Gonadorelin
- Generic Name
- Gonadorelin
- Brand Names
- Lutrepulse
- Drug Type
- Small Molecule
- Chemical Formula
- C55H75N17O13
- CAS Number
- 33515-09-2
- Unique Ingredient Identifier
- 9O7312W37G
- Background
Gonadorelin is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pituitary.
- Indication
For evaluating the functional capacity and response of the gonadotropes of the anterior pituitary also for evaluating residual gonadotropic function of the pituitary following removal of a pituitary tumor by surgery and/or irradiation.
- Associated Therapies
- Ovulation induction therapy
Progesterone Primed Ovarian Stimulation Versus GnRH Antagonist Protocols in Women with Polycystic Ovarian Syndrome
- Conditions
- Controlled Ovarian HyperstimulationPolycystic Ovarian Syndrome
- Interventions
- First Posted Date
- 2025-02-06
- Last Posted Date
- 2025-02-25
- Lead Sponsor
- El Shatby University Hospital for Obstetrics and Gynecology
- Target Recruit Count
- 100
- Registration Number
- NCT06812559
- Locations
- 🇪🇬
ELShatby University Hospital, Alexandria, Egypt
Comparison of Progestin Primed Ovarian Stimulation (PPOS) vs.GnRH Antagonist Methods on IVF Outcomes
- Conditions
- IVFFertility IssuesInfertility
- Interventions
- First Posted Date
- 2024-05-02
- Last Posted Date
- 2024-07-17
- Lead Sponsor
- Nesta Clinic
- Target Recruit Count
- 152
- Registration Number
- NCT06396390
- Locations
- 🇹🇷
Nesta Clinic, Istanbul, Sisli, Turkey
GnRHa + Letrozole in Obese Progestin-insensitive Endometrial Atypical Hyperplasia Patients
- Conditions
- ObesityProgesterone ResistanceAtypical Endometrial Hyperplasia
- Interventions
- First Posted Date
- 2024-04-30
- Last Posted Date
- 2024-08-01
- Lead Sponsor
- Xiaojun Chen
- Target Recruit Count
- 29
- Registration Number
- NCT06390904
- Locations
- 🇨🇳
Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China
🇨🇳Tenth People's Hospital of Tongji University, Shanghai, Shanghai, China
NEPC Study: An Exploratory Safety and Efficacy Study With PSMA, SSTR2 and GRPR Targeted Radioligand Therapy in Metastatic Neuroendocrine Prostate Cancer.
- Conditions
- Metastatic Neuroendocrine Prostate Cancer
- Interventions
- Drug: [68Ga]Ga-PSMA-11Drug: Gonadotropin-releasing hormone (GnRH) analoguesDrug: Antiemetics & antinauseants
- First Posted Date
- 2024-04-23
- Last Posted Date
- 2025-04-04
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 36
- Registration Number
- NCT06379217
- Locations
- 🇺🇸
Seattle Cancer Care Alliance, Seattle, Washington, United States
🇺🇸Nebraska Cancer Specialists, Omaha, Nebraska, United States
🇺🇸Memorial Sloan Kettering Cancer Ctr, New York, New York, United States
GnRHa + Letrozole in Obese Progestin-insensitive Endometrial Cancer Patients
- Conditions
- Atypical Endometrial HyperplasiaProgesterone ResistanceObesityEndometrial Neoplasms
- Interventions
- First Posted Date
- 2024-04-23
- Last Posted Date
- 2024-08-01
- Lead Sponsor
- Xiaojun Chen
- Target Recruit Count
- 29
- Registration Number
- NCT06379113
- Locations
- 🇨🇳
Tenth People's Hospital of Tongji University, Shanghai, Shanghai, China
🇨🇳Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China
Dydrogesterone Versus GnRH Antagonist in Poor Responders Undergoing Double Ovarian Stimulation
- Conditions
- Infertility
- Interventions
- Drug: Progestin primed ovarian stimulation
- First Posted Date
- 2024-01-18
- Last Posted Date
- 2024-01-23
- Lead Sponsor
- Bedaya Hospital
- Target Recruit Count
- 120
- Registration Number
- NCT06212102
- Locations
- 🇪🇬
Bedaya Hospital, Giza, Egypt
Recall by Genotype: Neuropeptide Stimulation
- First Posted Date
- 2023-06-13
- Last Posted Date
- 2024-06-03
- Lead Sponsor
- Stephanie B. Seminara, MD
- Target Recruit Count
- 16
- Registration Number
- NCT05901467
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
Two Different Types of Luteal Phase Support in Natural Cycle Frozen Embryo Transfer and Its Effect on Pregnancy Rates
- Conditions
- Luteal Phase Support
- Interventions
- First Posted Date
- 2023-05-01
- Last Posted Date
- 2023-05-01
- Lead Sponsor
- Shaare Zedek Medical Center
- Target Recruit Count
- 144
- Registration Number
- NCT05838105
- Locations
- 🇮🇱
Shaare Zedek medical center, Jerusalem, Israel
Exploring the Relationship Between Androgen Metabolism, Metabolic Disease and Skeletal Muscle Energy Balance in Men
- Conditions
- Testosterone DeficiencyMetabolic DisturbanceCardiovascular DiseasesDiabetesHypogonadism, MaleAndrogen DeficiencyMetabolic DiseaseObesityNAFLDProstate Cancer
- Interventions
- First Posted Date
- 2023-03-17
- Last Posted Date
- 2023-03-17
- Lead Sponsor
- Royal College of Surgeons, Ireland
- Target Recruit Count
- 60
- Registration Number
- NCT05773183
- Locations
- 🇮🇪
Beaumont Hospital, Dublin 9, Ireland
Effect of GH Supplementation on the Blastocyst Euploid Rate in AMA Patients--A Retrospective Cohort Study
- Conditions
- Advanced Maternal AgePGT-AGrowth Hormone
- Interventions
- First Posted Date
- 2022-10-12
- Last Posted Date
- 2023-02-21
- Lead Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
- Target Recruit Count
- 692
- Registration Number
- NCT05574894
- Locations
- 🇨🇳
Shanghai JIAI Genetics and IVF Institute, Shanghai, Shanghai, China
Drug Development Updates
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