCT00375557
- Locations
- 🇺🇸
Cincinnati VA Hospital, Cincinnati, Ohio, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.