Methylene blue
- Generic Name
- Methylene blue
- Brand Names
- Hyophen, Phosphasal, Provayblue, Proveblue, Urelle, Uribel, Urimar Reformulated Oct 2013, Urin DS, Urogesic Blue Reformulated Apr 2012, Ustell, Utira, Lumeblue (previously known as Methylthioninium chloride Cosmo), Methylthioninium chloride Proveblue
- Drug Type
- Small Molecule
- Chemical Formula
- C16H18ClN3S
- CAS Number
- 61-73-4
- Unique Ingredient Identifier
- 8NAP7826UB
- Background
Methylene blue is an oxidation-reduction agent. The intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult patients with acquired methemoglobinemia. Historically, it has been widely used in Africa to treat malaria, but now it disappeared when chloroquine (CQ) and other drugs entered the market. Its use as an urinar...
- Indication
Indicated for the treatment of pediatric and adult patients with acquired methemoglobinemia.
...
- Associated Conditions
- Cystitis, Methemoglobinemia, Nephritis, Urethritis, Urinary tract inflammation
- Associated Therapies
- Diuresis
Methylene Blue and Postoperative Neurocognitive Disorders
- Conditions
- Interventions
- First Posted Date
- 2020-08-27
- Last Posted Date
- 2024-02-13
- Lead Sponsor
- Fudan University
- Target Recruit Count
- 314
- Registration Number
- NCT04529265
- Locations
- 🇨🇳
Shanghai Cancer Center, Fudan University, Shanghai, China
Methylene Blue in Early Septic Shock
- First Posted Date
- 2020-06-25
- Last Posted Date
- 2022-11-04
- Lead Sponsor
- Hospital Civil de Guadalajara
- Target Recruit Count
- 91
- Registration Number
- NCT04446871
- Locations
- 🇲🇽
Hospital Civil Fray Antonio Alcalde, Guadalajara, Mexico
Intraoperative Infusion of Methylene Blue for Prevention of Postoperative Delirium and Cognitive Dysfunction in Elderly Patients Undergoing Major Elective Noncardiac Surgery
- Conditions
- Interventions
- First Posted Date
- 2020-04-10
- Last Posted Date
- 2020-10-27
- Lead Sponsor
- Fudan University
- Target Recruit Count
- 248
- Registration Number
- NCT04341844
- Locations
- 🇨🇳
Huashan Hospital, Shanghai, Shanghai, China
Methylene Blue and Microcirculation in Septic Shock
- First Posted Date
- 2020-03-05
- Last Posted Date
- 2020-03-05
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 32
- Registration Number
- NCT04295993
- Locations
- 🇪🇬
Cairo University, Cairo, Egypt
Clinical and Microbiologic Outcomes of aPDT in the Non-surgical Treatment of Implant Inflammation
- Conditions
- Interventions
- First Posted Date
- 2019-12-05
- Last Posted Date
- 2024-02-21
- Target Recruit Count
- 56
- Registration Number
- NCT04187053
- Locations
- 🇺🇸
University of Texas Health Science Center at Houston School of Dentistry, Houston, Texas, United States
Methylene Blue Versus Vasopressin Analogue for Treatment of Septic Shock in Preterm Neonate
- First Posted Date
- 2019-10-01
- Last Posted Date
- 2019-10-01
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 36
- Registration Number
- NCT04110418
- Locations
- 🇪🇬
Neonatal Intensive Care Units (NICUs), Ain Shams University, Cairo, Abbasia, Egypt
Effect of Methylene Blue on Perioperative Organ Function in Patients With Obstructive Jaundice
- First Posted Date
- 2019-09-30
- Last Posted Date
- 2019-10-01
- Lead Sponsor
- Jiaolin Ning,MD
- Target Recruit Count
- 64
- Registration Number
- NCT04109859
- Locations
- 🇨🇳
department of anesthesia, Southwest Hospital, Third Military Medical University Affiliation: Southwest Hospital, China, ChongQing, Chongqing, China
Methylene Blue as a Third-line Vasopressor in Septic Shock
- First Posted Date
- 2019-09-13
- Last Posted Date
- 2022-07-26
- Lead Sponsor
- Carilion Clinic
- Target Recruit Count
- 250
- Registration Number
- NCT04089072
- Locations
- 🇺🇸
Carilion Clinic, Roanoke, Virginia, United States
3D Printing for Nodule Localization
- Conditions
- Interventions
- First Posted Date
- 2019-08-14
- Last Posted Date
- 2019-08-14
- Lead Sponsor
- Wen-zhao ZHONG
- Target Recruit Count
- 47
- Registration Number
- NCT04056923
- Locations
- 🇨🇳
Guangdong Provincial People's Hospital, Guangzhou, Guangdong, China
Methylene Blue vs Cyanokit for Intraoperative Vasoplegic Syndrome in Liver Transplant Patients
- Conditions
- Interventions
- First Posted Date
- 2019-08-13
- Last Posted Date
- 2024-06-24
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 19
- Registration Number
- NCT04054999
- Locations
- 🇺🇸
Mayo Clinic in Florida, Jacksonville, Florida, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.