Clarithromycin

Generic Name: Clarithromycin

Brand Names: Biaxin, Biaxin Bid, Omeclamox, Prevpac, Voquezna 14 Day Triplepak 20;500;500

Drug Type: Small Molecule

Chemical Formula: C_₃₈H_₆₉NO_₁₃

CAS Number: 81103-11-9

Unique Ingredient Identifier: H1250JIK0A

Background: Clarithromycin, a semisynthetic macrolide antibiotic derived from erythromycin, inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the translation and protein assembly process. Clarithromycin may be bacteriostatic or bacteri...

Indication: An alternative medication for the treatment of acute otitis media caused by H. influenzae, M. catarrhalis, or S. pneumoniae in patients with a history of type I penicillin hypersensitivity. Also for the treatment of pharyngitis and tonsillitis caused by susceptible Streptococcus pyogenes, as well as respiratory tract infections including acute maxillary sinu...

Associated Conditions: Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB), Acute maxillary sinusitis, Bacterial Infections, Bartonellosis, Community Acquired Pneumonia (CAP), Duodenal ulcer caused by helicobacter pylori, Helicobacter Pylori Infection, Infective Endocarditis (IE), Lyme Disease, Mycobacterial Infections, Otitis Media (OM), Pertussis, Streptococcal Pharyngitis, Tonsillitis streptococcal, Uncomplicated skin and subcutaneous tissue bacterial infections

Associated Therapies: -

Clinical Trials

The PK and PD Interaction Between YH4808, Amoxicillin and Clarithromycin in Healthy Subjects

Phase 1

Completed

Conditions: Healthy

Interventions: Drug: YH4808
Drug: Nexium
Drug: Amoxicillin
Drug: clarithromycin

First Posted Date: 2013-08-13

Last Posted Date: 2013-12-03

Lead Sponsor: Yuhan Corporation

Target Recruit Count: 95

Registration Number: NCT01921647

Locations: 🇰🇷
Yonsei University Severance Hospital, Seoul, Korea, Republic of

15-day Sequential Therapy for Helicobacter Pylori Infection in Korea

Phase 4

Completed

Conditions: Helicobacter Pylori Infection

Interventions: Drug: Clarithromycin
Drug: metronidazole
Drug: esomeprazole

First Posted Date: 2013-06-26

Last Posted Date: 2013-08-13

Lead Sponsor: Seoul National University Bundang Hospital

Target Recruit Count: 287

Registration Number: NCT01887249

Locations: 🇰🇷
Seoul National University Bundang Hospital, Bundang-gu, Seongnam, Gyeonggi-do, Korea, Republic of

Pharmacokinetic Study of Clarithromycin in Very Low Birth Weight (VLBW)

Phase 2

Terminated

Conditions: Very Low Birth Weight Infant
Ureaplasma/Mycoplasma Positive

Interventions: Drug: Clarithromycin

First Posted Date: 2013-05-13

Last Posted Date: 2014-11-19

Lead Sponsor: Seoul National University Hospital

Target Recruit Count: 6

Registration Number: NCT01851954

Locations: 🇰🇷
Seoul National University Children's Hospital, Seoul, Korea, Republic of

The Effect of Gemfibrozil, Ketoconazole and Clarithromycin on the Amount of LY2409021 in the Bloodstream

Phase 1

Completed

Conditions: Healthy Volunteers

Interventions: Drug: LY2409021
Drug: Gemfibrozil
Drug: Ketoconazole
Drug: Clarithromycin

First Posted Date: 2013-04-19

Last Posted Date: 2019-03-08

Lead Sponsor: Eli Lilly and Company

Target Recruit Count: 30

Registration Number: NCT01836198

Locations: 🇺🇸
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Evansville, Indiana, United States

Autologous Stem Cell Transplant With Pomalidomide (CC-4047®) Maintenance Versus Continuous Clarithromycin/ Pomalidomide / Dexamethasone Salvage Therapy in Relapsed or Refractory Multiple Myeloma

Phase 2

Active, not recruiting

Conditions: Multiple Myeloma

Interventions: Drug: Pomalidomide
Procedure: stem cell
Drug: Dexamethasone
Drug: Clarithromycin

First Posted Date: 2012-12-10

Last Posted Date: 2024-07-03

Lead Sponsor: Memorial Sloan Kettering Cancer Center

Target Recruit Count: 23

Registration Number: NCT01745588

Locations: 🇺🇸
Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, United States
🇺🇸
North Shore LIJ, New Hyde Park, New York, United States
🇺🇸
Memorial Sloan Kettering Cancer Center @ Suffolk, Commack, New York, United States

and more 6 locations