Remimazolam

Generic Name: Remimazolam

Brand Names: Byfavo

Drug Type: Small Molecule

Chemical Formula: C_₂₁H_₁₉BrN_₄O_₂

CAS Number: 308242-62-8

Unique Ingredient Identifier: 7V4A8U16MB

Background: Remimazolam is an ultra short-acting benzodiazepine used in the induction and maintenance of sedation during short (<30 minute) procedures. Recent trends in anesthesia-related drug development have touted the benefits of so-called "soft drugs" - these agents, such as remifentanil, are designed to be metabolically fragile and thus susceptible to rapid biotran...

Indication: Remimazolam is indicated for the induction and maintenance of procedural sedation in adults undergoing procedures lasting 30 minutes or less.

Associated Conditions: Procedural Sedation

Associated Therapies: -

Clinical Trials

Remimazolam Besylate and Propofol Sedation on Hemodynamic for Coronary Artery Bypass Graft Patients

Not Applicable

Not yet recruiting

Conditions: Coronary Artery Disease

Interventions: Drug: Remimazolam
Drug: Propofol

First Posted Date: 2024-07-11

Last Posted Date: 2024-07-11

Lead Sponsor: Shanghai Zhongshan Hospital

Target Recruit Count: 338

Registration Number: NCT06496165

Locations: 🇨🇳
Zhongshan Hospital Fudan university, Shanghai, Shanghai, China

Paradoxical Reactions of Remimazolam in Pediatric Painless Gastrointestinal Endoscopy

Not Applicable

Completed

Conditions: Endoscopy, Gastrointestinal

Interventions: Drug: Remimazolam

First Posted Date: 2024-05-17

Last Posted Date: 2024-10-30

Lead Sponsor: Tongji Hospital

Target Recruit Count: 333

Registration Number: NCT06419543

Locations: 🇨🇳
Tongji hospital, Wuhan, Hubei, China

Effect of Combined Administration of Sevoflurane and Remimazolam on Emergence

Not Applicable

Recruiting

Conditions: Gynecological Surgery

Interventions: Drug: Remimazolam

First Posted Date: 2024-04-25

Last Posted Date: 2024-06-07

Lead Sponsor: Pusan National University Yangsan Hospital

Target Recruit Count: 24

Registration Number: NCT06385002

Locations: 🇰🇷
Pusan National University Yangsan Hospital, Yangsan, Korea, Republic of

ED90 of Remimazolam Anesthesia Induction in Drug-induced Sleep Endoscopy in Adults

Phase 4

Recruiting

Conditions: Effect of Drug

Interventions: Drug: Remimazolam

First Posted Date: 2024-03-27

Last Posted Date: 2024-05-02

Lead Sponsor: Tongji Hospital

Target Recruit Count: 165

Registration Number: NCT06333145

Locations: 🇨🇳
Tongji Hospital, Wuhan, Hubei, China

Esketamine vs Remimazolam for Postoperative Sleep Disturbance and Anxiety

Not Applicable

Recruiting

Conditions: Sleep Disturbance

Interventions: Drug: normal Saline
Drug: Esketamine
Drug: Remimazolam

First Posted Date: 2024-02-29

Last Posted Date: 2024-03-05

Lead Sponsor: Tianjin Medical University General Hospital

Target Recruit Count: 300

Registration Number: NCT06284668

Locations: 🇨🇳
Tianjin Medical University General Hospital, Tianjin, China

Remimazolam in High Risk ERCP Patients

Not Applicable

Not yet recruiting

Conditions: the Severity and Duration of Intraoperative Hypotension

Interventions: Drug: placebo
Drug: Remimazolam

First Posted Date: 2024-02-14

Last Posted Date: 2024-02-16

Lead Sponsor: National Taiwan University Hospital

Target Recruit Count: 60

Registration Number: NCT06258356

Ketamine for Veterans With Parkinson's Disease

Phase 2

Not yet recruiting

Conditions: Parkinson's Disease

Interventions: Drug: Ketamine
Drug: Remimazolam

First Posted Date: 2024-01-30

Last Posted Date: 2024-08-12

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 80

Registration Number: NCT06231563

Locations: 🇺🇸
San Francisco VA Medical Center, San Francisco, CA, San Francisco, California, United States

Comparison of Emergence Delirium: Remimazolam vs Sevoflurane Anesthesia

Phase 4

Not yet recruiting

Conditions: Emergence Delirium

Interventions: Drug: Remimazolam
Drug: Sevoflurane

First Posted Date: 2024-01-19

Last Posted Date: 2024-01-19

Lead Sponsor: Second Affiliated Hospital of Wenzhou Medical University

Target Recruit Count: 90

Registration Number: NCT06214117

Locations: 🇨🇳
The second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China

The Effects of Remimazolam on the Incidence of Severe Hypoxia During Sedated Hysteroscopy for Assisted Reproduction in Overweight or Obese Patients

Not Applicable

Recruiting

Conditions: Hysteroscopy
Overweight or Obesity
Hypoxia

Interventions: Drug: remimazolam
Drug: Propofol

First Posted Date: 2024-01-03

Last Posted Date: 2024-07-23

Lead Sponsor: RenJi Hospital

Target Recruit Count: 600

Registration Number: NCT06187896

Locations: 🇨🇳
Diansan Su, Shanghai, Shanghai, China

Effect of Remimazolam on Postoperative Delirium

Not Applicable

Recruiting

Conditions: General Anesthetic Drug Adverse Reaction

Interventions: Drug: remimazolam
Drug: propofol

First Posted Date: 2023-12-26

Last Posted Date: 2023-12-26

Lead Sponsor: Zhihong LU

Target Recruit Count: 190

Registration Number: NCT06180876

Locations: 🇨🇳
Xijing hospital, Fourth military medical university, Xi'an, Shaanxi, China

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