MedPath

Alcaftadine

Generic Name
Alcaftadine
Brand Names
Lastacaft
Drug Type
Small Molecule
Chemical Formula
C19H21N3O
CAS Number
147084-10-4
Unique Ingredient Identifier
7Z8O94ECSX
Background

Alcaftadine is a H1 histamine receptor antagonist indicated for the prevention of itching associated with allergic conjunctivitis. This drug was approved in July 2010.

Indication

用于2岁以上人群过敏性结膜炎相关性眼部瘙痒的治疗。

Associated Conditions
Allergic Conjunctivitis (AC)

Safety and Efficacy of Lastacaft® for the Prevention of Itching Associated With Allergic Conjunctivitis in Korea

Completed
Conditions
Conjunctivitis, Allergic
Interventions
First Posted Date
2015-09-22
Last Posted Date
2019-07-05
Lead Sponsor
Allergan
Target Recruit Count
3423
Registration Number
NCT02555761
Locations
🇰🇷

Ian Eye Center, Seoul, Korea, Republic of

🇰🇷

Soonchunhyang University Cheonan Hospital, Chungcheongnam-do, Korea, Republic of

🇰🇷

St. Mary's Eye center, Geyonggi-do, Korea, Republic of

and more 73 locations

A Single-Center Evaluation of the Anti-Inflammatory Effects of Lastacaft as Measured by In-Vivo Confocal Microscopy

Phase 4
Completed
Conditions
Allergic Conjunctivitis
Interventions
Drug: Tears Naturale ® (Placebo)
First Posted Date
2014-12-04
Last Posted Date
2021-03-18
Lead Sponsor
ORA, Inc.
Target Recruit Count
25
Registration Number
NCT02308501

AGN-229666 Ophthalmic Solution in Japanese Patients With Allergic Conjunctivitis

Phase 3
Completed
Conditions
Conjunctivitis, Allergic
Interventions
Drug: Vehicle to AGN-229666
First Posted Date
2014-06-11
Last Posted Date
2019-04-17
Lead Sponsor
Allergan
Target Recruit Count
240
Registration Number
NCT02161146

AGN-229666 Ophthalmic Solution for the Treatment of Seasonal or Perennial Allergic Conjunctivitis

Phase 3
Completed
Conditions
Conjunctivitis, Allergic
Interventions
First Posted Date
2014-03-10
Last Posted Date
2016-03-14
Lead Sponsor
Allergan
Target Recruit Count
140
Registration Number
NCT02082262

Ocular Allergy Treatment Practical Impact Trial

Phase 4
Conditions
Allergic Conjunctivitis
Rhinoconjunctivitis
Interventions
First Posted Date
2013-03-11
Last Posted Date
2013-05-30
Lead Sponsor
Starx Research Center, LLC
Target Recruit Count
50
Registration Number
NCT01808768
Locations
🇺🇸

STARx, Springfield, New Jersey, United States

🇺🇸

STARx Research Center, Edison, New Jersey, United States

AGN-229666 for the Treatment of Allergic Conjunctivitis

Phase 2
Completed
Conditions
Allergic Conjunctivitis
Interventions
Other: vehicle of AGN-229666
First Posted Date
2012-12-21
Last Posted Date
2014-02-04
Lead Sponsor
Allergan
Target Recruit Count
90
Registration Number
NCT01754766

A Study to Evaluate the Efficacy of Lastacaft® Compared to Pataday™ and Placebo in Patients With Acute Allergic Conjunctivitis

First Posted Date
2012-11-26
Last Posted Date
2014-01-14
Lead Sponsor
Allergan
Target Recruit Count
157
Registration Number
NCT01732757

A Study to Evaluate the Duration of LASTACAFT® in Acute Allergic Conjunctivitis

First Posted Date
2011-11-11
Last Posted Date
2013-02-21
Lead Sponsor
Allergan
Target Recruit Count
127
Registration Number
NCT01470118

Safety and Efficacy Study of a Eye Drop for Eye Allergy

Phase 3
Completed
Conditions
Allergic Conjunctivitis
Interventions
Drug: Placebo
First Posted Date
2009-04-28
Last Posted Date
2015-03-06
Lead Sponsor
Vistakon Pharmaceuticals
Target Recruit Count
60
Registration Number
NCT00889330
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