Gonadorelin
- Generic Name
- Gonadorelin
- Brand Names
- Lutrepulse
- Drug Type
- Small Molecule
- Chemical Formula
- C55H75N17O13
- CAS Number
- 33515-09-2
- Unique Ingredient Identifier
- 9O7312W37G
- Background
Gonadorelin is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pituitary.
- Indication
For evaluating the functional capacity and response of the gonadotropes of the anterior pituitary also for evaluating residual gonadotropic function of the pituitary following removal of a pituitary tumor by surgery and/or irradiation.
- Associated Conditions
- -
- Associated Therapies
- Ovulation induction therapy
Recall by Genotype: Neuropeptide Stimulation
- First Posted Date
- 2023-06-13
- Last Posted Date
- 2024-06-03
- Lead Sponsor
- Stephanie B. Seminara, MD
- Target Recruit Count
- 16
- Registration Number
- NCT05901467
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
Exploring the Relationship Between Androgen Metabolism, Metabolic Disease and Skeletal Muscle Energy Balance in Men
- First Posted Date
- 2023-03-17
- Last Posted Date
- 2023-03-17
- Lead Sponsor
- Royal College of Surgeons, Ireland
- Target Recruit Count
- 60
- Registration Number
- NCT05773183
- Locations
- 🇮🇪
Beaumont Hospital, Dublin 9, Ireland
Efficacy of Prolonged GnRH Test in Male Adolescents With Postoperative HH
- First Posted Date
- 2022-01-11
- Last Posted Date
- 2022-01-11
- Lead Sponsor
- Huashan Hospital
- Target Recruit Count
- 20
- Registration Number
- NCT05184374
- Locations
- 🇨🇳
Huashan Hospital, Shanghai, Shanghai, China
Prolonged Pulsatile Kisspeptin Administration in Hypogonadotropic Hypogonadism
- Conditions
- Interventions
- First Posted Date
- 2020-12-02
- Last Posted Date
- 2024-08-01
- Lead Sponsor
- Stephanie B. Seminara, MD
- Target Recruit Count
- 24
- Registration Number
- NCT04648969
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
Pulsatile Gonadotropin-releasing Hormone for Infertility in Non-obese Patients With Polycystic Ovary Syndrome
- Conditions
- Interventions
- First Posted Date
- 2019-06-18
- Last Posted Date
- 2019-06-18
- Lead Sponsor
- RenJi Hospital
- Target Recruit Count
- 78
- Registration Number
- NCT03989024
- Locations
- 🇨🇳
Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China
Hormonal Mechanisms of Sleep Restriction - Axis Study
- Conditions
- Interventions
- Drug: GonadorelinDrug: GanirelixDrug: Ketoconazole PillDrug: Dexamethasone InjectionDrug: CorticorelinDrug: Hydrocortisone InjectionDrug: DexamethasoneDrug: Placebo oral capsuleDrug: Cosyntropin Injectable ProductDrug: Saline SolutionDrug: Recombinant Human Luteinizing HormoneDrug: Saline Solution for Injection
- First Posted Date
- 2017-05-08
- Last Posted Date
- 2024-04-23
- Target Recruit Count
- 80
- Registration Number
- NCT03142893
- Locations
- 🇺🇸
Los Angeles Biomedical Research Institute, Torrance, California, United States
Randomized Phase II Study of Salvage XRT + ADT +/- Abiraterone and Apalutamide for Rising PSA After RP (FORMULA-509)
- Conditions
- Interventions
- First Posted Date
- 2017-05-05
- Last Posted Date
- 2024-05-14
- Lead Sponsor
- Dana-Farber Cancer Institute
- Target Recruit Count
- 345
- Registration Number
- NCT03141671
- Locations
- 🇺🇸
University of Chicago, Chicago, Illinois, United States
🇺🇸MD Anderson Cancer Center, Houston, Texas, United States
🇺🇸Yale Cancer Center, New Haven, Connecticut, United States
Administration of Kisspeptin in Patients With Hyperprolactinemia
- Conditions
- Interventions
- First Posted Date
- 2016-11-06
- Last Posted Date
- 2024-10-01
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 36
- Registration Number
- NCT02956447
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
Efficacy of Pulsatile GnRH Therapy on Male Patients With Pituitary Stalk Interruption Syndrome
- Conditions
- Interventions
- First Posted Date
- 2016-03-10
- Last Posted Date
- 2016-03-10
- Lead Sponsor
- Peking Union Medical College Hospital
- Target Recruit Count
- 20
- Registration Number
- NCT02705014
- Locations
- 🇨🇳
Peking Union Medical College Hospital, Beijing, Beijing, China
Reprometabolic Syndrome Mediates Subfertility in Obesity
- Conditions
- Interventions
- First Posted Date
- 2016-01-12
- Last Posted Date
- 2024-11-29
- Lead Sponsor
- University of Colorado, Denver
- Target Recruit Count
- 84
- Registration Number
- NCT02653092
- Locations
- 🇺🇸
University of Colorado Denver, Aurora, Colorado, United States
Drug Development Updates
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