Flutamide

Generic Name
Flutamide
Brand Names
Eulexin
Drug Type
Small Molecule
Chemical Formula
C11H11F3N2O3
CAS Number
13311-84-7
Unique Ingredient Identifier
76W6J0943E
Background

An antiandrogen with about the same potency as cyproterone in rodent and canine species.

Indication

For the management of locally confined Stage B2-C and Stage D2 metastatic carcinoma of the prostate

Associated Conditions
Stage B2-C metastatic Carcinoma of the Prostate, Stage D2 metastatic Carcinoma of the Prostate
Associated Therapies
-

Comparative Study of Alternative Antiandrogen (AA) Therapy and Early Initiating of Enzalutamide for Castration-resistant Prostate Cancer (CRPC) After Combined Androgen Blockade (CAB) Therapy.

First Posted Date
2015-01-27
Last Posted Date
2021-09-16
Lead Sponsor
Taro Iguchi, MD, PHD
Target Recruit Count
104
Registration Number
NCT02346578
Locations
🇯🇵

Osaka City University Graduate School of Medicine, Osaka, Japan

Androgen Excess as a Cause for Adipogenic Dysfunction in PCOS Women

First Posted Date
2013-06-28
Last Posted Date
2024-05-10
Lead Sponsor
University of California, Los Angeles
Target Recruit Count
45
Registration Number
NCT01889199
Locations
🇺🇸

UCaliforniaLA, Los Angeles, California, United States

Finite Androgen Ablation With or Without Abiraterone Acetate and Prednisone in Treating Patients With Recurrent Prostate Cancer

First Posted Date
2013-02-07
Last Posted Date
2024-11-29
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
310
Registration Number
NCT01786265
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Effects of Androgen Blockade on Sensitivity of the GnRH Pulse Generator to Suppression by Estradiol and Progesterone

First Posted Date
2011-09-02
Last Posted Date
2018-06-04
Lead Sponsor
University of Virginia
Target Recruit Count
4
Registration Number
NCT01428193
Locations
🇺🇸

Center for Research in Reproduction, University of Virginia, Charlottesville, Virginia, United States

Leuprorelin Associated With Radiotherapy Versus Leuprorelin Alone in T3 - T4 or pT3 (on Biopsy) N0, M0 Prostate Cancer

First Posted Date
2010-05-13
Last Posted Date
2015-07-29
Lead Sponsor
Takeda
Target Recruit Count
273
Registration Number
NCT01122121
Locations
🇫🇷

Clinique Mutualiste, Saint-etienne, France

Treatment of Hot Flushes Caused by Leuprorelin 11.25 mg in Prostate Adenocarcinoma

First Posted Date
2009-11-11
Last Posted Date
2015-07-30
Lead Sponsor
Takeda
Target Recruit Count
311
Registration Number
NCT01011751
Locations
🇫🇷

Professor Jacques IRANI, Poitiers, France

Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer

First Posted Date
2009-07-10
Last Posted Date
2024-10-10
Lead Sponsor
Radiation Therapy Oncology Group
Target Recruit Count
1538
Registration Number
NCT00936390
Locations
🇺🇸

Northside Hospital, Atlanta, Georgia, United States

🇺🇸

Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States

🇺🇸

Riverside Methodist Hospital, Columbus, Ohio, United States

and more 514 locations

Effect of High Testosterone on Sleep-associated Slowing of Follicular Luteinizing Hormone (LH) Frequency in Polycystic Ovary Syndrome

Phase 1
Active, not recruiting
Conditions
Interventions
First Posted Date
2009-06-30
Last Posted Date
2023-11-02
Lead Sponsor
University of Virginia
Target Recruit Count
72
Registration Number
NCT00930228
Locations
🇺🇸

University of Virginia, Charlottesville, Virginia, United States

Intermittent Hormonal Therapy With Leuprorelin and Flutamide in the Treatment of Stage D2 or TxNxM1b,c

Phase 2
Completed
Conditions
Interventions
First Posted Date
2009-01-06
Last Posted Date
2015-07-29
Lead Sponsor
Takeda
Target Recruit Count
341
Registration Number
NCT00817739

Radiation Therapy and Hormone Therapy in Treating Patients With Prostate Cancer

First Posted Date
2008-10-09
Last Posted Date
2017-01-04
Lead Sponsor
Radiation Therapy Oncology Group
Target Recruit Count
1322
Registration Number
NCT00769548
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