Quetiapine

Generic Name
Quetiapine
Brand Names
Seroquel
Drug Type
Small Molecule
Chemical Formula
C21H25N3O2S
CAS Number
111974-69-7
Unique Ingredient Identifier
BGL0JSY5SI
Background

Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment. It is well-tolerated and a suitable option for some patients with high sensitivi...

Indication

Quetiapine is used in the symptomatic treatment of schizophrenia. In addition, it may be used for the management of acute manic or mixed episodes in patients with bipolar I disorder, as a monotherapy or combined with other drugs. It may be used to manage depressive episodes in bipolar disorder. In addition to the above indications, quetiapine is used in comb...

Associated Conditions
Bipolar 1 Disorder, Depressive Episodes, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Mixed manic depressive episode, Post Traumatic Stress Disorder (PTSD), Psychosis, Schizophrenia, Acute Manic episode
Associated Therapies
-
Clinical Trials
Related News

Trazodone vs. Quetiapine for the Treatment of ICU Delirium

First Posted Date
2022-04-01
Last Posted Date
2024-05-08
Lead Sponsor
University of Southern California
Target Recruit Count
60
Registration Number
NCT05307003
Locations
🇺🇸

Keck Hospital of the University of Southern California, Los Angeles, California, United States

Sleep Disorders in Chronic Kidney Disease Patients

Phase 1
Not yet recruiting
Conditions
Chronic Kidney Diseases
Interventions
Drug: Quetiapine
First Posted Date
2022-02-15
Last Posted Date
2022-02-15
Lead Sponsor
Assiut University
Target Recruit Count
60
Registration Number
NCT05240261

Seroquel ® in Patients With Bipolar Disorder in Remission With Signs of Impaired Impulse Control

Not Applicable
Conditions
Bipolar Affective Disorder
Interventions
Drug: Quetiapine
First Posted Date
2021-10-28
Last Posted Date
2021-10-28
Lead Sponsor
Federal Stare Budgetary Scientific Institution, Mental Health Research Center
Target Recruit Count
30
Registration Number
NCT05098353
Locations
🇷🇺

Mental health research center, Moscow, Russian Federation

RCT: Trazodone vs Quetiapine vs Placebo for Treating ICU Delirium (TraQ)

First Posted Date
2021-10-20
Last Posted Date
2024-05-08
Lead Sponsor
University of Southern California
Target Recruit Count
30
Registration Number
NCT05085808
Locations
🇺🇸

Keck Hospital of the University of Southern California, Los Angeles, California, United States

The Safety, Tolerability, and Effectiveness of Quetiapine in Postpartum Depression

Phase 1
Recruiting
Conditions
Postpartum Depression
Interventions
Drug: Quetiapine
First Posted Date
2021-07-06
Last Posted Date
2022-03-21
Lead Sponsor
Verinder Sharma
Target Recruit Count
30
Registration Number
NCT04950868
Locations
🇨🇦

Parkwood Institute, London, Ontario, Canada

Comparison of Antidepressant Augmentation With Amantadine vs Pramipexole vs Quetiapine in Treatment Resistant Depression

First Posted Date
2021-06-23
Last Posted Date
2023-08-22
Lead Sponsor
All India Institute of Medical Sciences, Bhubaneswar
Target Recruit Count
150
Registration Number
NCT04936126
Locations
🇮🇳

All India Institute of Medical Sciences, Bhubaneswar, Orissa, India

Improving Sleep After TKA Using Mirtazapine and Quetiapine

Not Applicable
Not yet recruiting
Conditions
Osteo Arthritis Knee
Insomnia
Interventions
Drug: Placebo
Drug: Mirtazapine
Drug: Quetiapine
First Posted Date
2021-01-28
Last Posted Date
2023-06-02
Lead Sponsor
St. Anna Ziekenhuis, Geldrop, Netherlands
Target Recruit Count
165
Registration Number
NCT04728581
Locations
🇳🇱

St. Anna hospital, Geldrop, Netherlands

🇳🇱

Knowledge Center for Orthopedic Surgery, St. Anna hospital, Geldrop, Netherlands

A Study to Test the Effect of Different Doses of BI 1358894 and Quetiapine in People With Depression

First Posted Date
2020-08-20
Last Posted Date
2024-03-19
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
389
Registration Number
NCT04521478
Locations
🇺🇸

Atlanta Center, Atlanta, Georgia, United States

🇺🇸

Lehigh Center for Clinical Research, Allentown, Pennsylvania, United States

🇨🇦

Braxia Scientific Corp. (CRTCE Mississauga), Mississauga, Ontario, Canada

and more 117 locations

Valproate Alone or in Combination With Quetiapine for Severe COVID-19 Pneumonia With Agitated Delirium

First Posted Date
2020-08-14
Last Posted Date
2023-03-31
Lead Sponsor
University of Miami
Registration Number
NCT04513314

Atypical Antipsychotics Influence on the Safety of the Heart and Monitoring Indicators Model Building

First Posted Date
2020-06-24
Last Posted Date
2020-08-26
Lead Sponsor
Shanghai Mental Health Center
Target Recruit Count
350
Registration Number
NCT04446234
Locations
🇨🇳

CHINA, Shanghai, Minhang, China

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