MedPath

Flutamide

Generic Name
Flutamide
Brand Names
Eulexin
Drug Type
Small Molecule
Chemical Formula
C11H11F3N2O3
CAS Number
13311-84-7
Unique Ingredient Identifier
76W6J0943E
Background

An antiandrogen with about the same potency as cyproterone in rodent and canine species.

Indication

For the management of locally confined Stage B2-C and Stage D2 metastatic carcinoma of the prostate

Associated Conditions
Stage B2-C metastatic Carcinoma of the Prostate, Stage D2 metastatic Carcinoma of the Prostate

Hormone Therapy Plus Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Prostate Cancer

Phase 3
Completed
Conditions
Prostate Cancer
Interventions
Drug: Luteinizing hormone releasing hormone [LHRH] agonist
Radiation: Radiation therapy
First Posted Date
2003-01-27
Last Posted Date
2020-10-22
Lead Sponsor
Radiation Therapy Oncology Group
Target Recruit Count
397
Registration Number
NCT00004054
Locations
🇺🇸

Lutheran General Cancer Care Center, Park Ridge, Illinois, United States

🇺🇸

Greater Baltimore Medical Center and Cancer Center, Baltimore, Maryland, United States

🇺🇸

Kimmel Cancer Center at Thomas Jefferson University - Philadelphia, Philadelphia, Pennsylvania, United States

and more 51 locations

Hormone Therapy in Treating Patients With Advanced Prostate Cancer

Phase 3
Completed
Conditions
Prostate Cancer
First Posted Date
2003-01-27
Last Posted Date
2012-07-02
Lead Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Target Recruit Count
966
Registration Number
NCT00003026
Locations
🇳🇱

St. Elisabeth Ziekenhuis, Tilburg, Netherlands

🇳🇱

Academisch Ziekenhuis Groningen, Groningen, Netherlands

🇬🇧

City General Hospital, Stoke-On-Trent, England, United Kingdom

and more 14 locations

Adjuvant Radiation Therapy Plus Hormone Therapy Compared With Radiation Therapy Alone in Treating Patients With Stage II or Stage III Prostate Cancer

Phase 3
Completed
Conditions
Prostate Cancer
Interventions
Procedure: adjuvant therapy
Radiation: radiation therapy
Drug: releasing hormone agonist therapy
First Posted Date
2003-01-27
Last Posted Date
2020-10-22
Lead Sponsor
Radiation Therapy Oncology Group
Target Recruit Count
67
Registration Number
NCT00023829
Locations
🇨🇦

Toronto Sunnybrook Regional Cancer Centre, Toronto, Ontario, Canada

S0032, Combination Chemotherapy Plus Hormone Therapy in Treating Patients With Metastatic Prostate Cancer

First Posted Date
2003-01-27
Last Posted Date
2013-07-16
Lead Sponsor
SWOG Cancer Research Network
Target Recruit Count
41
Registration Number
NCT00028769
Locations
🇺🇸

USC/Norris Comprehensive Cancer Center and Hospital, Los Angeles, California, United States

🇺🇸

CCOP - Atlanta Regional, Atlanta, Georgia, United States

🇺🇸

CCOP - Central Illinois, Decatur, Illinois, United States

and more 88 locations

Antineoplaston Therapy in Treating Patients With Stage III or Stage IV Prostate Cancer

Phase 2
Withdrawn
Conditions
Adenocarcinoma of the Prostate
Stage III Prostate Cancer
Stage IV Prostate Cancer
Recurrent Prostate Cancer
First Posted Date
2003-01-27
Last Posted Date
2013-07-10
Lead Sponsor
Burzynski Research Institute
Registration Number
NCT00003517
Locations
🇺🇸

Burzynski Clinic, Houston, Texas, United States

Three Drug Combination Therapy Versus Conventional Treatment of Children With Congenital Adrenal Hyperplasia

Phase 4
Completed
Conditions
Congenital Adrenal Hyperplasia (CAH)
Interventions
First Posted Date
1999-11-04
Last Posted Date
2024-05-10
Lead Sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Target Recruit Count
62
Registration Number
NCT00001521
Locations
🇺🇸

National Institutes of Health Clinical Center, Bethesda, Maryland, United States

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