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Nimesulide

Generic Name
Nimesulide
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C13H12N2O5S
CAS Number
51803-78-2
Unique Ingredient Identifier
V4TKW1454M
Background

Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. Due to concerns about the risk of hepatotoxicity, nimesulide has been withdrawn from market in many countries.

Indication

For the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old.

Associated Conditions
Acute Pain, Menstrual Distress (Dysmenorrhea), Pain
Associated Therapies
NSAIDs

Comparative Analysis of the Effectiveness of the Use of Nimesulide and CBD Oil in Patients With Pain in the Preauricular Region Due to the Pain-dysfunctional Syndrome of the Temporomandibular Joint.

Phase 2
Conditions
Temporomandibular Joint Disorders
Temporomandibular Joint Dysfunction Syndrome
Temporomandibular Joint Pain
Interventions
First Posted Date
2020-10-30
Last Posted Date
2021-01-29
Lead Sponsor
Pomeranian Medical University Szczecin
Target Recruit Count
30
Registration Number
NCT04609748
Locations
🇵🇱

Chair and Depratment of Dental Prosthetics, Szczecin, Poland

A Prevention Trial in Subjects at High Risk for Breast Cancer

Phase 2
Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2011-12-28
Last Posted Date
2014-06-18
Lead Sponsor
European Institute of Oncology
Target Recruit Count
150
Registration Number
NCT01500577
Locations
🇮🇹

European Institute of Oncology, Milan, Italy

Efficacy of Diclofenac Potassium vs Nimesulide in the Treatment of Fever and Pain in Children With Upper Respiratory Tract Infection

Phase 4
Withdrawn
Conditions
Upper Respiratory Tract Infections
Interventions
First Posted Date
2010-12-09
Last Posted Date
2012-04-26
Lead Sponsor
Novartis Pharmaceuticals
Registration Number
NCT01257126
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