Stavudine

Generic Name
Stavudine
Brand Names
Zerit
Drug Type
Small Molecule
Chemical Formula
C10H12N2O4
CAS Number
3056-17-5
Unique Ingredient Identifier
BO9LE4QFZF
Background

A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.

Indication

For the treatment of human immunovirus (HIV) infections.

Associated Conditions
Human Immunodeficiency Virus (HIV) Infections
Associated Therapies
-

A Study of d4T in Patients With AIDS or AIDS-Related Complex Who Cannot Take AZT

Phase 1
Terminated
Conditions
First Posted Date
2001-08-31
Last Posted Date
2008-08-26
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
35
Registration Number
NCT00000686
Locations
🇺🇸

Cornell Univ Med Ctr, New York, New York, United States

A Study of BMY-27857 in Patients With AIDS or AIDS Related Complex

Phase 1
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2008-08-26
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
40
Registration Number
NCT00000988
Locations
🇺🇸

Mount Sinai Med Ctr, New York, New York, United States

🇺🇸

Cornell Univ Med Ctr, New York, New York, United States

The Safety and Effectiveness of Didanosine Plus Stavudine Plus Delavirdine Mesylate Plus MKC-442 in HIV-Infected Patients Who Have Not Had Success With Protease Inhibitors

Phase 2
Terminated
Conditions
First Posted Date
2001-08-31
Last Posted Date
2008-08-14
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
25
Registration Number
NCT00002420
Locations
🇺🇸

Pacific Oaks Med Group, Beverly Hills, California, United States

The Safety and Effectiveness of Didanosine Plus Stavudine Plus Nevirapine Combined With MKC-442 in HIV-Infected Patients Who Have Not Had Success With Protease Inhibitors

Phase 2
Terminated
Conditions
First Posted Date
2001-08-31
Last Posted Date
2008-08-14
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
25
Registration Number
NCT00002418
Locations
🇺🇸

Univ of Colorado / Health Science Ctr, Denver, Colorado, United States

🇺🇸

Brown Univ School of Medicine, Providence, Rhode Island, United States

🇺🇸

AIDS Research Consortium of Atlanta, Atlanta, Georgia, United States

and more 2 locations

A Study of Three Anti-HIV Drug Combinations in Patients Who Have Taken Amprenavir

Phase 2
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-11-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
94
Registration Number
NCT00001095
Locations
🇺🇸

St Louis Regional Hosp / St Louis Regional Med Ctr, Saint Louis, Missouri, United States

🇺🇸

Univ of North Carolina, Chapel Hill, North Carolina, United States

🇺🇸

Univ of Southern California / LA County USC Med Ctr, Los Angeles, California, United States

and more 9 locations

Safety and Effectiveness of Four Anti-HIV Drug Combinations in HIV-Infected Children and Teens

Phase 1
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-11-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
200
Registration Number
NCT00001091
Locations
🇺🇸

Harbor - UCLA Med Ctr / UCLA School of Medicine, Los Angeles, California, United States

🇺🇸

State Univ of New York at Stony Brook, Stony Brook, New York, United States

🇺🇸

Children's Hosp of Philadelphia, Philadelphia, Pennsylvania, United States

and more 52 locations

A Randomized, Comparative Trial of Zidovudine (AZT) Versus 2',3'-Didehydro-3'-Deoxythymidine (Stavudine; d4T) in Children With HIV Infection

Phase 2
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-11-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
230
Registration Number
NCT00000789
Locations
🇺🇸

Usc La Nichd Crs, Los Angeles, California, United States

🇺🇸

The Children's Hosp. of Philadelphia IMPAACT CRS, Philadelphia, Pennsylvania, United States

🇺🇸

St. Christopher's Hosp. for Children, Philadelphia, Pennsylvania, United States

and more 51 locations

A Study of Indinavir Sulfate Plus Zidovudine (AZT) Plus Lamivudine in HIV-Infected Patients Who Have Taken AZT for Six or More Months

Phase 3
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-11-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
1750
Registration Number
NCT00000841
Locations
🇺🇸

Univ of Southern California / LA County USC Med Ctr, Los Angeles, California, United States

🇺🇸

UCLA CARE Ctr, Los Angeles, California, United States

🇺🇸

Emory Univ, Atlanta, Georgia, United States

and more 84 locations

A Phase I/II Double-Blind Controlled Trial to Determine the Safety and Immunogenicity of HIV-1 MN rgp160 Immuno AG Vaccine Therapy in HIV-Infected Individuals With Greater Than or Equal to 500/mm3 CD4+ T Cells and 200-400/mm3 CD4+ T Cells

Phase 1
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-10-29
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
46
Registration Number
NCT00000822
Locations
🇺🇸

Stanford CRS, Stanford, California, United States

A Study on the Effect of Chemotherapy Combined With Anti-HIV Drugs in HIV-Positive Patients

Phase 1
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-10-29
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
10
Registration Number
NCT00000899
Locations
🇺🇸

Univ of North Carolina, Chapel Hill, North Carolina, United States

🇺🇸

Duke Univ Med Ctr, Durham, North Carolina, United States

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