Venlafaxine

Generic Name
Venlafaxine
Brand Names
Effexor
Drug Type
Small Molecule
Chemical Formula
C17H27NO2
CAS Number
93413-69-5
Unique Ingredient Identifier
GRZ5RCB1QG
Background

Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). Its active metabolite, desvenlafaxine, works by blocking the reuptake of serotonin and norepinephrine, which are key neurotransmitters in mood regulation. Venlafaxine is officially approved to treat major depressive disorder (MDD), generalized anxiety disorder (GAD...

Indication

Venlafaxine is indicated for the management of major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder (SAD), and panic disorder.

Associated Conditions
Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Migraine, Neuropathic Pain, Panic Disorder, Social Anxiety Disorder (SAD), Vasomotor Symptoms Associated With Menopause
Associated Therapies
-

Combination Treatment Study for Memory Impairment and Depression

First Posted Date
2012-08-06
Last Posted Date
2017-10-17
Lead Sponsor
New York State Psychiatric Institute
Target Recruit Count
86
Registration Number
NCT01658228
Locations
🇺🇸

New York State Psychiatric Institute, New York, New York, United States

🇺🇸

Duke University, Durham, North Carolina, United States

Venlafaxine in Preventing Chronic Oxaliplatin-Induced Neuropathy In Patients Receiving Combination Chemotherapy

First Posted Date
2012-06-04
Last Posted Date
2019-09-26
Lead Sponsor
Mayo Clinic
Target Recruit Count
50
Registration Number
NCT01611155
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

Venlafaxine for Depression in Alzheimer's Disease (DIADs-3)

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2012-06-01
Last Posted Date
2018-01-31
Lead Sponsor
Johns Hopkins University
Target Recruit Count
5
Registration Number
NCT01609348
Locations
🇺🇸

Johns Hopkins at Bayview, Baltimore, Maryland, United States

🇺🇸

Reading Hospital, West Reading, Pennsylvania, United States

The Treatment of Traumatised Refugees With Sertraline Versus Venlafaxine in Combination With Psychotherapy

First Posted Date
2012-04-03
Last Posted Date
2015-03-04
Lead Sponsor
Charlotte Sonne
Target Recruit Count
207
Registration Number
NCT01569685
Locations
🇩🇰

Competence Center for Transcultural Psychiatry, Gentofte, Denmark

Estimate the Efficiency of the Association of an Injection of Ketamine and the Venlafaxine in the Severe Major Depressive Disorder for Six Weeks

First Posted Date
2012-03-19
Last Posted Date
2017-02-24
Lead Sponsor
University Hospital, Grenoble
Target Recruit Count
25
Registration Number
NCT01557712
Locations
🇫🇷

Centre hospitalier universitaire, Grenoble, France

Quality of Life Study Using Gabapentin Versus Venlafaxine in Treating Hot Flashes in Patients With Prostate Cancer

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2012-02-15
Last Posted Date
2019-11-21
Lead Sponsor
University of Wisconsin, Madison
Target Recruit Count
5
Registration Number
NCT01533753
Locations
🇺🇸

University of Wisconsin Hospital and Clinics (Carbone Cancer Center), Madison, Wisconsin, United States

Bioavailability Study of Venlafaxine MR Capsules 150 mg Under Fed Conditions

Phase 1
Completed
Conditions
Interventions
First Posted Date
2012-01-19
Last Posted Date
2012-01-19
Lead Sponsor
Dr. Reddy's Laboratories Limited
Target Recruit Count
33
Registration Number
NCT01512459
Locations
🇮🇳

Bioserve Clinical Research (P) Ltd, Balanagar, Hyderabad, India

Effect of Duloxetine and Venlafaxine on the Pharmacokinetics and Pharmacodynamics of Oral Tramadol: A Three-phase Randomized Balanced Cross-over Study in Healthy Volunteers

Phase 4
Completed
Conditions
Interventions
First Posted Date
2011-09-29
Last Posted Date
2012-05-22
Lead Sponsor
Turku University Hospital
Target Recruit Count
12
Registration Number
NCT01443520
Locations
🇫🇮

Department of Anaesthesiology, Intensive Care, Emergency Care and Pain Medicine, Turku University and Turku University Hospital, Turku, Finland

Combination of Antidepressants and Fingolimod Relapsing-remitting Multiple Sclerosis (RRMS) Patients With Depression

First Posted Date
2011-09-20
Last Posted Date
2014-09-25
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
54
Registration Number
NCT01436643
Locations
🇩🇪

Novartis Investigative Site, Zwickau, Germany

Electroencephalography (EEG) Signal Processing

First Posted Date
2011-06-08
Last Posted Date
2011-11-30
Lead Sponsor
St. Joseph's Healthcare Hamilton
Target Recruit Count
150
Registration Number
NCT01369290
Locations
🇨🇦

St. Joseph's Healthcare, Centre for Mountain Health Services, Hamilton, Ontario, Canada

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