Quetiapine
- Generic Name
- Quetiapine
- Brand Names
- Seroquel
- Drug Type
- Small Molecule
- Chemical Formula
- C21H25N3O2S
- CAS Number
- 111974-69-7
- Unique Ingredient Identifier
- BGL0JSY5SI
- Background
Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment. It is well-tolerated and a suitable option for some patients with high sensitivi...
- Indication
Quetiapine is used in the symptomatic treatment of schizophrenia. In addition, it may be used for the management of acute manic or mixed episodes in patients with bipolar I disorder, as a monotherapy or combined with other drugs. It may be used to manage depressive episodes in bipolar disorder. In addition to the above indications, quetiapine is used in comb...
- Associated Conditions
- Bipolar 1 Disorder, Depressive Episodes, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Mixed manic depressive episode, Post Traumatic Stress Disorder (PTSD), Psychosis, Schizophrenia, Acute Manic episode
- Associated Therapies
- -
Algorithm Guided Treatment Strategies for Bipolar Depression
- Conditions
- Interventions
- First Posted Date
- 2013-09-10
- Last Posted Date
- 2017-10-05
- Lead Sponsor
- Shanghai Mental Health Center
- Target Recruit Count
- 360
- Registration Number
- NCT01938859
- Locations
- 🇨🇳
Shanghai Mental Health Center, Shanghai, Shanghai, China
Comparative Efficacy and Acceptability of Antimanic Drugs in Acute Mania
- Conditions
- Interventions
- First Posted Date
- 2013-07-08
- Last Posted Date
- 2015-03-17
- Lead Sponsor
- Guiyun Xu
- Target Recruit Count
- 120
- Registration Number
- NCT01893229
- Locations
- 🇨🇳
Guangzhou Psychiatric Hospital, Guangzhou, Guangdong, China
Clinical Trial to Investigate the Effect on Corrected QT Interval Prolongation by Psychotropic Drugs
- Conditions
- Interventions
- First Posted Date
- 2013-06-07
- Last Posted Date
- 2014-06-03
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 40
- Registration Number
- NCT01871701
- Locations
- 🇰🇷
Seoul National University Bundang Hospital, Seongnam, Gyounggi, Korea, Republic of
Trial Comparing Haloperidol, Quetiapine and Placebo in the Pharmacological Treatment of Delirium
- First Posted Date
- 2013-03-14
- Last Posted Date
- 2018-02-09
- Target Recruit Count
- 107
- Registration Number
- NCT01811459
- Locations
- 🇨🇦
Centre hospitalier de l'Université de Montréal (CHUM), Montreal, Quebec, Canada
Quetiapine Pharmacotherapy for Cannabis Dependence
- First Posted Date
- 2012-10-02
- Last Posted Date
- 2019-03-05
- Lead Sponsor
- New York State Psychiatric Institute
- Target Recruit Count
- 130
- Registration Number
- NCT01697709
- Locations
- 🇺🇸
New York State Psychiatric Institute, New York, New York, United States
Comparison of Quetiapine and Trazodone Treatment for Insomnia in Dually Diagnosed Veterans
- Conditions
- Interventions
- First Posted Date
- 2012-08-10
- Last Posted Date
- 2018-10-16
- Lead Sponsor
- VA Connecticut Healthcare System
- Target Recruit Count
- 1
- Registration Number
- NCT01662297
- Locations
- 🇺🇸
VA Connecticut Healthcare System, West Haven, Connecticut, United States
A Study to Compare Capillary and Venous Whole Blood and Plasma Concentrations of Five Antipsychotics
- Conditions
- Interventions
- First Posted Date
- 2012-05-30
- Last Posted Date
- 2013-04-09
- Lead Sponsor
- Janssen Research & Development, LLC
- Target Recruit Count
- 31
- Registration Number
- NCT01607762
Sequential Multiple Assignment Treatment for Bipolar Disorder
- Conditions
- Interventions
- First Posted Date
- 2012-05-01
- Last Posted Date
- 2020-08-19
- Target Recruit Count
- 112
- Registration Number
- NCT01588457
- Locations
- 🇺🇸
Case Western Reserve University, Cleveland, Ohio, United States
🇺🇸University of Texas Health Science Center, San Antonio, Texas, United States
Effects of Quetiapine on Ultrastructural Hippocampal and Neurochemical Changes in Patients With Bipolar Disorder: Searching for Antidepressant and Mood Stabilising Neurophysiology
- First Posted Date
- 2012-03-13
- Last Posted Date
- 2012-03-13
- Lead Sponsor
- RWTH Aachen University
- Target Recruit Count
- 33
- Registration Number
- NCT01552837
- Locations
- 🇩🇪
Department of Psychiatry, Psychotherapy and Psychosomatics, University Hospital Aachen, Aachen, Germany
Gao Bipolar Spectrum Lithium/Quetiapine Study
- First Posted Date
- 2012-02-03
- Last Posted Date
- 2017-08-16
- Lead Sponsor
- University Hospitals Cleveland Medical Center
- Target Recruit Count
- 42
- Registration Number
- NCT01526148
- Locations
- 🇺🇸
University Hospitals Cleveland Medical Center - Mood Disorders Program, Cleveland, Ohio, United States
Drug Development Updates
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