Fluorescein
- Generic Name
- Fluorescein
- Brand Names
- Ak-fluor, Altafluor, Diofluor, Fluorescite, Fluress
- Drug Type
- Small Molecule
- Chemical Formula
- C20H12O5
- CAS Number
- 2321-07-5
- Unique Ingredient Identifier
- TPY09G7XIR
- Background
A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal injuries and corneal trauma. It has been approved by FDA for use in externally applied drugs and cosmetics. (From Merck Index, 12th ed; American Medical Associ...
- Indication
For diagnostic imaging. Primarily indicated in diagnostic fluorescein angiography or angioscopy of the fundus and of the iris vasculature.
- Associated Conditions
- Peritoneal dialysis therapy, Pneumocystis Jirovecii Pneumonia
- Associated Therapies
- -
Optical Tissue Identification for Myocardial Architecture
- Conditions
- Interventions
- First Posted Date
- 2019-07-12
- Last Posted Date
- 2023-06-15
- Lead Sponsor
- Aditya Kaza
- Target Recruit Count
- 70
- Registration Number
- NCT04017975
- Locations
- 🇺🇸
Boston Children's Hospital, Boston, Massachusetts, United States
Study of Performance of Confocal Endomicroscope With Fluorescein Imaging Agent in the Colon
- Conditions
- Interventions
- First Posted Date
- 2017-07-18
- Last Posted Date
- 2022-11-22
- Lead Sponsor
- University of Michigan
- Target Recruit Count
- 72
- Registration Number
- NCT03220711
- Locations
- 🇺🇸
University of Michigan, Ann Arbor, Michigan, United States
Utilization of Confocal Microscopy During Cardiac Surgery
- Conditions
- Interventions
- First Posted Date
- 2017-06-16
- Last Posted Date
- 2020-07-07
- Lead Sponsor
- Aditya Kaza
- Target Recruit Count
- 6
- Registration Number
- NCT03189134
- Locations
- 🇺🇸
Boston Children's Hospital, Boston, Massachusetts, United States
Evaluation of Fluorescein Use During Cystoscopy
- Conditions
- Interventions
- First Posted Date
- 2016-03-09
- Last Posted Date
- 2018-01-12
- Lead Sponsor
- Johns Hopkins University
- Registration Number
- NCT02703558
Diagnostic Performance of Fluorescein as an Intraoperative Brain Tumor Biomarker
- First Posted Date
- 2016-02-25
- Last Posted Date
- 2024-06-25
- Lead Sponsor
- David W. Roberts
- Target Recruit Count
- 30
- Registration Number
- NCT02691923
- Locations
- 🇺🇸
Sally B Mansur, Lebanon, New Hampshire, United States
Use of Fluorescein Dye for the Removal of Brain Tumors
- First Posted Date
- 2015-03-17
- Last Posted Date
- 2018-08-03
- Lead Sponsor
- University of Pittsburgh
- Target Recruit Count
- 91
- Registration Number
- NCT02389530
- Locations
- 🇺🇸
UPMC Shadyside Hospital, Pittsburgh, Pennsylvania, United States
Efficacy of Fluorescein Visualization of the Uterus in Detecting Endometrial Cancer Invasion
- First Posted Date
- 2013-11-08
- Last Posted Date
- 2022-02-24
- Lead Sponsor
- University of Arkansas
- Target Recruit Count
- 100
- Registration Number
- NCT01979003
- Locations
- 🇺🇸
University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States
Fluorescein for Sentinel Lymph Node Biopsy (SLNB) in Breast Cancer
- First Posted Date
- 2012-06-07
- Last Posted Date
- 2013-07-10
- Lead Sponsor
- University of Utah
- Registration Number
- NCT01614184
A Feasibility Study of Confocal Microendoscopy in the Evaluation of Gastrointestinal Neoplasia -Project 1
- Conditions
- Interventions
- First Posted Date
- 2011-06-29
- Last Posted Date
- 2016-01-12
- Lead Sponsor
- Anandasabapathy, Sharmila, M.D.
- Target Recruit Count
- 67
- Registration Number
- NCT01384695
- Locations
- 🇺🇸
Mount Sinai Medical Center, New York, New York, United States
Advanced Gastrointestinal Endoscopic Imaging
- First Posted Date
- 2009-12-17
- Last Posted Date
- 2024-06-26
- Lead Sponsor
- Stanford University
- Target Recruit Count
- 3
- Registration Number
- NCT01034670
- Locations
- 🇺🇸
Stanford University School of Medicine, Stanford, California, United States
Drug Development Updates
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