Amikacin
- Generic Name
- Amikacin
- Brand Names
- Arikayce, Arikayce liposomal
- Drug Type
- Small Molecule
- Chemical Formula
- C22H43N5O13
- CAS Number
- 37517-28-5
- Unique Ingredient Identifier
- 84319SGC3C
- Background
Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A. Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A.
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- Indication
The amikacin sulfate injection is indicated in the short-term treatment of serious bacterial infections due to susceptible strains of gram-negative bacteria, including Pseudomonas species, Escherichia coli, species of indole-positive and indole-negative Proteus, Providencia species, Klebsiella-Enterobacter-Serratia species, as well as Acinetobacter (Mima-Her...
- Associated Conditions
- Bacterial Peritonitis, Bone and Joint Infections, Burns, Central Nervous System Infections, Endophthalmitis, Infection caused by staphylococci, Infective pulmonary exacerbation of cystic fibrosis, Intraabdominal Infections, Meningitis, Bacterial, Mycobacterium avium complex infection, Neonatal Sepsis, Nosocomial Pneumonia, Postoperative Infections, Pulmonary Infections, Respiratory Tract Infection Bacterial, Sepsis Bacterial, Skin and Subcutaneous Tissue Bacterial Infections, Tuberculosis (TB), Grade 1, grade 2, grade 3, grade 4 Urinary Tract Infection, Severe Bacterial Infections
- Associated Therapies
- -
Fixed-dose Amikacin for Elderly UTI
- First Posted Date
- 2019-12-13
- Last Posted Date
- 2019-12-13
- Lead Sponsor
- Rabin Medical Center
- Target Recruit Count
- 200
- Registration Number
- NCT04197739
Optimized Antibiotic Therapy in Patients With Subarachnoid Haemorrhage (ES) and Cerebral Haemorrhage (EC)
- First Posted Date
- 2019-10-18
- Last Posted Date
- 2021-07-21
- Target Recruit Count
- 104
- Registration Number
- NCT04132115
- Locations
- 🇮🇹
Anesthesiology and Intensive Care Clinic - Department of Medicine - ASUIUD, Udine, Italy
🇮🇹Terapia Intensiva 1, Udine, Italy
DDI Study to Investigate Interaction Between Amikacin and POL7080
- First Posted Date
- 2016-09-13
- Last Posted Date
- 2017-02-01
- Lead Sponsor
- Polyphor Ltd.
- Target Recruit Count
- 14
- Registration Number
- NCT02897869
Effect of Additional Nebulized Amikacin in Ventilator-Associated Pneumonia Caused by Gram Negative Bacteria
- Conditions
- Interventions
- First Posted Date
- 2015-10-12
- Last Posted Date
- 2018-04-26
- Lead Sponsor
- Thammasat University
- Target Recruit Count
- 60
- Registration Number
- NCT02574130
- Locations
- 🇹🇭
Thammasat University (Rangsit center), Pathumthani, Thailand
Antibiotic Nephrotoxicity in Adult Patients With Cystic Fibrosis
- First Posted Date
- 2015-07-03
- Last Posted Date
- 2015-07-03
- Lead Sponsor
- The Leeds Teaching Hospitals NHS Trust
- Registration Number
- NCT02489955
- Locations
- 🇬🇧
Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
Pharmacokinetic/Pharmacodynamic Evaluation Amikacin in Critically Ill Patients Admitted at the Emergency Department
- First Posted Date
- 2015-02-18
- Last Posted Date
- 2015-02-18
- Lead Sponsor
- Universitaire Ziekenhuizen KU Leuven
- Target Recruit Count
- 100
- Registration Number
- NCT02365272
Combined Administration of Nebulized Amikacin in Patients With Acute Exacerbation of Non-Cystic Fibrosis Bronchiectasis
- Conditions
- Interventions
- First Posted Date
- 2014-03-07
- Last Posted Date
- 2019-04-24
- Lead Sponsor
- Qilu Hospital of Shandong University
- Target Recruit Count
- 178
- Registration Number
- NCT02081963
- Locations
- 🇨🇳
Qilu Hospital of Shandong University, Jinan, Shandong, China
Neonatal Suspected Sepsis Treated With Cefazolin or Vancomycin
- Conditions
- Interventions
- First Posted Date
- 2013-06-03
- Last Posted Date
- 2013-06-03
- Lead Sponsor
- Hospital Italiano de Buenos Aires
- Target Recruit Count
- 109
- Registration Number
- NCT01867138
- Locations
- 🇦🇷
Hospital Italiano de Buenos Aires, Buenos Aires, Capital, Argentina
Antibiotic Prophylaxis for Transrectal Prostate Biopsy
- Conditions
- Interventions
- First Posted Date
- 2012-08-08
- Last Posted Date
- 2019-06-25
- Lead Sponsor
- Northwestern University
- Target Recruit Count
- 563
- Registration Number
- NCT01659866
- Locations
- 🇺🇸
Northwestern University Department of Urology, Chicago, Illinois, United States
Inhaled Amikacin Treatment for Nontuberculous Mycobacterial Lung Disease
- Conditions
- Interventions
- First Posted Date
- 2012-02-08
- Last Posted Date
- 2012-12-17
- Lead Sponsor
- Samsung Medical Center
- Registration Number
- NCT01528930
- Locations
- 🇰🇷
Samsung Medical Center, Seoul, Korea, Republic of
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.