Quetiapine

Generic Name
Quetiapine
Brand Names
Seroquel
Drug Type
Small Molecule
Chemical Formula
C21H25N3O2S
CAS Number
111974-69-7
Unique Ingredient Identifier
BGL0JSY5SI
Background

Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment. It is well-tolerated and a suitable option for some patients with high sensitivi...

Indication

Quetiapine is used in the symptomatic treatment of schizophrenia. In addition, it may be used for the management of acute manic or mixed episodes in patients with bipolar I disorder, as a monotherapy or combined with other drugs. It may be used to manage depressive episodes in bipolar disorder. In addition to the above indications, quetiapine is used in comb...

Associated Conditions
Bipolar 1 Disorder, Depressive Episodes, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Mixed manic depressive episode, Post Traumatic Stress Disorder (PTSD), Psychosis, Schizophrenia, Acute Manic episode
Associated Therapies
-

Effect of Quetiapine on Brain Activity Patterns in Patients With Heightened Risk of Bipolar Disorder

Not Applicable
Conditions
Interventions
First Posted Date
2015-05-21
Last Posted Date
2015-05-21
Lead Sponsor
RWTH Aachen University
Target Recruit Count
54
Registration Number
NCT02451306
Locations
🇩🇪

Clinic for psychiatry, psychotherapy and psychosomatic, RWTH Aachen University Hospital, Aachen, NRW, Germany

Pharmacovigilance in Gerontopsychiatric Patients

Phase 3
Terminated
Conditions
Interventions
Drug: Phenobarbital
Drug: Phenytoin
Drug: Carbamazepine
Drug: Oxcarbazepine
Drug: Valproic Acid
Drug: Lamotrigine
Drug: Topiramate
Drug: Gabapentin
Drug: Levetiracetam
Drug: Pregabalin
Drug: Lacosamide
Drug: Clonazepam
Drug: Biperiden
Drug: Levomepromazine
Drug: Fluphenazine
Drug: Perphenazine
Drug: Perazine
Drug: Thioridazine
Drug: Haloperidol
Drug: Melperone
Drug: Pipamperone
Drug: Bromperidol
Drug: Benperidol
Drug: Sertindole
Drug: Ziprasidone
Drug: Flupentixol
Drug: Chlorprothixene
Drug: Zuclopenthixol
Drug: Fluspirilene
Drug: Pimozide
Drug: Clozapine
Drug: Olanzapine
Drug: Quetiapine
Drug: Sulpiride
Drug: Tiapride
Drug: Amisulpride
Drug: Prothipendyl
Drug: Risperidone
Drug: Aripiprazole
Drug: Paliperidone
Drug: Diazepam
Drug: Oxazepam
Drug: Lorazepam
Drug: Bromazepam
Drug: Clobazam
Drug: Alprazolam
Drug: Hydroxyzine
Drug: Buspirone
Drug: Chloral Hydrate
Drug: Flurazepam
Drug: Nitrazepam
Drug: Triazolam
Drug: Lormetazepam
Drug: Temazepam
Drug: Midazolam
Drug: Brotizolam
Drug: Zopiclone
Drug: Zolpidem
Drug: Zaleplon
Drug: Melatonin
Drug: Clomethiazole
Drug: Diphenhydramine
Drug: Promethazine
Drug: Imipramine
Drug: Clomipramine
Drug: Opipramol
Drug: Trimipramine
Drug: Amitriptyline
Drug: Nortriptyline
Drug: Doxepin
Drug: Maprotiline
Drug: Amitriptyline oxide
Drug: Fluoxetine
Drug: Citalopram
Drug: Paroxetine
Drug: Sertraline
Drug: Fluvoxamine
Drug: Escitalopram
Drug: Tranylcypromine
Drug: Moclobemide
Drug: Mianserin
Drug: Trazodone
Drug: Mirtazapine
Drug: Bupropion
Drug: Venlafaxine
Drug: Reboxetine
Drug: Duloxetine
Drug: Agomelatine
Drug: Pyritinol
Drug: Piracetam
Drug: Donepezil
Drug: Rivastigmine
Drug: Galantamine
Drug: Memantine
Drug: Nicergoline
Drug: Acamprosate
Drug: Lithium
First Posted Date
2015-03-02
Last Posted Date
2018-02-28
Lead Sponsor
Hannover Medical School
Target Recruit Count
407
Registration Number
NCT02374567
Locations
🇩🇪

Bezirkskrankenhaus Augsburg, Augsburg, Germany

🇩🇪

Krankenhaus Hedwigshöhe, Berlin, Germany

🇩🇪

Hannover Medical School, Hannover, Germany

and more 2 locations

Comparative Study of Aripiprazole, Quetiapine and Ziprasidone in the Treatment of First Episode Nonaffective Psychosis

First Posted Date
2014-12-03
Last Posted Date
2017-03-14
Lead Sponsor
Fundación Marques de Valdecilla
Target Recruit Count
203
Registration Number
NCT02305823
Locations
🇪🇸

University Hospital Marques de Valdecilla, Santander, Cantabria, Spain

Prophylactic Quetiapine on Delirium Prevention in Critically Ill Patients

Phase 3
Conditions
Interventions
First Posted Date
2014-11-21
Last Posted Date
2014-11-21
Lead Sponsor
Seoul National University Hospital
Target Recruit Count
194
Registration Number
NCT02297763

A Randomized Double-blind Trial With 6 Antipsychotic Drugs for Schizophrenia

First Posted Date
2014-07-17
Last Posted Date
2016-07-12
Lead Sponsor
Beijing HuiLongGuan Hospital
Target Recruit Count
550
Registration Number
NCT02192723
Locations
🇨🇳

Beijing HuiLongGuan Hospital, Beijing, China

Antipsychotic to Treat Psychosis Syndrome

First Posted Date
2014-05-14
Last Posted Date
2014-05-14
Lead Sponsor
Central South University
Target Recruit Count
300
Registration Number
NCT02137616
Locations
🇨🇳

the Second Xiangya Hospital, Changsha, Hunan, China

Efficacy of Quetiapine for Pediatric Delirium

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2014-02-05
Last Posted Date
2017-12-13
Lead Sponsor
Weill Medical College of Cornell University
Target Recruit Count
6
Registration Number
NCT02056171
Locations
🇺🇸

Columbia University Medical Center, New York, New York, United States

🇺🇸

NY Prebyterian Hospital/Weill Cornell Medical Center, New York, New York, United States

Cannabidiol as a Different Type of an Antipsychotic: Drug Delivery and Interaction Study

First Posted Date
2014-01-31
Last Posted Date
2018-03-08
Lead Sponsor
Central Institute of Mental Health, Mannheim
Target Recruit Count
74
Registration Number
NCT02051387
Locations
🇩🇪

Dept. of Pharmacology, University of Cologne, Cologne, NRW, Germany

🇩🇪

Central Institute of Mental Health, Mannheim, BW, Germany

© Copyright 2024. All Rights Reserved by MedPath