Stavudine

Generic Name
Stavudine
Brand Names
Zerit
Drug Type
Small Molecule
Chemical Formula
C10H12N2O4
CAS Number
3056-17-5
Unique Ingredient Identifier
BO9LE4QFZF
Background

A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.

Indication

For the treatment of human immunovirus (HIV) infections.

Associated Conditions
Human Immunodeficiency Virus (HIV) Infections
Associated Therapies
-

Virologic Responses To New Nucleoside Regimens After Prolonged ZDV or ddI Monotherapy

Phase 2
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-11-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
280
Registration Number
NCT00000831
Locations
🇺🇸

USC CRS, Los Angeles, California, United States

🇺🇸

Regional Center for Infectious Disease, Wendover Medical Center CRS, Greensboro, North Carolina, United States

🇺🇸

Beth Israel Deaconess - East Campus A0102 CRS, Boston, Massachusetts, United States

and more 37 locations

Antiviral Activity of and Resistance to Lamivudine in Combination With Zidovudine, Stavudine, or Didanosine

Phase 2
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-11-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
256
Registration Number
NCT00000838
Locations
🇺🇸

Stanford CRS, Palo Alto, California, United States

🇺🇸

Santa Clara Valley Med. Ctr., San Jose, California, United States

🇺🇸

San Mateo County AIDS Program, San Mateo, California, United States

and more 29 locations

A Study of Three Treatment Combinations Using Zidovudine Plus Lamivudine Plus Indinavir in HIV-Infected Patients

Phase 2
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-11-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
500
Registration Number
NCT00001084
Locations
🇺🇸

Univ of Southern California / LA County USC Med Ctr, Los Angeles, California, United States

🇺🇸

Santa Clara Valley Med Ctr / AIDS Community Rsch Consortium, San Jose, California, United States

🇺🇸

Stanford Univ Med Ctr, Stanford, California, United States

and more 42 locations

The Effectiveness of Three Drug Combinations in HIV-Infected Patients Who Have Taken Zidovudine for More Than 12 Weeks

Phase 2
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-11-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
200
Registration Number
NCT00001063
Locations
🇺🇸

Massachusetts General Hospital ACTG CRS, Boston, Massachusetts, United States

🇺🇸

Bmc Actg Crs, Boston, Massachusetts, United States

🇺🇸

Beth Israel Deaconess Med. Ctr., ACTG CRS, Boston, Massachusetts, United States

and more 30 locations

A Study to Compare Two Different Anti-HIV Drug Regimens

Phase 2
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-10-29
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
120
Registration Number
NCT00000924
Locations
🇺🇸

Harbor - UCLA Med Ctr / UCLA School of Medicine, Los Angeles, California, United States

🇺🇸

Cook County Hosp, Chicago, Illinois, United States

🇺🇸

Chicago Children's Memorial Hosp, Chicago, Illinois, United States

and more 42 locations

A Study of the Safety and Effectiveness of Hydroxyurea in Patients on Potent Antiretroviral Therapy and Who Have Less Than 200 Copies/ml of HIV RNA in Their Blood

Phase 2
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-10-29
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
399
Registration Number
NCT00000916
Locations
🇺🇸

Harbor-UCLA Med. Ctr. CRS, Torrance, California, United States

🇺🇸

Weiss Memorial Hosp., Chicago, Illinois, United States

🇺🇸

Massachusetts General Hospital ACTG CRS, Boston, Massachusetts, United States

and more 31 locations

Effectiveness of Anti-HIV Drugs in Patients Who Have Not Received Previous Anti-HIV Drugs During Different Stages of HIV Infection

Not Applicable
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2011-03-02
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
24
Registration Number
NCT00006443
Locations
🇺🇸

Michael S. Saag, Birmingham, Alabama, United States

A Study to Compare the Effectiveness of Different Anti-HIV Drug Regimens in Keeping Levels of HIV in the Blood as Low as Possible

Phase 2
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-10-29
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
150
Registration Number
NCT00000939
Locations
🇺🇸

Santa Clara Valley Med Ctr / AIDS Community Rsch Consortium, San Jose, California, United States

🇺🇸

San Mateo AIDS Program / Stanford Univ, Stanford, California, United States

🇺🇸

Bellevue Hosp / New York Univ Med Ctr, New York, New York, United States

and more 16 locations

The Effectiveness of Three Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Never Used Anti-HIV Drugs

Phase 2
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-11-01
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
105
Registration Number
NCT00001067
Locations
🇺🇸

Alabama Therapeutics CRS, Birmingham, Alabama, United States

🇺🇸

Ucsd, Avrc Crs, San Diego, California, United States

🇺🇸

Stanford CRS, Palo Alto, California, United States

and more 10 locations

Effects of Two Anti-HIV Drug Combinations on the Immune Systems of HIV-Infected Patients Who Have Never Received Anti-HIV Drugs

Not Applicable
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-11-01
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
55
Registration Number
NCT00004855
Locations
🇺🇸

Univ of Southern California / LA County USC Med Ctr, Los Angeles, California, United States

🇺🇸

Denver Dept of Health and Hosps, Denver, Colorado, United States

🇺🇸

Northwestern Univ Med School, Chicago, Illinois, United States

and more 20 locations
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