Norepinephrine

Generic Name
Norepinephrine
Brand Names
Levophed
Drug Type
Small Molecule
Chemical Formula
C8H11NO3
CAS Number
51-41-2
Unique Ingredient Identifier
X4W3ENH1CV
Background

Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.

Indication

Mainly used to treat patients in vasodilatory shock states such as septic shock and neurogenic shock and has shown a survival benefit over dopamine. Also used as a vasopressor medication for patients with critical hypotension.

Associated Conditions
Cardiac Arrest, Severe hypotension, Shock, Acute, severe Hypotension
Associated Therapies
-
Clinical Trials
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