Gonadorelin
- Generic Name
- Gonadorelin
- Brand Names
- Lutrepulse
- Drug Type
- Small Molecule
- Chemical Formula
- C55H75N17O13
- CAS Number
- 33515-09-2
- Unique Ingredient Identifier
- 9O7312W37G
- Background
Gonadorelin is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pituitary.
- Indication
For evaluating the functional capacity and response of the gonadotropes of the anterior pituitary also for evaluating residual gonadotropic function of the pituitary following removal of a pituitary tumor by surgery and/or irradiation.
- Associated Therapies
- Ovulation induction therapy
GnRH Therapy on Cognition in Down Syndrome
- Conditions
- Olfaction DisordersDown SyndromeCognitive DeclineAlzheimer Disease, Early Onset
- Interventions
- Drug: 0.9% NaCl
- First Posted Date
- 2020-05-15
- Last Posted Date
- 2024-02-12
- Lead Sponsor
- Nelly Pitteloud
- Target Recruit Count
- 56
- Registration Number
- NCT04390646
- Locations
- 🇨🇭
Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Vaud, Switzerland
Benefit of GnRH Agonist Before Frozen Embryo Transfer in Patients With Endometriosis and/or Adenomyosis
- Conditions
- EndometriosisAdenomyosisInfertility, Female
- Interventions
- First Posted Date
- 2020-04-22
- Last Posted Date
- 2024-06-07
- Lead Sponsor
- Hopital Foch
- Target Recruit Count
- 180
- Registration Number
- NCT04356664
- Locations
- 🇫🇷
Hopital Foch, Suresnes, France
Mechanisms of Hypertension in Women With Polycystic Ovary Syndrome
- Conditions
- Polycystic Ovary SyndromeHypertension
- Interventions
- First Posted Date
- 2020-03-31
- Last Posted Date
- 2024-02-02
- Lead Sponsor
- Yale University
- Target Recruit Count
- 28
- Registration Number
- NCT04327934
- Locations
- 🇺🇸
The John B Pierce Laboratory, New Haven, Connecticut, United States
A Study of Apalutamide Combined With GnRH Agonist in Participants With Androgen Receptor Positive Salivary Gland Carcinoma
- Conditions
- Salivary Gland Neoplasms
- Interventions
- First Posted Date
- 2020-03-30
- Last Posted Date
- 2025-04-10
- Lead Sponsor
- Janssen Pharmaceutical K.K.
- Target Recruit Count
- 31
- Registration Number
- NCT04325828
- Locations
- 🇯🇵
National Cancer Center Hospital, Chuo Ku, Japan
🇯🇵National Hospital Organization Kyushu Medical Center, Fukuoka, Japan
🇯🇵Kansai Medical University Hospital, Hirakata City, Japan
Extended Letrozole Regimen Co-treatment With Gonadotropin Releasing Hormone Antagonist Protocol Versus Gonadotropin Releasing Hormone Antagonist Protocol in Poor Responders Undergoing IVF-ET
- First Posted Date
- 2020-02-13
- Last Posted Date
- 2020-02-13
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 106
- Registration Number
- NCT04268927
- Locations
- 🇪🇬
Obstetrics &Gynecology Department , Faculty of medicine ,Cairo university, Cairo, Egypt
🇪🇬Riyadh Fertility and Reproductive Health center, Giza, Egypt
Study of Abiraterone Acetate or Enzalutamide, Atezolizumab, GnRH Analog and Radiation Therapy in Men With Newly Diagnosed Hormone-sensitive Prostate Cancer
- Conditions
- Metastatic Prostate Cancer
- Interventions
- Radiation: Stereotactic Body Radiotherapy (SBRT)Other: Follow up
- First Posted Date
- 2020-02-10
- Last Posted Date
- 2025-04-27
- Lead Sponsor
- Memorial Sloan Kettering Cancer Center
- Target Recruit Count
- 28
- Registration Number
- NCT04262154
- Locations
- 🇺🇸
Memorial Sloan Kettering Nassau (Limited Protocol Activities), Uniondale, New York, United States
🇺🇸Memorial Sloan Kettering Cancer Commack (Limited Protocol Activities), Commack, New York, United States
🇺🇸Memorial Sloan Kettering Westchester (Limited Protocol Activities), Harrison, New York, United States
Cardiovascular Events in GnRH Agonist vs. Antagonist
- Conditions
- Hormone Sensitive Prostate CancerProstate CancerCardiac Event
- Interventions
- First Posted Date
- 2019-12-02
- Last Posted Date
- 2019-12-02
- Lead Sponsor
- Rabin Medical Center
- Target Recruit Count
- 80
- Registration Number
- NCT04182594
- Locations
- 🇮🇱
Rabin Medical Center - Beilinson Hospital, Petah Tikva, Israel
Micronized Progesterone vs Gonadotropin-releasing Hormone (GnRH) Antagonist in Freeze-all IVF Cycles.
- Conditions
- InfertilityIVFPreimplantation Diagnosis
- Interventions
- First Posted Date
- 2019-09-27
- Last Posted Date
- 2023-05-15
- Lead Sponsor
- Institut Universitari Dexeus
- Target Recruit Count
- 44
- Registration Number
- NCT04108039
- Locations
- 🇪🇸
Institut Universitari Dexeus, Barcelona, Catalunya, Spain
Comparative Study on the Efficacy of Ovarian Stimulation Protocols on the Success Rate of ICSI in Female Infertility
- Conditions
- Female InfertilityFemale Infertility Due to Ovulatory DisorderFemale Infertility of Tubal OriginPremature Ovarian FailurePolycystic Ovary SyndromeEctopic PregnancySalpingitisFemale Infertility Due to Tubal BlockFemale Infertility Due to Tubal OcclusionHydrosalpinx
- Interventions
- Drug: Human Chorionic Gonadotropin (hCG)Drug: Gonadotropins
- First Posted Date
- 2019-08-28
- Last Posted Date
- 2023-05-09
- Lead Sponsor
- Lebanese University
- Target Recruit Count
- 200
- Registration Number
- NCT04071574
- Locations
- 🇱🇧
Lebanese University, faculty of sciences III, Tripoli, North Lebanon, Lebanon
Bioenergetic Effects of Aging and Menopause (BEAM)
- Conditions
- AgingWeight GainObesity, AbdominalMenopause
- Interventions
- First Posted Date
- 2019-08-02
- Last Posted Date
- 2023-12-18
- Lead Sponsor
- University of Colorado, Denver
- Target Recruit Count
- 57
- Registration Number
- NCT04043520
- Locations
- 🇺🇸
University of Colorado - Anschutz Medical Campus, Aurora, Colorado, United States
Drug Development Updates
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