Granisetron

Generic Name
Granisetron
Brand Names
Sancuso, Sustol
Drug Type
Small Molecule
Chemical Formula
C18H24N4O
CAS Number
109889-09-0
Unique Ingredient Identifier
WZG3J2MCOL
Background

A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients.

Indication

For the prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer therapy (including high dose cisplatin), postoperation, and radiation (including total body irradiation and daily fractionated abdominal radiation).

Associated Conditions
Nausea and vomiting
Associated Therapies
-

A Study of Ramosetron Plus DX, Dexamethasone, Compared to Granisetron Plus DX for the Prevention of Vomiting and Nausea

Phase 3
Completed
Conditions
Interventions
First Posted Date
2006-01-05
Last Posted Date
2017-03-09
Lead Sponsor
Astellas Pharma Inc
Target Recruit Count
287
Registration Number
NCT00272285

A Study of Kytril (Granisetron) in the Prevention of Post-Operative Nausea and Vomiting (PONV) in Pediatric Subjects Undergoing Tonsillectomy or Adenotonsillectomy

Phase 4
Completed
Conditions
Interventions
First Posted Date
2005-10-04
Last Posted Date
2018-03-27
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
171
Registration Number
NCT00231478
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