Ipratropium
- Generic Name
- Ipratropium
- Brand Names
- Atrovent, Combivent, Ipravent
- Drug Type
- Small Molecule
- Chemical Formula
- C20H30NO3
- CAS Number
- 60205-81-4
- Unique Ingredient Identifier
- GR88G0I6UL
- Background
Ipratropium is a quaternary ammonium derivative of atropine that acts as an anticholinergic agent. It is commonly administered through inhalation which allows producing a local effect without presenting a significant systemic absorption.
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- Indication
Inhaled ipratropium is indicated in combination with inhaled beta-agonist systemic corticosteroids for the management of severe exacerbations of asthma flares requiring treatment.
Asthma exacerbations are characterized by a progressive increase in one or more of asthma symptoms accompanied by a decrease in expiratory flow.
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- Associated Conditions
- Acute Exacerbation of Asthma, Asthma, Bronchospasm, Chronic Obstructive Pulmonary Disease (COPD), Nasal Congestion Associated With the Common Cold, Non-Allergic Rhinitis, Perennial Allergic Rhinitis (PAR), Rhinitis
- Associated Therapies
- -
Effectiveness of Ipratropium Bromide in Preventing Exercise-induced Bronchoconstriction in Athletes
- Conditions
- Interventions
- First Posted Date
- 2012-09-24
- Last Posted Date
- 2020-06-05
- Lead Sponsor
- University of California, San Francisco
- Target Recruit Count
- 20
- Registration Number
- NCT01691079
- Locations
- 🇺🇸
University of California, San Francisco, San Francisco, California, United States
A Study to Look at Day to Day Changes in Lung Function in COPD Subjects Taking Albuterol/Salbutamol and Ipratropium
- Conditions
- Interventions
- First Posted Date
- 2012-09-24
- Last Posted Date
- 2018-06-20
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 56
- Registration Number
- NCT01691482
- Locations
- 🇬🇧
GSK Investigational Site, Manchester, United Kingdom
Magnesium Sulfate Versus Ipratropuim Bromide in Acute Exacerbation of Chronic Obstructive Pulmonary Disease
- Conditions
- Interventions
- First Posted Date
- 2010-06-03
- Last Posted Date
- 2010-06-03
- Lead Sponsor
- University of Monastir
- Target Recruit Count
- 124
- Registration Number
- NCT01136421
- Locations
- 🇹🇳
University Hospital of Monastir, Monastir, Monstir, Tunisia
🇹🇳Soudani Marghli, Mahdia, Tunisia
Study to Assess the Effect of Salbutamol and Ipratropium Bromide in Chronic Obstructive Pulmonary Disease (COPD) Patients
- First Posted Date
- 2009-06-02
- Last Posted Date
- 2009-06-02
- Lead Sponsor
- University Hospital, Antwerp
- Target Recruit Count
- 6
- Registration Number
- NCT00911651
- Locations
- 🇧🇪
Antwerp University Hospital, Antwerp, Belgium
Sensitivity of New Exercise Tests in Chronic Obstructive Pulmonary Disease (COPD)
- Conditions
- Interventions
- First Posted Date
- 2008-12-12
- Last Posted Date
- 2011-02-09
- Lead Sponsor
- Laval University
- Target Recruit Count
- 44
- Registration Number
- NCT00807534
- Locations
- 🇨🇦
François Maltais, Quebec City, Quebec, Canada
🇨🇦Hélène Perrault, Montreal, Quebec, Canada
Duration of Protective Effect From Inhaled Ipratropium Bromide on Methacholine Airway Hyperresponsiveness
- First Posted Date
- 2008-01-31
- Last Posted Date
- 2009-01-07
- Lead Sponsor
- University of Saskatchewan
- Target Recruit Count
- 12
- Registration Number
- NCT00605410
- Locations
- 🇨🇦
University of Saskatchewan, Saskatoon, Saskatchewan, Canada
Study of Budesonide as an Addition to Standard Therapy in Adult Asthmatics in the Emergency Room.
- Conditions
- Interventions
- First Posted Date
- 2008-01-08
- Last Posted Date
- 2016-01-21
- Lead Sponsor
- Northwell Health
- Target Recruit Count
- 95
- Registration Number
- NCT00588406
- Locations
- 🇺🇸
Nassau University Medical Center, East Meadow, New York, United States
🇺🇸Long Island Jewish Medical Center, Queens, New York, United States
🇺🇸Jacobi Medical Center, Bronx, New York, United States
A Comparison of Levalbuterol Plus Ipratropium With Levalbuterol Alone in the Treatment of Acute Asthma Exacerbation
- First Posted Date
- 2007-12-31
- Last Posted Date
- 2022-05-16
- Lead Sponsor
- MetroHealth Medical Center
- Target Recruit Count
- 141
- Registration Number
- NCT00583778
- Locations
- 🇺🇸
MetroHealth Medical Center, Cleveland, Ohio, United States
Optimising the Propranolol Block Model
- Conditions
- Interventions
- First Posted Date
- 2007-10-25
- Last Posted Date
- 2017-08-04
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 18
- Registration Number
- NCT00549120
- Locations
- 🇬🇧
GSK Investigational Site, London, United Kingdom
Prevention of Lung Edema After Thoracic Surgery
- Conditions
- First Posted Date
- 2007-07-10
- Last Posted Date
- 2007-07-10
- Lead Sponsor
- University Hospital, Geneva
- Target Recruit Count
- 30
- Registration Number
- NCT00498251
- Locations
- 🇨🇭
University Hospital of Geneva, Geneva, Switzerland
Drug Development Updates
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