MedPath

Etomidate

Generic Name
Etomidate
Brand Names
Amidate
Drug Type
Small Molecule
Chemical Formula
C14H16N2O2
CAS Number
33125-97-2
Unique Ingredient Identifier
Z22628B598
Background

Imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic.

Indication

Used in the induction of general anesthesia.

Associated Therapies
General Anesthesia

Bispectral Index Guiding Etomidate Used in Children Aged 3 to 10 for Clinical Anesthesia Induction

Phase 4
Conditions
Bispectral Index
Pediatric
Etomidate
Induction
Interventions
First Posted Date
2014-07-08
Last Posted Date
2014-07-08
Lead Sponsor
Henan Provincial People's Hospital
Target Recruit Count
120
Registration Number
NCT02182648

The Application of Target Controlled Infusion of Etomidate Combined With Propofol in the Maintenance of Anesthesia During Brain Surgeries

Phase 4
Conditions
Target Controlled Infusion
General Anesthesia
Interventions
First Posted Date
2014-06-25
Last Posted Date
2014-06-25
Lead Sponsor
Henan Provincial People's Hospital
Target Recruit Count
120
Registration Number
NCT02174120

A Comparison Between Propofol and Etomidate in Hysteroscopy on Effect of Postoperative Sedation and Cognitive Function in Elderly Patients

Phase 4
Conditions
Hysteroscopy
Hemodynamics
Sedation
Interventions
First Posted Date
2014-05-28
Last Posted Date
2014-05-28
Lead Sponsor
Shaanxi Provincial People's Hospital
Target Recruit Count
120
Registration Number
NCT02147678

Effect of Pre-injection of Lidocaine on Myoclonus Induced by Induction With Etomidate in Elderly Patients During General Anesthesia

First Posted Date
2014-05-19
Last Posted Date
2014-05-19
Lead Sponsor
Tang-Du Hospital
Target Recruit Count
272
Registration Number
NCT02141737
Locations
🇨🇳

TangDu Hospital,FMMU, Xi'an, Shanxi, China

Ketamine / Propofol Admixture "Ketofol" at Induction in the Critically Ill Against Etomidate: KEEP PACE Trial

Phase 2
Completed
Conditions
Critical Illness
Interventions
First Posted Date
2014-04-07
Last Posted Date
2020-06-16
Lead Sponsor
Mayo Clinic
Target Recruit Count
160
Registration Number
NCT02105415
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

The Efficacy And Cognitive Impairment Of Modified Electroconvulsive Therapy

Not Applicable
Completed
Conditions
Major Depressive Disorder
Interventions
Device: The right temporal MECT
Device: Bilateral temporal MECT
Device: Bilateral frontal MECT
First Posted Date
2014-02-19
Last Posted Date
2018-04-23
Lead Sponsor
Shanghai Mental Health Center
Target Recruit Count
280
Registration Number
NCT02066077
Locations
🇨🇳

Shanghai Mental Health Center, Shanghai, China

Etomidate vs. Midazolam for Sedation During ERCP

Phase 4
Completed
Conditions
Choledocholithiasis
Cholangiocarcinoma
Pancreatitis
Pancreatic Cancer
Interventions
First Posted Date
2014-01-06
Last Posted Date
2015-06-29
Lead Sponsor
Cheju Halla General Hospital
Target Recruit Count
63
Registration Number
NCT02027311
Locations
🇰🇷

1Digestive Disease Center and Department of Internal Medicine, Cheju Halla General Hospital, Jeju-si, Jeju Special Self-Governing Province, Korea, Republic of

Effects of Etomidate on Postoperative Circadian Rhythm Changes of Salivary Cortisol in Children

Phase 4
Conditions
Congenital Hydronephrosis
Congenital Choledochal Cyst
Fracture
Interventions
First Posted Date
2013-12-17
Last Posted Date
2013-12-17
Lead Sponsor
Du yi
Target Recruit Count
30
Registration Number
NCT02013986
Locations
🇨🇳

department of anesthesia of Xinhua Hospital, Shanghai, Shanghai, China

Combined Use of Etomidate and Propofol in Painless Gastroscopy.

First Posted Date
2013-07-31
Last Posted Date
2013-12-16
Lead Sponsor
Jiangsu Nhwa Pharmaceutical Co., Ltd.
Target Recruit Count
2450
Registration Number
NCT01913054
Locations
🇨🇳

The Affiliated Hospital of Xuzhou Medical College, Xuzhou, Jiangsu, China

🇨🇳

General Hospital of Chinese Air Force, Peking, Beijing, China

🇨🇳

Chaoyang Hospital Attached to the Capital Medical University, Peking, Beijing, China

and more 3 locations

Ketamine Versus Etomidate for Rapid Sequence Intubation

Phase 4
Completed
Conditions
Airway Control
Anesthesia
Intubation
Complication
Interventions
First Posted Date
2013-04-04
Last Posted Date
2019-05-24
Lead Sponsor
Hennepin Healthcare Research Institute
Target Recruit Count
143
Registration Number
NCT01823328
Locations
🇺🇸

Hennepin County Medical Center, Minneapolis, Minnesota, United States

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