MedPath

Gonadorelin

Generic Name
Gonadorelin
Brand Names
Lutrepulse
Drug Type
Small Molecule
Chemical Formula
C55H75N17O13
CAS Number
33515-09-2
Unique Ingredient Identifier
9O7312W37G
Background

Gonadorelin is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pituitary.

Indication

For evaluating the functional capacity and response of the gonadotropes of the anterior pituitary also for evaluating residual gonadotropic function of the pituitary following removal of a pituitary tumor by surgery and/or irradiation.

Associated Therapies
Ovulation induction therapy

Luteal Phase Ovarian Stimulation With Follitropin Delta and Dydrogesterone

Not Applicable
Recruiting
Conditions
Oocyte Donation
Oocyte Donors
Interventions
First Posted Date
2022-08-30
Last Posted Date
2024-02-08
Lead Sponsor
CRG UZ Brussel
Target Recruit Count
50
Registration Number
NCT05521828
Locations
🇧🇪

Brussels Ivf, Brüssel, Belgium

GnRH Agonist for Luteal Phase Support.

Not Applicable
Conditions
Use of GnRH Agonist Alone for Luteal Phase Support in Fresh IVF Cycles
Interventions
First Posted Date
2022-08-02
Last Posted Date
2022-08-02
Lead Sponsor
Shaare Zedek Medical Center
Target Recruit Count
150
Registration Number
NCT05484193
Locations
🇮🇱

Shaare Zedek medical Center, Jerusalem, Israel

Effect of GH on the Blastocyst Euploid Rate in AMA Patients

Phase 3
Recruiting
Conditions
Age, Parental
Preimplantation Genetic Testing
Growth Hormone
Interventions
First Posted Date
2022-07-07
Last Posted Date
2025-02-12
Lead Sponsor
ShangHai Ji Ai Genetics & IVF Institute
Target Recruit Count
400
Registration Number
NCT05447208
Locations
🇨🇳

Shanghai JIAI Genetics and IVF Institute, Shanghai, Shanghai, China

Effects of Co-treatment on Endometrial abv3-integrin Expressions in Women With Recurrent Implantation Failure

Not Applicable
Completed
Conditions
Miscarriage, Recurrent
Interventions
First Posted Date
2022-06-29
Last Posted Date
2022-06-29
Lead Sponsor
Universiti Kebangsaan Malaysia Medical Centre
Target Recruit Count
39
Registration Number
NCT05437471
Locations
🇲🇾

UniversitiKMMC, Kuala Lumpur, Malaysia

Comparison of the Euploid Rate of Blastocyst Between PPOS and GnRH Antagonist Protocol in Women With PCOS Undergoing PGT-A

Phase 3
Not yet recruiting
Conditions
Preimplantation Genetic Testing
Progestin-primed Ovarian Stimulation
Polycystic Ovarian Syndrome
GnRH Antagonist
Interventions
First Posted Date
2022-04-13
Last Posted Date
2024-03-12
Lead Sponsor
ShangHai Ji Ai Genetics & IVF Institute
Target Recruit Count
204
Registration Number
NCT05326087

Efficacy of Prolonged GnRH Test in Male Adolescents With Postoperative HH

Not Applicable
Conditions
Hypogonadotropic Hypogonadism
Interventions
First Posted Date
2022-01-11
Last Posted Date
2022-01-11
Lead Sponsor
Huashan Hospital
Target Recruit Count
20
Registration Number
NCT05184374
Locations
🇨🇳

Huashan Hospital, Shanghai, Shanghai, China

Ovarian Hormone Regulation of Central and Cerebrovascular Hemodynamics (NoMEN Study)

Phase 4
Active, not recruiting
Conditions
Menopause
Estrogen Deficiency
Women
Aging
Interventions
First Posted Date
2021-09-27
Last Posted Date
2025-03-27
Lead Sponsor
University of Colorado, Denver
Target Recruit Count
55
Registration Number
NCT05057546
Locations
🇺🇸

University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado, United States

Prolonged Pulsatile Kisspeptin Administration in Hypogonadotropic Hypogonadism

Phase 2
Recruiting
Conditions
Hypogonadotropic Hypogonadism
Interventions
First Posted Date
2020-12-02
Last Posted Date
2025-03-04
Lead Sponsor
Stephanie B. Seminara, MD
Target Recruit Count
24
Registration Number
NCT04648969
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Live Birth Rate Between PPOS and GnRH Antagonist Protocol in Patients With Anticipated High Ovarian Response

Phase 3
Completed
Conditions
IVF
GnRH Antagonist
PPOS
Interventions
First Posted Date
2020-06-04
Last Posted Date
2023-08-30
Lead Sponsor
ShangHai Ji Ai Genetics & IVF Institute
Target Recruit Count
784
Registration Number
NCT04414761
Locations
🇨🇳

ShangHai JIAI Genetics&IVF Institute, Shanghai, China

Comparison of the Euploid Rate of Blastocyst Between PPOS and GnRH Antagonist Protocol in Patients Undergoing PGT-A

Phase 3
Recruiting
Conditions
Progestin-primed Ovarian Stimulation
GnRH Antagonist
Preimplantation Genetic Testing
Euploid Rate
Interventions
First Posted Date
2020-06-04
Last Posted Date
2024-03-12
Lead Sponsor
ShangHai Ji Ai Genetics & IVF Institute
Target Recruit Count
400
Registration Number
NCT04414748
Locations
🇨🇳

Shanghai JiAi Genetics & IVF Institute, Shanghai, Shanghai, China

© Copyright 2025. All Rights Reserved by MedPath