Magnesium sulfate
- Generic Name
- Magnesium sulfate
- Brand Names
- Concept Ob, Suflave, Suprep Bowel Prep Kit, Tis-U-sol
- Drug Type
- Small Molecule
- Chemical Formula
- MgO4S
- CAS Number
- 7487-88-9
- Unique Ingredient Identifier
- ML30MJ2U7I
- Background
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual, 199...
- Indication
Used for immediate control of life-threatening convulsions in the treatment of severe toxemias (pre-eclampsia and eclampsia) of pregnancy and in the treatment of acute nephritis in children. Also indicated for replacement therapy in magnesium deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those of hypocalcemia. Also ...
- Associated Conditions
- Constipation, Convulsions, Hypomagnesemia, Torsades de Pointes, Barium poisoning, Severe Exacerbation of asthma
- Associated Therapies
- Bowel preparation therapy, Soaking aid for minor sprains and bruises
Effect of Magnesium Sulphate Pretreatment in Pediatric Abdominal Surgery
- Conditions
- Interventions
- First Posted Date
- 2023-02-21
- Last Posted Date
- 2024-06-25
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 58
- Registration Number
- NCT05736744
- Locations
- 🇪🇬
Pediatric hospital, faculty of medicine, Assiut university, Assiut, Assiut Governorate, Egypt
🇪🇬Pediatric hospital, Assiut, Assiut Governorate, Egypt
MAGIC AKI: Magnesium for the Prevention of HIOC-Associated AKI
- First Posted Date
- 2023-02-16
- Last Posted Date
- 2024-08-13
- Lead Sponsor
- Brigham and Women's Hospital
- Target Recruit Count
- 130
- Registration Number
- NCT05730816
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
Neuroprotective Efficacy of Postnatal Magnesium Sulphate in Term Infants With Birth Asphyxia
- First Posted Date
- 2023-02-01
- Last Posted Date
- 2023-02-14
- Lead Sponsor
- University of Health Sciences Lahore
- Target Recruit Count
- 178
- Registration Number
- NCT05707962
Dexmedetomidine Versus Magnesium Sulfate in Ultrasound Guided Bilateral Bi-level Erector Spinae Plane Block in Corrective Scoliosis Surgery
- Conditions
- Interventions
- First Posted Date
- 2023-01-04
- Last Posted Date
- 2024-07-30
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 60
- Registration Number
- NCT05671081
- Locations
- 🇪🇬
Ain Shams University hospitals, Cairo, Egypt
Peri-Operative Magnesium Infusion to Prevent Atrial Fibrillation Evaluated.
- First Posted Date
- 2022-12-30
- Last Posted Date
- 2024-08-28
- Lead Sponsor
- HagaZiekenhuis
- Target Recruit Count
- 265
- Registration Number
- NCT05669417
- Locations
- 🇳🇱
HagaZiekenhuis, The Hague, South-Holland, Netherlands
Block Pressor Response to Intubation
- Conditions
- Interventions
- First Posted Date
- 2022-12-21
- Last Posted Date
- 2022-12-21
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 102
- Registration Number
- NCT05659212
Effects Of Additional MgSO4 30 Mg/KgBW Intravenous and Ketorolac
- First Posted Date
- 2022-11-08
- Last Posted Date
- 2022-11-08
- Lead Sponsor
- Indonesia University
- Target Recruit Count
- 48
- Registration Number
- NCT05609955
- Locations
- 🇮🇩
Cipto Mangunkusumo Cental National Hospital, Jakarta, DKI Jakarta, Indonesia
Ketamine Versus Magnesium as Analgesic Adjuvants in Pediatric Adenotonsillectomy
- Conditions
- Interventions
- First Posted Date
- 2022-10-04
- Last Posted Date
- 2024-02-28
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 38
- Registration Number
- NCT05565664
- Locations
- 🇪🇬
Faculty of Medicine, Cairo University, Cairo, Egypt
Dexmedetomidine and Magnesium Sulfate in Preventing Junctional Ectopic Tachycardia After Pediatric Cardiac Surgery
- Conditions
- Interventions
- First Posted Date
- 2022-09-26
- Last Posted Date
- 2024-04-18
- Lead Sponsor
- Kasr El Aini Hospital
- Target Recruit Count
- 120
- Registration Number
- NCT05554848
- Locations
- 🇪🇬
Kasralainy Faculty of Medicine, Cairo, Egypt
The Treatment of Magnesium Sulfate and Nifedipine in Preterm Labor Threat
- Conditions
- Interventions
- First Posted Date
- 2022-08-29
- Last Posted Date
- 2022-09-15
- Lead Sponsor
- Konya Meram State Hospital
- Target Recruit Count
- 30
- Registration Number
- NCT05520021
- Locations
- 🇹🇷
Hasan Ali Inal, Antalya, Turkey
Drug Development Updates
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