Ivermectin

Generic Name
Ivermectin
Brand Names
Sklice, Soolantra, Stromectol
Drug Type
Small Molecule
Chemical Formula
C95H146O28
CAS Number
70288-86-7
Unique Ingredient Identifier
8883YP2R6D
Background

Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A (22,23-dihydroavermectin B) and 10%...

Indication

Administered topically, ivermectin cream is indicated for the treatment of inflammatory lesions associated with rosacea. An over-the-counter ivermection lotion is commercially available and indicated for the topical treatment of head lice infestations in patients ≥6 months of age.
...

Associated Conditions
Ascariasis, Demodex Infestation, Enterobiasis, Filariasis caused by Loa Loa, Gnathostomiasis, Head Lice Infestation, Malaria, Myiasis, Onchocerciasis caused by Infection with Onchocerca volvulus, Rosacea, Scabies, Strongyloidiasis caused by Strongyloides Stercoralis Infection, Trichuriasis
Associated Therapies
-
Clinical Trials
Related News

Ivermectin Treatment of Persons With Onchocerciasis-associated Epilepsy

Phase 4
Completed
Conditions
Epilepsy
Interventions
Drug: ivermectin
First Posted Date
2019-02-25
Last Posted Date
2019-09-26
Lead Sponsor
Universiteit Antwerpen
Target Recruit Count
197
Registration Number
NCT03852303
Locations
🇨🇩

Centre de Recherche en Maladies Tropicales de l'Ituri, Rethy, Ituri, Congo, The Democratic Republic of the

Effect of Ivermectin Metabolites on Mosquito Survival

Phase 4
Completed
Conditions
Healthy
Interventions
Drug: Ivermectin
First Posted Date
2018-10-01
Last Posted Date
2024-11-26
Lead Sponsor
University of Oxford
Target Recruit Count
20
Registration Number
NCT03690453
Locations
🇹🇭

Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

PK PD Study of IDA and Azithromycin for NTDs ( ComboNTDs )

First Posted Date
2018-09-10
Last Posted Date
2019-02-28
Lead Sponsor
Lihir Medical Centre
Target Recruit Count
42
Registration Number
NCT03664063
Locations
🇵🇬

Lihir Medical Centre, Londolovit, New Ireland Province, Papua New Guinea

Treatment of Strongyloides Infection

First Posted Date
2018-07-30
Last Posted Date
2023-11-30
Lead Sponsor
Albert Einstein College of Medicine
Target Recruit Count
51
Registration Number
NCT03605758
Locations
🇺🇸

Jacobi Medical Center, Bronx, New York, United States

Ivermectin and Human Immunity

Early Phase 1
Completed
Conditions
Ivermectin
Interventions
Other: Placebo
Drug: Ivermectin
First Posted Date
2018-03-09
Last Posted Date
2019-07-12
Lead Sponsor
University of Georgia
Target Recruit Count
12
Registration Number
NCT03459794
Locations
🇺🇸

University of Georgia, Athens, Georgia, United States

Pharmacokinetics and Pharmacodynamics of Ivermectin in Pediatric Dengue Patients

Phase 2
Completed
Conditions
Dengue Hemorrhagic Fever
Interventions
Drug: Ivermectin
First Posted Date
2018-02-14
Last Posted Date
2021-02-24
Lead Sponsor
Mahidol University
Target Recruit Count
24
Registration Number
NCT03432442
Locations
🇹🇭

Faculty of Tropical Medicine Siriraj Hospital, Bangkok Noi, Bangkok, Thailand

IVM Alone vs ALB + IVM Against Onchocerciasis

Phase 3
Completed
Conditions
Onchocerciasis
Interventions
Drug: Ivermectin
Drug: Albendazole
First Posted Date
2017-08-03
Last Posted Date
2017-08-29
Lead Sponsor
University Hospitals Cleveland Medical Center
Target Recruit Count
272
Registration Number
NCT03238131
Locations
🇬🇭

Committee on Human Research Publications and Ethics, Kumasi, Ashanti, Ghana

Impact of Community Scabies Treatment on Head Lice Prevalence in the Solomon Islands

First Posted Date
2017-08-01
Last Posted Date
2019-06-14
Lead Sponsor
London School of Hygiene and Tropical Medicine
Target Recruit Count
118
Registration Number
NCT03236168
Locations
🇸🇧

Atoifi Adventist Hospital, Atoifi, Malaita, Solomon Islands

Insecticide Resistance Management in Burkina Faso and Côte D'Ivoire

First Posted Date
2017-03-08
Last Posted Date
2024-10-01
Lead Sponsor
Institut de Recherche pour le Developpement
Target Recruit Count
15776
Registration Number
NCT03074435
Locations
🇧🇫

Institut de Recherche en Sciences de la Santé, Bobo-Dioulasso, Burkina Faso

🇨🇮

Institut Pierre Richet, Bouaké, Côte D'Ivoire

Ivermectin Treatment in Patients With Onchocerciasis-associated Epilepsy

Phase 4
Completed
Conditions
Ivermectin
Onchocerciasis
Epilepsy
Interventions
Drug: Ivermectin
First Posted Date
2017-02-14
Last Posted Date
2019-01-07
Lead Sponsor
Robert Colebunders
Target Recruit Count
91
Registration Number
NCT03052998
Locations
🇨🇩

Centre de Recherche en Maladies Tropicales de l'Ituri, Rethy, Ituri, Congo, The Democratic Republic of the

© Copyright 2024. All Rights Reserved by MedPath
HomeTerms & ConditionsPrivacy Policy