MedPath

Piperacillin

Generic Name
Piperacillin
Brand Names
Pipracil, Zosyn
Drug Type
Small Molecule
Chemical Formula
C23H27N5O7S
CAS Number
66258-76-2
Unique Ingredient Identifier
9I628532GX
Background

Semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. It is also used in combination with other antibiotics.

Indication

For the treatment of polymicrobial infections.

Associated Conditions
Animal bite, Bacterial Infections, Bone and Joint Infections, Community Acquired Pneumonia (CAP), Gynecological Infection, Infection, Mixed, Intraabdominal Infections, Lower Respiratory Tract Infection (LRTI), Nosocomial Pneumonia, Pelvic Infections, Septicemia, Skin and skin structure infections, Urinary Tract Infection, Uncomplicated Urethritis gonococcal caused by Neisseria Gonorrhoeae

Antimicrobial Prophylaxis in Thyroid and Parathyroid Surgery

Not Applicable
Completed
Conditions
Thyroid Disease
Parathyroid Disease
Interventions
First Posted Date
2013-03-06
Last Posted Date
2013-03-06
Lead Sponsor
Ito Hospital
Target Recruit Count
2164
Registration Number
NCT01805856
Locations
🇯🇵

Ito Hospital, Tokyo, Japan

Piperacillin Sodium and Sulbactam Sodium for Injection(2:1) for Treatment of Respiratory and Urinary System Infection

Phase 4
Completed
Conditions
Respiratory Tract Infections
Urinary Tract Infections
Interventions
First Posted Date
2013-01-03
Last Posted Date
2019-07-08
Lead Sponsor
Xiangbei Welman Pharmaceutical Co., Ltd
Target Recruit Count
2000
Registration Number
NCT01760109
Locations
🇨🇳

Chongqing Red Cross hospital, Chongqing, China

Prophylactic Piperacillin/Tazobactam in Hematopoietic Stem Cell Transplantation

Not Applicable
Conditions
Neutropenia
Hematopoietic Stem Cell Transplantation
Interventions
First Posted Date
2012-10-26
Last Posted Date
2012-10-26
Lead Sponsor
Chinese PLA General Hospital
Target Recruit Count
150
Registration Number
NCT01714557
Locations
🇨🇳

Chinese PLA general hospital, Beijing, Beijing, China

Initial Antibiotics and Delayed Appendectomy for Acute Appendicitis

Not Applicable
Completed
Conditions
Acute Appendicitis
Interventions
First Posted Date
2012-10-02
Last Posted Date
2015-05-06
Lead Sponsor
Rhode Island Hospital
Target Recruit Count
73
Registration Number
NCT01697059
Locations
🇺🇸

Hasbro Children's Hospital (Rhode Island Hospital), Providence, Rhode Island, United States

A Study Comparing Continuous Infusion Antibiotics to Standard Treatment for Lung Infections in Cystic Fibrosis

First Posted Date
2012-08-17
Last Posted Date
2017-04-20
Lead Sponsor
The Alfred
Target Recruit Count
50
Registration Number
NCT01667094
Locations
🇦🇺

The Alfred Hospital, Melbourne, Victoria, Australia

Assessment of the Optimal Dosing of Piperacillin-tazobactam in Intensive Care Unit Patients: Extended Versus Continuous Infusion

Phase 4
Completed
Conditions
Infectious Disease
Interventions
First Posted Date
2010-09-10
Last Posted Date
2018-05-11
Lead Sponsor
University Hospital, Ghent
Target Recruit Count
14
Registration Number
NCT01198925
Locations
🇧🇪

University Hospital Ghent, Ghent, Belgium

Study Evaluating BLI-489 and Piperacillin in Healthy Subjects

Phase 1
Completed
Conditions
Healthy Subjects
Interventions
Drug: BLI-489/Piperacillin
First Posted Date
2009-05-07
Last Posted Date
2009-07-17
Lead Sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Target Recruit Count
24
Registration Number
NCT00894439

Ertapenem Sodium vs. Piperacillin/Tazobactam in the Treatment of Complicated Intra-Abdominal Infections (0826-037)

Phase 3
Completed
Conditions
Complicated Intra-Abdominal Infections
First Posted Date
2006-10-19
Last Posted Date
2017-02-17
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
300
Registration Number
NCT00389987

Prevention of Infection in Patients With Hematologic Cancer and Persistent Fever Caused by a Low White Blood Cell Count

Phase 3
Completed
Conditions
Bone Marrow Suppression
Fever, Sweats, and Hot Flashes
Infection
Leukemia
Lymphoma
Multiple Myeloma and Plasma Cell Neoplasm
Myelodysplastic Syndromes
Unspecified Adult Solid Tumor, Protocol Specific
Unspecified Childhood Solid Tumor, Protocol Specific
First Posted Date
2004-07-16
Last Posted Date
2012-09-24
Lead Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Target Recruit Count
859
Registration Number
NCT00003805
Locations
🇧🇪

Algemeen Ziekenhuis Middelheim, Antwerp, Belgium

🇨🇭

Universitaetsspital, Zurich, Switzerland

🇨🇭

Ospedale San Giovanni, Bellinzona, Switzerland

and more 25 locations
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