Lithium carbonate
- Generic Name
- Lithium carbonate
- Brand Names
- Carbolith, Lithane, Lithmax, Lithobid
- Drug Type
- Small Molecule
- Chemical Formula
- CLi2O3
- CAS Number
- 554-13-2
- Unique Ingredient Identifier
- 2BMD2GNA4V
- Background
Lithium has been used to treat manic episodes since the 19th century. Though it is widely used, its mechanism of action is still unknown. Lithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse effects.
- Indication
Lithium carbonate is indicated as a monotherapy for the treatment of acute manic and mixed episodes associated with bipolar 1 disorder in patients ≥7 years of age. It is also indicated as a maintenance treatment for bipolar 1 disorder in patients ≥7 years of age.
- Associated Conditions
- Bipolar 1 Disorder, Mixed manic depressive episode, Acute Manic episode
- Associated Therapies
- -
Efficacy and Safety of Lithium Carbonate in the Treatment of Chronic Spinal Cord Injuries
- First Posted Date
- 2008-09-10
- Last Posted Date
- 2015-05-04
- Lead Sponsor
- China Spinal Cord Injury Network
- Target Recruit Count
- 40
- Registration Number
- NCT00750061
- Locations
- 🇨🇳
Buddhist Tzu Chi General Hospital, Taichung Branch, Taichung, Taiwan
🇨🇳China Rehabilitation and Research Center, Beijing, China
Lithium Treatment for Patients With Spinocerebellar Ataxia Type I
- Conditions
- First Posted Date
- 2008-05-26
- Last Posted Date
- 2019-12-17
- Target Recruit Count
- 13
- Registration Number
- NCT00683943
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
Effectiveness of Lithium Plus Optimized Medication in Treating People With Bipolar Disorder
- Conditions
- Interventions
- First Posted Date
- 2008-04-28
- Last Posted Date
- 2018-02-13
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 283
- Registration Number
- NCT00667745
- Locations
- 🇺🇸
Case Western Reserve University, Cleveland, Ohio, United States
🇺🇸University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States
🇺🇸Stanford University, Stanford, California, United States
Antidepressant Therapy for Bipolar II Major Depression
- Conditions
- Interventions
- First Posted Date
- 2008-03-24
- Last Posted Date
- 2008-03-24
- Lead Sponsor
- Stanley Medical Research Institute
- Target Recruit Count
- 90
- Registration Number
- NCT00641927
- Locations
- 🇺🇸
Depression Research Unit, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States
Antidepressant Therapy in Treating Bipolar Type II Major Depression
- Conditions
- Interventions
- First Posted Date
- 2008-01-28
- Last Posted Date
- 2017-04-25
- Lead Sponsor
- University of Pennsylvania
- Target Recruit Count
- 140
- Registration Number
- NCT00602537
- Locations
- 🇺🇸
Depression Research Unit - University of Pennsylvania, Philadelphia, Pennsylvania, United States
An Initial Study of Lithium in Patients With Medullary Thyroid Cancer
- First Posted Date
- 2007-12-28
- Last Posted Date
- 2019-12-09
- Lead Sponsor
- University of Wisconsin, Madison
- Target Recruit Count
- 5
- Registration Number
- NCT00582712
- Locations
- 🇺🇸
Uniersity of Wisconsin Comprehensive Cancer Center, Madison, Wisconsin, United States
Lithium for Low-Grade Neuroendocrine Tumors
- First Posted Date
- 2007-07-16
- Last Posted Date
- 2019-11-26
- Lead Sponsor
- University of Wisconsin, Madison
- Target Recruit Count
- 15
- Registration Number
- NCT00501540
- Locations
- 🇺🇸
University of Wisconsin Paul P. Carbone Comprehensive Cancer Center, Madison, Wisconsin, United States
Olanzapine Versus Comparator in the Treatment of Bipolar Disorder
- Conditions
- First Posted Date
- 2007-06-13
- Last Posted Date
- 2007-06-13
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 140
- Registration Number
- NCT00485680
- Locations
- 🇨🇳
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Shanghai, China
Ph I Study of Lithium During Whole Brain Radiotherapy For Patients With Brain Metastases
- First Posted Date
- 2007-05-07
- Last Posted Date
- 2012-02-28
- Lead Sponsor
- Vanderbilt-Ingram Cancer Center
- Target Recruit Count
- 9
- Registration Number
- NCT00469937
- Locations
- 🇺🇸
Vanderbilt-Ingram Cancer Center - Cool Springs, Nashville, Tennessee, United States
🇺🇸Vanderbilt-Ingram Cancer Center at Franklin, Nashville, Tennessee, United States
🇺🇸Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, United States
Lithium for the Treatment of Pediatric Mania
- Conditions
- Interventions
- First Posted Date
- 2007-03-01
- Last Posted Date
- 2012-02-28
- Target Recruit Count
- 61
- Registration Number
- NCT00442039
- Locations
- 🇺🇸
CASE Western Reserve University, Cleveland, Ohio, United States
Drug Development Updates
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