Quetiapine

Generic Name
Quetiapine
Brand Names
Seroquel
Drug Type
Small Molecule
Chemical Formula
C21H25N3O2S
CAS Number
111974-69-7
Unique Ingredient Identifier
BGL0JSY5SI
Background

Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment. It is well-tolerated and a suitable option for some patients with high sensitivi...

Indication

Quetiapine is used in the symptomatic treatment of schizophrenia. In addition, it may be used for the management of acute manic or mixed episodes in patients with bipolar I disorder, as a monotherapy or combined with other drugs. It may be used to manage depressive episodes in bipolar disorder. In addition to the above indications, quetiapine is used in comb...

Associated Conditions
Bipolar 1 Disorder, Depressive Episodes, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Mixed manic depressive episode, Post Traumatic Stress Disorder (PTSD), Psychosis, Schizophrenia, Acute Manic episode
Associated Therapies
-

Functional and Neurochemical Brain Changes in First-episode Bipolar Mania

Completed
Conditions
Interventions
First Posted Date
2008-02-06
Last Posted Date
2015-12-07
Lead Sponsor
University of Cincinnati
Target Recruit Count
81
Registration Number
NCT00609193
Locations
🇺🇸

University of Cincinnati, Cincinnati, Ohio, United States

A Double Blind, Placebo Controlled Trial of Quetiapine in Anorexia Nervosa, a Dual Site Study

Phase 2
Terminated
Conditions
First Posted Date
2008-01-02
Last Posted Date
2012-06-18
Lead Sponsor
University of South Florida
Target Recruit Count
24
Registration Number
NCT00584688
Locations
🇺🇸

University of South Floirda, Tampa, Florida, United States

Methamphetamine-Quetiapine Interactions in Humans

Early Phase 1
Terminated
Conditions
Interventions
First Posted Date
2007-12-05
Last Posted Date
2010-07-13
Lead Sponsor
University of Arkansas
Target Recruit Count
10
Registration Number
NCT00567866
Locations
🇺🇸

University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

Quetiapine Augmentation Versus Clomipramine Augmentation of SSRI for Obsessive-compulsive Disorder Patients

First Posted Date
2007-11-28
Last Posted Date
2017-10-27
Lead Sponsor
University of Sao Paulo
Target Recruit Count
21
Registration Number
NCT00564564
Locations
🇧🇷

Institute of Psychiatry, Clinics Hospital, University of São Paulo Medical School, São Paulo, SP, Brazil

Quetiapine Induced Neuroplasticity in First-episode Schizophrenic Patients

Phase 4
Completed
Conditions
Interventions
First Posted Date
2007-11-07
Last Posted Date
2011-10-24
Lead Sponsor
University of Regensburg
Target Recruit Count
30
Registration Number
NCT00554658
Locations
🇩🇪

University of Regensburg, Department of Psychiatry, Regensburg, Germany

Quetiapine and Concerta in the Treatment for ADHD and Aggressive Behavior.

First Posted Date
2007-10-29
Last Posted Date
2015-05-13
Lead Sponsor
Indiana University School of Medicine
Target Recruit Count
30
Registration Number
NCT00550147
Locations
🇺🇸

Riley Childrens Hospital, Indianapolis, Indiana, United States

Schizophrenia Sensory Gating Deficit With Quetiapine

Completed
Conditions
First Posted Date
2007-09-28
Last Posted Date
2007-12-31
Lead Sponsor
New Mexico VA Healthcare System
Target Recruit Count
20
Registration Number
NCT00536783
Locations
🇺🇸

New Mexico VA Healthcare System, Albuquerque, New Mexico, United States

Trial of Quetiapine in Anorexia Nervosa

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2007-08-21
Last Posted Date
2019-07-17
Lead Sponsor
University of California, San Diego
Target Recruit Count
21
Registration Number
NCT00518973
Locations
🇺🇸

UCSD Department of Psychiatry Center for Eating Disorder Research, San Diego, California, United States

Glucose and Lipid Metabolism on Antipsychotic Medication

First Posted Date
2007-08-14
Last Posted Date
2019-10-02
Lead Sponsor
Washington University School of Medicine
Target Recruit Count
96
Registration Number
NCT00515723
Locations
🇺🇸

Washington Univeristy School of Medicine, Saint Louis, Missouri, United States

🇺🇸

Washington University School of Medicine, Psychiatry Dept., Saint Louis, Missouri, United States

FAST-A Study to Evaluate the Efficacy and Safety of Quetiapin IR in Patients With Acute Psychosis

First Posted Date
2007-06-15
Last Posted Date
2010-12-10
Lead Sponsor
AstraZeneca
Registration Number
NCT00486798
Locations
🇸🇪

Research Site, Vaxjo, Sweden

© Copyright 2024. All Rights Reserved by MedPath