Stavudine

Generic Name
Stavudine
Brand Names
Zerit
Drug Type
Small Molecule
Chemical Formula
C10H12N2O4
CAS Number
3056-17-5
Unique Ingredient Identifier
BO9LE4QFZF
Background

A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.

Indication

For the treatment of human immunovirus (HIV) infections.

Associated Conditions
Human Immunodeficiency Virus (HIV) Infections
Associated Therapies
-

Comparison of Stavudine Used Alone or in Combination With Didanosine in HIV-Infected Children

Phase 2
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-11-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
198
Registration Number
NCT00000851
Locations
🇺🇸

Univ. of Maryland Med. Ctr., Div. of Ped. Immunology & Rheumatology, Baltimore, Maryland, United States

🇺🇸

St. Christopher's Hosp. for Children, Philadelphia, Pennsylvania, United States

🇺🇸

Cook County Hosp., Chicago, Illinois, United States

and more 32 locations

Safety and Effectiveness of Giving Indinavir Plus Stavudine Plus Lamivudine to HIV-Infected Children

Phase 1
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-10-28
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
24
Registration Number
NCT00000901
Locations
🇺🇸

UCSD Med Ctr / Pediatrics / Clinical Sciences, La Jolla, California, United States

🇺🇸

Univ of Florida Health Science Ctr / Pediatrics, Jacksonville, Florida, United States

🇺🇸

Incarnation Children's Ctr / Columbia Presbyterian Med Ctr, New York, New York, United States

and more 16 locations

A Study of HIV-Disease Development in Aging

Phase 2
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-11-01
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
90
Registration Number
NCT00006144
Locations
🇺🇸

Santa Clara Valley Med. Ctr., San Jose, California, United States

🇺🇸

Mt. Sinai Med. Ctr. A0404 CRS, New York, New York, United States

🇺🇸

Columbia Univ., HIV Prevention and Treatment Medical Ctr., New York, New York, United States

and more 42 locations

Five-Drug Anti-HIV Treatment Followed by Treatment Interruption in Patients Who Have Recently Been Infected With HIV

Phase 2
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-10-29
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
121
Registration Number
NCT00000940
Locations
🇺🇸

SSTAR, Family Healthcare Ctr., Fall River, Massachusetts, United States

🇺🇸

Ucsf Aids Crs, San Francisco, California, United States

🇺🇸

USC CRS, Los Angeles, California, United States

and more 15 locations

The Effectiveness of Nelfinavir and Efavirenz, Used Alone or Together, Combined With Other Anti-HIV Drugs in Patients Who Have Taken Anti-HIV Drugs

Phase 2
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-11-01
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
300
Registration Number
NCT00001087
Locations
🇺🇸

Rush Univ. Med. Ctr. ACTG CRS, Chicago, Illinois, United States

🇺🇸

Cook County Hosp. CORE Ctr., Chicago, Illinois, United States

🇺🇸

Johns Hopkins Adult AIDS CRS, Baltimore, Maryland, United States

and more 3 locations

ABT-378/Ritonavir in Combination With Reverse Transcriptase Inhibitors in Antiretroviral Naïve HIV-Infected Subjects

First Posted Date
2001-08-31
Last Posted Date
2008-04-03
Lead Sponsor
Abbott
Target Recruit Count
100
Registration Number
NCT00004578
Locations
🇺🇸

Northwestern University Medical School, Chicago, Illinois, United States

🇺🇸

University of Colorado Health Sciences Center, Denver, Colorado, United States

🇺🇸

Baylor College of Medicine, Houston, Texas, United States

and more 7 locations

A Comparison of Epivir Plus Crixivan Combined With Zerit or Retrovir in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs

Not Applicable
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2007-10-02
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
200
Registration Number
NCT00002369
Locations
🇵🇷

San Juan AIDS Program, Santurce, Puerto Rico

🇺🇸

Boston Univ Med Ctr Hosp / Evans - 556, Boston, Massachusetts, United States

🇺🇸

HIV Clinical Research Ctr, Fort Lauderdale, Florida, United States

and more 8 locations

A Comparison of Two Anti-HIV Triple-Drug Combinations in HIV-Infected Patients

Not Applicable
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2007-10-02
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
200
Registration Number
NCT00002168
Locations
🇺🇸

Univ of Nebraska, Omaha, Nebraska, United States

🇺🇸

Anderson Clinical Research, Washington, District of Columbia, United States

🇵🇷

Hosp Regional de Ponce - Area Vieja, Ponce, Puerto Rico

and more 10 locations

A Study to Compare the Effectiveness of a Four Drug Anti-HIV Regimen Given Alone or in Combination With GM-CSF or IL-12 to HIV-Positive Patients

Not Applicable
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-10-29
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
24
Registration Number
NCT00000896
Locations
🇺🇸

Ucsd, Avrc Crs, San Diego, California, United States

🇺🇸

University of Colorado Hospital CRS, Aurora, Colorado, United States

🇺🇸

Indiana Univ. School of Medicine, Infectious Disease Research Clinic, Indianapolis, Indiana, United States

Effectiveness of Anti-HIV Therapy (HAART) in HIV-Infected Patients With Tuberculosis

Phase 1
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2008-09-11
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
44
Registration Number
NCT00004736
Locations
🇺🇸

Univ of California / San Diego Treatment Ctr, San Diego, California, United States

🇺🇸

Univ of Southern California / LA County USC Med Ctr, Los Angeles, California, United States

🇺🇸

Vanderbilt Univ Med Ctr, Nashville, Tennessee, United States

and more 7 locations
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