Stavudine

Generic Name
Stavudine
Brand Names
Zerit
Drug Type
Small Molecule
Chemical Formula
C10H12N2O4
CAS Number
3056-17-5
Unique Ingredient Identifier
BO9LE4QFZF
Background

A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.

Indication

For the treatment of human immunovirus (HIV) infections.

Associated Conditions
Human Immunodeficiency Virus (HIV) Infections
Associated Therapies
-

Strategies for Delivering Anti-HIV Therapy in South Africa

Not Applicable
Completed
Conditions
First Posted Date
2004-04-07
Last Posted Date
2007-09-18
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
813
Registration Number
NCT00080522
Locations
🇿🇦

University of the Witwatersrand/Clinical HIV Research Unit, Johannesburg, Gauteng, South Africa

🇿🇦

University of Cape Town/Masiphumelele, Cape Town, South Peninsula, South Africa

Preventing Sexual Transmission of HIV With Anti-HIV Drugs

First Posted Date
2003-12-17
Last Posted Date
2021-11-05
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
3526
Registration Number
NCT00074581
Locations
🇺🇸

Fenway Community Health Ctr. CRS, Boston, Massachusetts, United States

🇧🇼

Gaborone CRS, Gaborone, Botswana

🇧🇷

Hospital Geral de Nova Iguaçu CRS (HGNI CRS), Nova Iguacu, Rio De Janeiro, Brazil

and more 14 locations

When to Start Anti-HIV Drugs in Patients With Opportunistic Infections

First Posted Date
2003-02-20
Last Posted Date
2014-10-15
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
283
Registration Number
NCT00055120
Locations
🇺🇸

Brigham and Womens Hospital, Boston, Massachusetts, United States

🇺🇸

University of California, Davis Medical Center, Sacramento, California, United States

🇺🇸

Santa Clara Valley Medical Center, Stanford, California, United States

and more 42 locations

Comparing the Safety, Effectiveness, and Tolerability of Three Anti-HIV Drug Regimens for Treatment-Naive Patients

Phase 3
Completed
Conditions
First Posted Date
2003-01-01
Last Posted Date
2021-11-01
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
775
Registration Number
NCT00050895
Locations
🇺🇸

IHV Baltimore Treatment CRS, Baltimore, Maryland, United States

🇺🇸

UCLA CARE Center CRS, Los Angeles, California, United States

🇺🇸

Univ. of Miami AIDS CRS, Miami, Florida, United States

and more 57 locations

A Pilot Study of the Immunologic Reconstitution in HIV-1 Infected Children Receiving Highly Active Antiretroviral Therapy With Combination Ritonavir, Nevirapine and Stavudine

Phase 2
Completed
Conditions
First Posted Date
2002-05-22
Last Posted Date
2008-03-04
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
25
Registration Number
NCT00001688
Locations
🇺🇸

National Cancer Institute (NCI), Bethesda, Maryland, United States

A Study to Compare Anti-HIV Drugs Given Twice a Day or Once a Day, With or Without Direct Observation

Phase 2
Completed
Conditions
First Posted Date
2002-05-13
Last Posted Date
2021-11-01
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
402
Registration Number
NCT00036452
Locations
🇺🇸

The Ohio State Univ. AIDS CRS, Columbus, Ohio, United States

🇺🇸

MetroHealth CRS, Cleveland, Ohio, United States

🇺🇸

Pitt CRS, Pittsburgh, Pennsylvania, United States

and more 26 locations

Study of Anti-HIV Therapy Intensification

Not Applicable
Completed
Conditions
First Posted Date
2002-04-23
Last Posted Date
2012-05-18
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
22
Registration Number
NCT00034086
Locations
🇺🇸

Rush Univ. Med. Ctr. ACTG CRS, Chicago, Illinois, United States

🇺🇸

Case CRS, Cleveland, Ohio, United States

🇺🇸

University of Colorado Hospital CRS, Aurora, Colorado, United States

Treatment With Interleukin-2 (IL-2) Plus Combination Anti-HIV-Drug Therapy (HAART) for Patients Formerly in ACTG 328

Not Applicable
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2012-05-21
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
110
Registration Number
NCT00000923
Locations
🇺🇸

St. Louis ConnectCare, Infectious Diseases Clinic, St Louis, Missouri, United States

🇺🇸

Harbor-UCLA Med. Ctr. CRS, Torrance, California, United States

🇺🇸

Case CRS, Cleveland, Ohio, United States

and more 9 locations

Treatment Success and Failure in HIV-Infected Subjects Receiving Indinavir in Combination With Nucleoside Analogs: A Rollover Study for ACTG 320

Phase 2
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-10-28
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
440
Registration Number
NCT00000885
Locations
🇺🇸

Johns Hopkins Hosp, Baltimore, Maryland, United States

🇺🇸

Division of Inf Diseases/ Indiana Univ Hosp, Indianapolis, Indiana, United States

🇺🇸

Boston Med Ctr, Boston, Massachusetts, United States

and more 50 locations

Immunologic and Virologic Consequences of Long-Term Highly Active Antiretroviral Therapy (HAART) in Subjects With Moderately Advanced HIV-1 Disease: A Follow-Up Study to ACTG 315

Phase 2
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-11-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
34
Registration Number
NCT00000891
Locations
🇺🇸

Case Western Reserve Univ, Cleveland, Ohio, United States

🇺🇸

Univ of Colorado Health Sciences Ctr, Denver, Colorado, United States

🇺🇸

Rush Presbyterian - Saint Luke's Med Ctr, Chicago, Illinois, United States

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