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Zoliflodacin

Generic Name
Zoliflodacin
Drug Type
Small Molecule
Chemical Formula
C22H22FN5O7
CAS Number
1620458-09-4
Unique Ingredient Identifier
FWL2263R77
Background

Zoliflodacin has been used in trials studying the basic science and treatment of Gonorrhoea.

Clinical Trials
Related News

Zoliflodacin Bioequivalence and Drug-Drug Interaction Study

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
First Posted Date
2022-12-02
Last Posted Date
2023-03-01
Lead Sponsor
Global Antibiotics Research and Development Partnership
Target Recruit Count
50
Registration Number
NCT05635305
Locations
πŸ‡©πŸ‡ͺ

Parexel Early Phase Clinical Unit, Berlin, Germany

Zoliflodacin in Uncomplicated Gonorrhoea

Phase 3
Completed
Conditions
Gonorrhea
Interventions
First Posted Date
2019-05-22
Last Posted Date
2024-07-26
Lead Sponsor
Global Antibiotics Research and Development Partnership
Target Recruit Count
1011
Registration Number
NCT03959527
Locations
πŸ‡ΊπŸ‡Έ

Public Health - Seattle & King County STD Clinic, Seattle, Washington, United States

πŸ‡ΊπŸ‡Έ

Jefferson County Department of Health, Birmingham, Alabama, United States

πŸ‡ΊπŸ‡Έ

University of Alabama at Birmingham, Birmingham, Alabama, United States

and more 14 locations

Study to Investigate Effect of Food and Safety of a New Formulation of Zoliflodacin

Phase 1
Completed
Conditions
Gonorrhea
Interventions
Other: high calorie, high fat breakfast
First Posted Date
2018-10-24
Last Posted Date
2018-12-06
Lead Sponsor
Drugs for Neglected Diseases
Target Recruit Count
48
Registration Number
NCT03718806
Locations
πŸ‡ΊπŸ‡Έ

Quotient Sciences, Miami, Florida, United States

Thorough QT/QTC (TQT) Clinical Trial to Evaluate the Effect of Zoliflodacin on Cardiac Repolarization in Healthy Male and Female Subjects

Phase 1
Completed
Conditions
Gonococcal Infection
Electrocardiogram Repolarisation Abnormality
Interventions
Other: Placebo
First Posted Date
2018-08-03
Last Posted Date
2020-03-27
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
72
Registration Number
NCT03613649
Locations
πŸ‡ΊπŸ‡Έ

Vince and Associates Clinical Research, Overland Park, Kansas, United States

A Study to Evaluate the Safety, Tolerability and Plasma PK of a Single Oral Dose of Zoliflodacin in Healthy Male and Female Volunteers

Phase 1
Completed
Conditions
Gonorrhoea
Interventions
First Posted Date
2018-01-19
Last Posted Date
2019-03-18
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
8
Registration Number
NCT03404167
Locations
πŸ‡ΊπŸ‡Έ

Quintiles Phase I Services - Overland Park, Overland Park, Kansas, United States

AZD0914 Phase 1 ADME Study in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2014-11-24
Last Posted Date
2015-06-03
Lead Sponsor
Entasis Therapeutics
Target Recruit Count
6
Registration Number
NCT02298920
Locations
πŸ‡ΊπŸ‡Έ

Research Site, Madison, Wisconsin, United States

πŸ‡ΊπŸ‡Έ

Covance Clinical Research Unit, Madison, Wisconsin, United States

Randomized, Open-label Phase 2 Study of Oral AZD0914 in the Treatment of Gonorrhea

Phase 2
Completed
Conditions
Gonorrhoea
Interventions
First Posted Date
2014-10-07
Last Posted Date
2017-03-22
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
180
Registration Number
NCT02257918
Locations
πŸ‡ΊπŸ‡Έ

Indiana University - Bell Flower Clinic, Indianapolis, Indiana, United States

πŸ‡ΊπŸ‡Έ

Durham County Health Department, Durham, North Carolina, United States

πŸ‡ΊπŸ‡Έ

Public Health STD Clinic, Seattle, Washington, United States

and more 2 locations
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