MedPath

Sulfadoxine

Generic Name
Sulfadoxine
Drug Type
Small Molecule
Chemical Formula
C12H14N4O4S
CAS Number
2447-57-6
Unique Ingredient Identifier
88463U4SM5
Background

A long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract, and malarial infections.

Indication

Sulfadoxine is used in combination with pyrimethamine for the treatment or prevention of malaria. It can also be used to treat various infections in livestock as well.

Sulfadoxine and pyrimethamine is indicated for the treatment of Plasmodium falciparum malaria in those patients in whom chloroquine resistance is suspected.

Associated Conditions
Malaria, Malaria caused by Plasmodium falciparum, Acute, uncomplicated Malaria caused by plasmodium falciparum

Sulfadoxine- Pyrimethamine Versus Weekly Chloroquine for Malaria Prevention in Children With Sickle Cell Anemia

Phase 3
Completed
Conditions
Sickle Cell Anemia
Malaria
Interventions
First Posted Date
2006-11-14
Last Posted Date
2009-07-02
Lead Sponsor
Makerere University
Target Recruit Count
220
Registration Number
NCT00399074
Locations
🇺🇬

Mulago Hospital, Kampala, Central, Uganda

Comparison of Two Strategies for the Delivery of IPTc

Phase 4
Completed
Conditions
Malaria
First Posted Date
2006-09-14
Last Posted Date
2017-02-10
Lead Sponsor
London School of Hygiene and Tropical Medicine
Target Recruit Count
14000
Registration Number
NCT00376155
Locations
🇬🇲

MRC Laboratories, Banjul, Gambia

Intermittent Treatment With Sulfadoxine-pyrimethamine for Malaria Control in Infants

Phase 4
Completed
Conditions
Malaria
Anemia
First Posted Date
2005-09-21
Last Posted Date
2010-03-30
Lead Sponsor
Bernhard Nocht Institute for Tropical Medicine
Target Recruit Count
1070
Registration Number
NCT00206739
Locations
🇬🇭

Kumasi Centre for Collaborative Research in Tropical Medicine, Kumasi, Ashanti Region, Ghana

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